FI885783A0 - Icke-peptidiska inhibitorer av renin. - Google Patents
Icke-peptidiska inhibitorer av renin.Info
- Publication number
- FI885783A0 FI885783A0 FI885783A FI885783A FI885783A0 FI 885783 A0 FI885783 A0 FI 885783A0 FI 885783 A FI885783 A FI 885783A FI 885783 A FI885783 A FI 885783A FI 885783 A0 FI885783 A0 FI 885783A0
- Authority
- FI
- Finland
- Prior art keywords
- alkyl
- renin
- peptidiska
- inhibitorer
- icke
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
- C07D207/34—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/08—Indoles; Hydrogenated indoles with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, directly attached to carbon atoms of the hetero ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
- C07D209/42—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/48—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
- C07D215/54—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3
- C07D215/56—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3 with oxygen atoms in position 4
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
- C07D241/36—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings condensed with carbocyclic rings or ring systems
- C07D241/38—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings condensed with carbocyclic rings or ring systems with only hydrogen or carbon atoms directly attached to the ring nitrogen atoms
- C07D241/40—Benzopyrazines
- C07D241/44—Benzopyrazines with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the hetero ring
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Indole Compounds (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Quinoline Compounds (AREA)
- Pyrrole Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Detergent Compositions (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Fodder In General (AREA)
- Cosmetics (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US13237387A | 1987-12-15 | 1987-12-15 | |
| US13237387 | 1987-12-15 |
Publications (4)
| Publication Number | Publication Date |
|---|---|
| FI885783A0 true FI885783A0 (fi) | 1988-12-14 |
| FI885783A FI885783A (fi) | 1989-06-16 |
| FI88295B FI88295B (fi) | 1993-01-15 |
| FI88295C FI88295C (fi) | 1993-04-26 |
Family
ID=22453720
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FI885783A FI88295C (fi) | 1987-12-15 | 1988-12-14 | Foerfarande foer framstaellning av nya, terapeutiskt anvaendbara 5-karbonylamino-4-hydroxi-n-hexanamidderivat |
Country Status (27)
| Country | Link |
|---|---|
| EP (1) | EP0321192B1 (fi) |
| JP (1) | JPH0692366B2 (fi) |
| KR (1) | KR900009022B1 (fi) |
| CN (1) | CN1025676C (fi) |
| AT (1) | ATE96433T1 (fi) |
| AU (1) | AU593181B2 (fi) |
| CA (1) | CA1314545C (fi) |
| CS (1) | CS274671B2 (fi) |
| DD (1) | DD283381A5 (fi) |
| DE (1) | DE3885252T2 (fi) |
| DK (1) | DK694888A (fi) |
| EG (1) | EG18927A (fi) |
| ES (1) | ES2059540T3 (fi) |
| FI (1) | FI88295C (fi) |
| HU (1) | HU201564B (fi) |
| IE (1) | IE61548B1 (fi) |
| IL (1) | IL88619A0 (fi) |
| MX (1) | MX14210A (fi) |
| MY (1) | MY104354A (fi) |
| NO (1) | NO172935C (fi) |
| NZ (1) | NZ227322A (fi) |
| PH (1) | PH26974A (fi) |
| PL (1) | PL152507B1 (fi) |
| PT (1) | PT89210B (fi) |
| SU (1) | SU1651786A3 (fi) |
| YU (1) | YU46686B (fi) |
| ZA (1) | ZA889307B (fi) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2638747B1 (fr) * | 1988-11-08 | 1993-12-24 | Synthelabo | Derives de phenyloxypropanolamines, leur preparation et leur application en therapeutique |
| AU622330B2 (en) * | 1989-06-23 | 1992-04-02 | Takeda Chemical Industries Ltd. | Condensed heterocyclic compounds having a nitrogen atom in the bridgehead for use as fungicides |
| DE4035846A1 (de) * | 1990-11-10 | 1991-06-06 | Kuntze Angelgeraete Dam | Angelrolle mit spule zur aufnahme der angelschnur |
| EP0966443B1 (en) * | 1997-02-26 | 2009-01-28 | Pfizer Inc. | Heteroaryl-hexanoic acid amide derivatives, their preparation and their use as selective inhibitors of mip-1-alpha binding to its ccr1 receptor |
| EP1498417A1 (en) * | 2000-02-04 | 2005-01-19 | Pfizer Products Inc. | Heterocyclic amide derivatives |
| NZ520075A (en) * | 2000-02-04 | 2004-02-27 | Pfizer Prod Inc | Heterocyclic amide derivatives |
| US20040097554A1 (en) * | 2002-10-30 | 2004-05-20 | Pfizer Inc | Heteroaryl-hexanoic acid amide derivatives as immonomodulatory agents |
| US7405210B2 (en) | 2003-05-21 | 2008-07-29 | Osi Pharmaceuticals, Inc. | Pyrrolopyridine-2-carboxylic acid amide inhibitors of glycogen phosphorylase |
| DE602004028122D1 (de) * | 2003-05-21 | 2010-08-26 | Prosidion Ltd | Pyrrolopyridin-2-carbonsäuren als hemmer der glycogenphosphorylase |
| CN108164528B (zh) * | 2018-03-31 | 2019-03-22 | 杭州巴洛特生物科技有限公司 | 一种酰胺类衍生物及其在高血压、高血脂和动脉粥样硬化中的应用 |
| CN108218865B (zh) * | 2018-03-31 | 2020-06-26 | 济南市儿童医院 | 一种酰胺类衍生物及其在心脑血管方面的应用 |
| CN108456207B (zh) * | 2018-03-31 | 2020-11-20 | 浙江药苑生物科技有限公司 | 一种酰胺类衍生物及其在心脑血管方面的应用 |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0181110A3 (en) * | 1984-10-22 | 1988-05-11 | Kissei Pharmaceutical Co. Ltd. | Histidine derivatives as renin inhibitors |
| US4727060A (en) * | 1984-11-13 | 1988-02-23 | Ciba-Geigy Corporation | Novel 5-amino-4-hydroxyvaleryl derivatives |
-
1988
- 1988-12-07 IL IL88619A patent/IL88619A0/xx not_active IP Right Cessation
- 1988-12-09 MY MYPI88001429A patent/MY104354A/en unknown
- 1988-12-12 JP JP63313642A patent/JPH0692366B2/ja not_active Expired - Lifetime
- 1988-12-12 CS CS820388A patent/CS274671B2/cs not_active IP Right Cessation
- 1988-12-12 PL PL1988276363A patent/PL152507B1/pl unknown
- 1988-12-13 CA CA000585722A patent/CA1314545C/en not_active Expired - Fee Related
- 1988-12-13 PT PT89210A patent/PT89210B/pt not_active IP Right Cessation
- 1988-12-13 ZA ZA889307A patent/ZA889307B/xx unknown
- 1988-12-14 YU YU225788A patent/YU46686B/sh unknown
- 1988-12-14 SU SU884613032A patent/SU1651786A3/ru active
- 1988-12-14 EG EG62988A patent/EG18927A/xx active
- 1988-12-14 NO NO885549A patent/NO172935C/no unknown
- 1988-12-14 ES ES88311798T patent/ES2059540T3/es not_active Expired - Lifetime
- 1988-12-14 EP EP88311798A patent/EP0321192B1/en not_active Expired - Lifetime
- 1988-12-14 NZ NZ227322A patent/NZ227322A/en unknown
- 1988-12-14 DE DE88311798T patent/DE3885252T2/de not_active Expired - Fee Related
- 1988-12-14 FI FI885783A patent/FI88295C/fi not_active IP Right Cessation
- 1988-12-14 DK DK694888A patent/DK694888A/da not_active Application Discontinuation
- 1988-12-14 DD DD88323142A patent/DD283381A5/de not_active IP Right Cessation
- 1988-12-14 CN CN88108575A patent/CN1025676C/zh not_active Expired - Fee Related
- 1988-12-14 HU HU886423A patent/HU201564B/hu not_active IP Right Cessation
- 1988-12-14 IE IE373188A patent/IE61548B1/en not_active IP Right Cessation
- 1988-12-14 AU AU26881/88A patent/AU593181B2/en not_active Ceased
- 1988-12-14 AT AT88311798T patent/ATE96433T1/de not_active IP Right Cessation
- 1988-12-14 KR KR1019880016675A patent/KR900009022B1/ko not_active IP Right Cessation
- 1988-12-15 PH PH37928A patent/PH26974A/en unknown
- 1988-12-15 MX MX1421088A patent/MX14210A/es unknown
Also Published As
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| BB | Publication of examined application | ||
| MM | Patent lapsed | ||
| MM | Patent lapsed |
Owner name: PFIZER INC. |