FI883667A - 2-/(4-piperidinyl) metyl/ -1,2,3,4-tetrahydroisokinoleinderivat, deras framstaellning och terapeutiska anvaendning. - Google Patents

2-/(4-piperidinyl) metyl/ -1,2,3,4-tetrahydroisokinoleinderivat, deras framstaellning och terapeutiska anvaendning. Download PDF

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Publication number
FI883667A
FI883667A FI883667A FI883667A FI883667A FI 883667 A FI883667 A FI 883667A FI 883667 A FI883667 A FI 883667A FI 883667 A FI883667 A FI 883667A FI 883667 A FI883667 A FI 883667A
Authority
FI
Finland
Prior art keywords
tetrahydroisokinoline
terapeutiska
anvaendning
piperidinyl
derivatives
Prior art date
Application number
FI883667A
Other languages
English (en)
Finnish (fi)
Other versions
FI883667A0 (fi
Inventor
Pascal George
Mireille Sevrin
Christian Maloizel
Original Assignee
Synthelabo
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from FR8711288A external-priority patent/FR2619110B1/fr
Priority claimed from FR8718342A external-priority patent/FR2625504B2/fr
Priority claimed from FR8805130A external-priority patent/FR2630114B2/fr
Priority claimed from FR8805129A external-priority patent/FR2630113B2/fr
Application filed by Synthelabo filed Critical Synthelabo
Publication of FI883667A0 publication Critical patent/FI883667A0/fi
Publication of FI883667A publication Critical patent/FI883667A/fi

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, cocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Pain & Pain Management (AREA)
  • Psychiatry (AREA)
  • Anesthesiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
FI883667A 1987-08-07 1988-08-05 2-/(4-piperidinyl) metyl/ -1,2,3,4-tetrahydroisokinoleinderivat, deras framstaellning och terapeutiska anvaendning. FI883667A (fi)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
FR8711288A FR2619110B1 (fr) 1987-08-07 1987-08-07 Derives de ((piperidinyl-4)methyl)-2 tetrahydro-1,2,3,4 isoquinoleine, leur preparation et leur application en therapeutique
FR8718342A FR2625504B2 (fr) 1987-08-07 1987-12-30 Derives de ((benzoyl-1 piperidinyl-4)methyl)-2 tetrahydro-1,2,3,4 isoquinoleine, leur preparation et leur application en therapeutique
FR8805130A FR2630114B2 (fr) 1987-08-07 1988-04-19 Derives de (piperidinyl-4)methyl)-2 tetrahydro-1,2,3,4 isoquinoleine, leur preparation et leur application en therapeutique
FR8805129A FR2630113B2 (fr) 1987-08-07 1988-04-19 Derives de ((piperidinyl-4)methyl)-2 tetrahydro-1,2,3,4 isoquinoleine, leur preparation et leur application en therapeutique

Publications (2)

Publication Number Publication Date
FI883667A0 FI883667A0 (fi) 1988-08-05
FI883667A true FI883667A (fi) 1989-02-08

Family

ID=27446582

Family Applications (1)

Application Number Title Priority Date Filing Date
FI883667A FI883667A (fi) 1987-08-07 1988-08-05 2-/(4-piperidinyl) metyl/ -1,2,3,4-tetrahydroisokinoleinderivat, deras framstaellning och terapeutiska anvaendning.

Country Status (10)

Country Link
US (2) US4885302A (no)
EP (1) EP0306375A1 (no)
JP (1) JPH01100167A (no)
KR (1) KR890003733A (no)
AU (1) AU598149B2 (no)
DK (1) DK437588A (no)
FI (1) FI883667A (no)
IL (1) IL87339A0 (no)
NO (1) NO883485L (no)
NZ (1) NZ225708A (no)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3717561A1 (de) * 1987-05-25 1988-12-08 Thomae Gmbh Dr K Indol-, isochinolin- und benzazepinderivate, diese verbindungen enthaltende arzneimittel und verfahren zu ihrer herstellung
IL89156A (en) * 1988-07-12 1993-05-13 Synthelabo Derivatives of 2-((4-piperidinyl) methyl)- 1,2,3,4- tetrahydroisoquinoline, their preparation and their application in therapeutics
US4963563A (en) * 1989-10-13 1990-10-16 Abbott Laboratories 6-substituted-1,2,3,4-tetrahydroisoquinolines
FR2661178B1 (fr) * 1990-04-24 1993-03-12 Synthelabo Derives de [(tetrahydro-1,2,3,4 isoquinoleinyl-2)methyl]-4 piperidinecarboxylates-1 d'alkyle, leur preparation et leur application en therapeutique.
US5258379A (en) * 1990-05-04 1993-11-02 Eli Lilly And Company Method of inhibiting gastric acid secretion with n-arylpiperazines
US5096908A (en) * 1990-05-04 1992-03-17 Eli Lilly And Company Method of inhibiting gastric acid secretion
GB9319534D0 (en) * 1993-09-22 1993-11-10 Boots Co Plc Therapeutic agents
FR2747386B1 (fr) * 1996-04-12 1998-05-15 Synthelabo Derives de 3-[(1,2,3,4-tetrahydroisoquinolein-2-yl)methyl] -8-azabicyclo [3.2.1] octane, leur preparation et leur application en therapeutique
JP2000512646A (ja) * 1996-06-25 2000-09-26 スミスクライン・ビーチャム・パブリック・リミテッド・カンパニー ５ｈｔ７受容体アンタゴニストとしてのスルホンアミド誘導体
US5912342A (en) * 1997-08-12 1999-06-15 Heinonen; Petri Compounds a containing a solid support
US6664293B2 (en) 1999-02-26 2003-12-16 Fujiwawa Pharmaceutical Co., Ltd. Amide compounds for the potentiation of cholinergic activity
AUPP891299A0 (en) * 1999-02-26 1999-03-25 Fujisawa Pharmaceutical Co., Ltd. New 6-membered cyclic compounds
AR063275A1 (es) * 2006-10-12 2009-01-14 Epix Delaware Inc Compuestos de carboxamida, una composicion farmaceutica que los comprende y su uso en la preparacion de un medicamento para el tratamiento de enfermedades mediadas por la activacion de ccr2.
WO2009076404A1 (en) * 2007-12-10 2009-06-18 Epix Delaware, Inc. Carboxamide compounds and their use as antagonists of the chemokine ccr2 receptor
WO2009076512A1 (en) * 2007-12-11 2009-06-18 Epix Delaware, Inc. Carboxamidξ compounds and their use as chemokine receptor agonists
PL2445899T3 (pl) 2009-06-26 2017-08-31 Sanofi Nowe sole fumaranowe antagonisty receptora histaminy H3
CN117157069A (zh) * 2021-02-12 2023-12-01 康复治疗公司 用于调节fgf活性的化合物、组合物和方法

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2922786A (en) * 1956-12-12 1960-01-26 Bristol Myers Co Therapeutic compounds
GB1229651A (no) * 1967-03-14 1971-04-28
FR7607M (no) * 1968-04-25 1970-01-19
GB1250719A (no) * 1969-03-19 1971-10-20
FR2426046A1 (fr) * 1978-05-18 1979-12-14 Synthelabo Derive de tetrahydro-isoquinoleine, sa preparation et son application en therapeutique
US4495354A (en) * 1982-03-29 1985-01-22 Hoffmann-La Roche Inc. Process for bicyclic diketones
IL89156A (en) * 1988-07-12 1993-05-13 Synthelabo Derivatives of 2-((4-piperidinyl) methyl)- 1,2,3,4- tetrahydroisoquinoline, their preparation and their application in therapeutics

Also Published As

Publication number Publication date
AU2047588A (en) 1989-02-09
AU598149B2 (en) 1990-06-14
IL87339A0 (en) 1989-01-31
DK437588D0 (da) 1988-08-05
NO883485D0 (no) 1988-08-05
FI883667A0 (fi) 1988-08-05
KR890003733A (ko) 1989-04-17
US4945096A (en) 1990-07-31
US4885302A (en) 1989-12-05
JPH01100167A (ja) 1989-04-18
NO883485L (no) 1989-02-08
NZ225708A (en) 1990-04-26
EP0306375A1 (fr) 1989-03-08
DK437588A (da) 1989-03-28

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Owner name: SYNTHELABO