FI882041A - Method for lyophilizing a live herpesvirus vaccine - Google Patents

Method for lyophilizing a live herpesvirus vaccine Download PDF

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Publication number
FI882041A
FI882041A FI882041A FI882041A FI882041A FI 882041 A FI882041 A FI 882041A FI 882041 A FI882041 A FI 882041A FI 882041 A FI882041 A FI 882041A FI 882041 A FI882041 A FI 882041A
Authority
FI
Finland
Prior art keywords
lyophilizing
herpesvirus vaccine
live herpesvirus
live
vaccine
Prior art date
Application number
FI882041A
Other languages
Finnish (fi)
Swedish (sv)
Other versions
FI882041A0 (en
FI94093B (en
FI94093C (en
Inventor
William J Mcaleer
Henry Z Markus
Robert Z Maigetter
Original Assignee
Merck & Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck & Co Inc filed Critical Merck & Co Inc
Publication of FI882041A0 publication Critical patent/FI882041A0/en
Publication of FI882041A publication Critical patent/FI882041A/en
Publication of FI94093B publication Critical patent/FI94093B/en
Application granted granted Critical
Publication of FI94093C publication Critical patent/FI94093C/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A61K39/245—Herpetoviridae, e.g. herpes simplex virus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A61K39/245—Herpetoviridae, e.g. herpes simplex virus
    • A61K39/25—Varicella-zoster virus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/20—Antivirals for DNA viruses
    • A61P31/22—Antivirals for DNA viruses for herpes viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/70—Multivalent vaccine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/0015—Combination vaccines based on measles-mumps-rubella
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011—Details
    • C12N2710/16011—Herpesviridae
    • C12N2710/16711—Varicellovirus, e.g. human herpesvirus 3, Varicella Zoster, pseudorabies
    • C12N2710/16734—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Virology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

A lyophilized live herpes virus vaccine that comprises from about 0.5% to about 8% moisture.
FI882041A 1987-05-04 1988-05-02 Method for lyophilizing a live herpesvirus vaccine FI94093C (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US4594087A 1987-05-04 1987-05-04
US4594087 1987-05-04

Publications (4)

Publication Number Publication Date
FI882041A0 FI882041A0 (en) 1988-05-02
FI882041A true FI882041A (en) 1988-11-05
FI94093B FI94093B (en) 1995-04-13
FI94093C FI94093C (en) 1995-07-25

Family

ID=21940663

Family Applications (1)

Application Number Title Priority Date Filing Date
FI882041A FI94093C (en) 1987-05-04 1988-05-02 Method for lyophilizing a live herpesvirus vaccine

Country Status (16)

Country Link
EP (1) EP0290197B1 (en)
JP (1) JP2643982B2 (en)
KR (1) KR960016581B1 (en)
AT (1) ATE95427T1 (en)
AU (1) AU622110B2 (en)
CA (1) CA1324956C (en)
DE (1) DE3884663T2 (en)
DK (1) DK238688A (en)
FI (1) FI94093C (en)
HK (1) HK5997A (en)
IE (1) IE61575B1 (en)
IL (1) IL86180A (en)
NO (1) NO176163C (en)
NZ (1) NZ224419A (en)
PT (1) PT87388B (en)
ZA (1) ZA883133B (en)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2000034A6 (en) * 1985-11-26 1987-10-01 Schweiz Serum & Impfinst Living vaccine against mumps and process for preparing it.
IL120202A (en) 1996-03-07 2001-03-19 Akzo Nobel Nv Container with freeze-dried vaccine components
GB9808922D0 (en) 1998-04-24 1998-06-24 Cantab Pharmaceuticals Res Ltd Virus preparations
HUP0202537A3 (en) 1999-08-24 2004-05-28 Teva Pharma A vaccine composition and method of using the same
US6592869B2 (en) 1999-08-24 2003-07-15 Teva Pharmaceutical Industries, Ltd. Vaccine composition and method of using the same
US9132184B2 (en) 2006-11-07 2015-09-15 Sanofi Pasteur Biologics, Llc Stabilization of vaccines by lyophilization
EP2699266B1 (en) * 2011-04-21 2019-06-12 Trustees Of Tufts College Compositions and methods for stabilization of active agents
EP3902529A1 (en) * 2018-12-27 2021-11-03 Amgen Inc. Lyophilized virus formulations

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5341202B2 (en) * 1974-03-12 1978-11-01
GB1481650A (en) * 1975-05-06 1977-08-03 Merck & Co Inc Chemical processes and products
US4273762A (en) * 1979-12-03 1981-06-16 Merck & Co., Inc. Lyophilization process for live viral compositions
US4859587A (en) * 1984-06-04 1989-08-22 Institut Merieux Recombinant herpes simplex viruses, vaccines and methods
ZA874625B (en) * 1986-06-30 1988-10-26 Smith Kline Rit Stabilizers for live vaccines,process for their preparation and vaccines containing them

Also Published As

Publication number Publication date
IE881248L (en) 1988-11-04
JP2643982B2 (en) 1997-08-25
DK238688A (en) 1988-11-05
KR960016581B1 (en) 1996-12-16
AU1552788A (en) 1988-11-10
NO176163B (en) 1994-11-07
IL86180A (en) 1992-08-18
HK5997A (en) 1997-01-17
NO176163C (en) 1995-02-15
PT87388A (en) 1989-05-31
EP0290197A3 (en) 1989-10-18
NO881931L (en) 1988-11-07
NZ224419A (en) 1991-03-26
PT87388B (en) 1992-08-31
DE3884663T2 (en) 1994-04-07
JPS646220A (en) 1989-01-10
AU622110B2 (en) 1992-04-02
DK238688D0 (en) 1988-05-03
ATE95427T1 (en) 1993-10-15
CA1324956C (en) 1993-12-07
DE3884663D1 (en) 1993-11-11
FI882041A0 (en) 1988-05-02
ZA883133B (en) 1988-11-08
NO881931D0 (en) 1988-05-03
KR880013575A (en) 1988-12-21
EP0290197A2 (en) 1988-11-09
EP0290197B1 (en) 1993-10-06
IL86180A0 (en) 1988-11-15
FI94093B (en) 1995-04-13
FI94093C (en) 1995-07-25
IE61575B1 (en) 1994-11-16

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Legal Events

Date Code Title Description
BB Publication of examined application
FG Patent granted

Owner name: MERCK & CO., INC.

MA Patent expired