FI880554A0 - Process for the preparation of therapeutically active pyridine-2,4- and -2,5-dicarboxylic acid derivatives - Google Patents
Process for the preparation of therapeutically active pyridine-2,4- and -2,5-dicarboxylic acid derivativesInfo
- Publication number
- FI880554A0 FI880554A0 FI880554A FI880554A FI880554A0 FI 880554 A0 FI880554 A0 FI 880554A0 FI 880554 A FI880554 A FI 880554A FI 880554 A FI880554 A FI 880554A FI 880554 A0 FI880554 A0 FI 880554A0
- Authority
- FI
- Finland
- Prior art keywords
- preparation
- dicarboxylic acid
- acid derivatives
- therapeutically active
- active pyridine
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D213/79—Acids; Esters
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D213/79—Acids; Esters
- C07D213/80—Acids; Esters in position 3
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D213/81—Amides; Imides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Immunology (AREA)
- Engineering & Computer Science (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Obesity (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Transplantation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pyridine Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19873703963 DE3703963A1 (en) | 1987-02-10 | 1987-02-10 | PYRIDINE-2,4- AND 2,, 5-DICARBONIC ACID DERIVATIVES, METHOD FOR THE PRODUCTION THEREOF, USE THEREOF, AND MEDICINAL PRODUCTS BASED ON THESE COMPOUNDS |
| DE3703963 | 1987-02-10 |
Publications (4)
| Publication Number | Publication Date |
|---|---|
| FI880554A0 true FI880554A0 (en) | 1988-02-08 |
| FI880554A FI880554A (en) | 1988-08-11 |
| FI91524B FI91524B (en) | 1994-03-31 |
| FI91524C FI91524C (en) | 1994-07-11 |
Family
ID=6320593
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FI880554A FI91524C (en) | 1987-02-10 | 1988-02-08 | Process for the preparation of therapeutically active pyridine-2,4- and -2,5-dicarboxylic acid derivatives |
Country Status (17)
| Country | Link |
|---|---|
| EP (1) | EP0278452B1 (en) |
| JP (1) | JPS63216870A (en) |
| KR (1) | KR960011371B1 (en) |
| AR (1) | AR247816A1 (en) |
| AT (1) | ATE123022T1 (en) |
| AU (1) | AU600084B2 (en) |
| DE (2) | DE3703963A1 (en) |
| DK (2) | DK168379B1 (en) |
| ES (1) | ES2073393T3 (en) |
| FI (1) | FI91524C (en) |
| HU (1) | HU207295B (en) |
| IE (1) | IE67446B1 (en) |
| IL (1) | IL85361A (en) |
| NO (1) | NO173184C (en) |
| NZ (1) | NZ223431A (en) |
| PT (1) | PT86734B (en) |
| ZA (1) | ZA88897B (en) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3707429A1 (en) * | 1987-03-07 | 1988-09-15 | Hoechst Ag | SUBSTITUTED PYRIDINE-2,4-DICARBONIC ACID DERIVATIVES, METHOD FOR THE PRODUCTION THEREOF, USE OF THE SAME AND MEDICINAL PRODUCTS BASED ON THESE COMPOUNDS |
| HU202516B (en) * | 1987-10-02 | 1991-03-28 | Egyt Gyogyszervegyeszeti Gyar | Process for producing (2-thenyl)-thiourea derivatives and yield increasing agents comprising such compounds |
| DE3924093A1 (en) | 1989-07-20 | 1991-02-07 | Hoechst Ag | N, N'-BIS (ALKOXY-ALKYL) -PYRIDINE-2,4-DICARBONESAUREDIAMIDES, METHOD FOR THE PRODUCTION AND USE THEREOF |
| DE3938805A1 (en) * | 1989-11-23 | 1991-05-29 | Hoechst Ag | PYRIDINE-2,4- AND 2,5-DICARBONIC ACID DIAMOND, METHOD FOR THE PRODUCTION AND USE THEREOF |
| DE4020570A1 (en) * | 1990-06-28 | 1992-01-02 | Hoechst Ag | 2,4- AND 2,5-SUBSTITUTED PYRIDINE-N-OXIDES, METHOD FOR THE PRODUCTION AND USE THEREOF |
| US5260323A (en) * | 1990-06-28 | 1993-11-09 | Hoechst Aktiengesellschaft | 2,4- and 2,5-substituted pyridine-N-oxides, processes for their preparation and their use |
| DE4030999A1 (en) * | 1990-10-01 | 1992-04-09 | Hoechst Ag | 4- OR 5-SUBSTITUTED PYRIDINE-2-CARBONIC ACIDS, METHOD FOR THE PRODUCTION THEREOF AND THEIR USE AS A MEDICINAL PRODUCT |
| YU9492A (en) * | 1991-02-05 | 1995-03-27 | Hoechst Ag. | 2,4- and 2,5-BIS-TETRAZOLYL pyridines and the process for their preparation |
| CA2085954A1 (en) * | 1991-12-24 | 1993-06-25 | Klaus Weidmann | Substituted pyridine n-oxides, processes for their preparation, and their use |
| DE4233124A1 (en) * | 1992-10-02 | 1994-04-07 | Hoechst Ag | Acylsulfonamido and sulfonamidopyridine-2-carboxylic acid esters and their pyridine N-oxides, processes for their preparation and their use as medicaments |
| WO1999021860A1 (en) * | 1997-10-24 | 1999-05-06 | Fibrogen, Inc. | Phenanthroline derivatives |
| KR100579792B1 (en) * | 1998-05-13 | 2006-05-12 | 동화약품공업주식회사 | Novel 2,5-pyridinedicarboxylic acid derivatives |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4093622A (en) * | 1975-05-19 | 1978-06-06 | Zoecon Corporation | Pyridine esters of cyclopropane-carboxylic acid |
| EP0123700A1 (en) * | 1983-04-27 | 1984-11-07 | Byk Gulden Lomberg Chemische Fabrik GmbH | Substituted picolinic acids, processes for their preparation, their use, and pharmaceutical preparations containing them |
| DE3432094A1 (en) * | 1984-08-31 | 1986-03-06 | Hoechst Ag, 6230 Frankfurt | ESTER OF PYRIDINE-2,4- AND -2,5-DICARBONIC ACID AS A MEDICINAL PRODUCT FOR INHIBITING PROLIN AND LYSINE HYDROXYLASE |
| US4757071A (en) * | 1984-12-14 | 1988-07-12 | Nisshin Flour Milling Co., Ltd. | 1,4-dihydropyridine derivatives, and pharmaceutical compositions containing same, useful for treating cardiovascular diseases |
| US4691018A (en) * | 1985-05-23 | 1987-09-01 | Chugai Seiyaku Kabushiki Kaisha | Pyridine derivatives and their use as anti-allergic agents |
| GB8702890D0 (en) * | 1987-02-10 | 1987-03-18 | Zyma Sa | Heterocyclic compounds |
| ATE113036T1 (en) * | 1988-08-04 | 1994-11-15 | Hoechst Ag | IMPROVED PROCESS FOR THE PRODUCTION OF N,N-BIS(ALKOXYALKYL)-PYRIDINE-2,4-DICARBONIC DIAMIDES. |
-
1987
- 1987-02-10 DE DE19873703963 patent/DE3703963A1/en not_active Withdrawn
-
1988
- 1988-02-08 NZ NZ223431A patent/NZ223431A/en unknown
- 1988-02-08 DE DE3853839T patent/DE3853839D1/en not_active Expired - Fee Related
- 1988-02-08 ES ES88101791T patent/ES2073393T3/en not_active Expired - Lifetime
- 1988-02-08 AT AT88101791T patent/ATE123022T1/en not_active IP Right Cessation
- 1988-02-08 EP EP88101791A patent/EP0278452B1/en not_active Expired - Lifetime
- 1988-02-08 FI FI880554A patent/FI91524C/en not_active IP Right Cessation
- 1988-02-08 IL IL85361A patent/IL85361A/en not_active IP Right Cessation
- 1988-02-08 AR AR88310032A patent/AR247816A1/en active
- 1988-02-09 AU AU11450/88A patent/AU600084B2/en not_active Ceased
- 1988-02-09 ZA ZA880897A patent/ZA88897B/en unknown
- 1988-02-09 JP JP63026721A patent/JPS63216870A/en active Pending
- 1988-02-09 DK DK066088A patent/DK168379B1/en active
- 1988-02-09 IE IE35088A patent/IE67446B1/en not_active IP Right Cessation
- 1988-02-09 NO NO880556A patent/NO173184C/en unknown
- 1988-02-09 PT PT86734A patent/PT86734B/en not_active IP Right Cessation
- 1988-02-09 KR KR1019880001198A patent/KR960011371B1/en active IP Right Grant
- 1988-02-10 HU HU88612A patent/HU207295B/en not_active IP Right Cessation
-
1992
- 1992-07-10 DK DK090992A patent/DK170245B1/en not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| JPS63216870A (en) | 1988-09-09 |
| DK168379B1 (en) | 1994-03-21 |
| EP0278452A2 (en) | 1988-08-17 |
| DE3703963A1 (en) | 1988-08-18 |
| HUT47249A (en) | 1989-02-28 |
| DK66088D0 (en) | 1988-02-09 |
| KR960011371B1 (en) | 1996-08-22 |
| AU1145088A (en) | 1988-08-11 |
| IL85361A (en) | 1993-01-31 |
| ES2073393T3 (en) | 1995-08-16 |
| DK170245B1 (en) | 1995-07-17 |
| ZA88897B (en) | 1988-08-09 |
| PT86734B (en) | 1992-05-29 |
| IE67446B1 (en) | 1996-04-03 |
| IE880350L (en) | 1988-08-10 |
| DK90992D0 (en) | 1992-07-10 |
| IL85361A0 (en) | 1988-07-31 |
| NO880556D0 (en) | 1988-02-09 |
| AR247816A1 (en) | 1995-04-28 |
| FI91524C (en) | 1994-07-11 |
| PT86734A (en) | 1988-03-01 |
| NO880556L (en) | 1988-08-11 |
| NO173184B (en) | 1993-08-02 |
| NO173184C (en) | 1993-11-10 |
| NZ223431A (en) | 1990-07-26 |
| DK90992A (en) | 1992-07-10 |
| EP0278452B1 (en) | 1995-05-24 |
| AU600084B2 (en) | 1990-08-02 |
| KR880009935A (en) | 1988-10-05 |
| DK66088A (en) | 1988-08-11 |
| DE3853839D1 (en) | 1995-06-29 |
| FI91524B (en) | 1994-03-31 |
| HU207295B (en) | 1993-03-29 |
| FI880554A (en) | 1988-08-11 |
| ATE123022T1 (en) | 1995-06-15 |
| EP0278452A3 (en) | 1989-10-18 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| BB | Publication of examined application | ||
| MM | Patent lapsed | ||
| MM | Patent lapsed |
Owner name: HOECHST AKTIENGESELLSCHAFT |