NO910163L - PROCEDURE FOR THE PREPARATION AND USE OF PYRIDINE-2,4- AND 2,5-DICARBOXYLIC ACID ACID (NITROXYLYCYL) AMID. - Google Patents

PROCEDURE FOR THE PREPARATION AND USE OF PYRIDINE-2,4- AND 2,5-DICARBOXYLIC ACID ACID (NITROXYLYCYL) AMID.

Info

Publication number
NO910163L
NO910163L NO91910163A NO910163A NO910163L NO 910163 L NO910163 L NO 910163L NO 91910163 A NO91910163 A NO 91910163A NO 910163 A NO910163 A NO 910163A NO 910163 L NO910163 L NO 910163L
Authority
NO
Norway
Prior art keywords
acid
nitroxylycyl
amid
pyridine
procedure
Prior art date
Application number
NO91910163A
Other languages
Norwegian (no)
Other versions
NO910163D0 (en
Inventor
Ekkehard Baader
Original Assignee
Hoechst Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Ag filed Critical Hoechst Ag
Publication of NO910163D0 publication Critical patent/NO910163D0/en
Publication of NO910163L publication Critical patent/NO910163L/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/26—Radicals substituted by halogen atoms or nitro radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/81—Amides; Imides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/81—Amides; Imides
    • C07D213/82—Amides; Imides in position 3

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Transplantation (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyridine Compounds (AREA)
NO91910163A 1990-01-16 1991-01-15 PROCEDURE FOR THE PREPARATION AND USE OF PYRIDINE-2,4- AND 2,5-DICARBOXYLIC ACID ACID (NITROXYLYCYL) AMID. NO910163L (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE4001002A DE4001002A1 (en) 1990-01-16 1990-01-16 N'N'-di:(nitroxyalkyl) pyridine-2,4- and -2,5-di:carboxamide derivs. - used as proline and lysine hydroxylase inhibitors for use a immuno:suppressive, fibro-suppressive and collagen biosynthesis inhibitors

Publications (2)

Publication Number Publication Date
NO910163D0 NO910163D0 (en) 1991-01-15
NO910163L true NO910163L (en) 1991-07-17

Family

ID=6398117

Family Applications (1)

Application Number Title Priority Date Filing Date
NO91910163A NO910163L (en) 1990-01-16 1991-01-15 PROCEDURE FOR THE PREPARATION AND USE OF PYRIDINE-2,4- AND 2,5-DICARBOXYLIC ACID ACID (NITROXYLYCYL) AMID.

Country Status (19)

Country Link
EP (1) EP0438795A1 (en)
JP (1) JPH04330060A (en)
KR (1) KR910014352A (en)
CN (1) CN1053606A (en)
AU (1) AU631285B2 (en)
BR (1) BR9100159A (en)
CA (1) CA2034206A1 (en)
CS (1) CS7591A2 (en)
DE (1) DE4001002A1 (en)
FI (1) FI910177A (en)
HU (1) HUT59102A (en)
IE (1) IE910126A1 (en)
IL (1) IL96941A0 (en)
MA (1) MA22041A1 (en)
MX (1) MX24143A (en)
NO (1) NO910163L (en)
NZ (1) NZ236766A (en)
PT (1) PT96493A (en)
ZA (1) ZA91291B (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4020570A1 (en) 1990-06-28 1992-01-02 Hoechst Ag 2,4- AND 2,5-SUBSTITUTED PYRIDINE-N-OXIDES, METHOD FOR THE PRODUCTION AND USE THEREOF
YU9492A (en) * 1991-02-05 1995-03-27 Hoechst Ag. 2,4- and 2,5-BIS-TETRAZOLYL pyridines and the process for their preparation
EP0533130A1 (en) * 1991-09-19 1993-03-24 Hoechst Aktiengesellschaft 2-Hydroxymethylpyridines, the corresponding pyridine-N-oxides and derivatives thereof, process for their preparation and their use
EP0541042A1 (en) * 1991-11-05 1993-05-12 Hoechst Aktiengesellschaft 2,4- and 2,5-pyridine-dicarboxylic acid derivatives, process for their preparation and their use

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK145608C (en) * 1976-04-02 1983-07-11 Chugai Pharmaceutical Co Ltd ANALOGY PROCEDURE FOR PREPARING THE NICKETIC ACID ESTER OF N- (2-HYDROXYETHYL) NICOTINAMIDE
DE3432094A1 (en) * 1984-08-31 1986-03-06 Hoechst Ag, 6230 Frankfurt ESTER OF PYRIDINE-2,4- AND -2,5-DICARBONIC ACID AS A MEDICINAL PRODUCT FOR INHIBITING PROLIN AND LYSINE HYDROXYLASE
DE3703959A1 (en) * 1987-02-10 1988-08-18 Hoechst Ag PYRIDINE-2,4- AND 2,5-DICARBONIC ACID AMIDES, METHOD FOR THE PRODUCTION THEREOF, USE OF THE SAME AND MEDICINAL PRODUCTS BASED ON THESE COMPOUNDS

Also Published As

Publication number Publication date
FI910177A0 (en) 1991-01-14
HUT59102A (en) 1992-04-28
AU6936691A (en) 1991-07-18
PT96493A (en) 1991-10-15
MX24143A (en) 1993-05-01
EP0438795A1 (en) 1991-07-31
BR9100159A (en) 1991-10-22
IL96941A0 (en) 1992-03-29
CN1053606A (en) 1991-08-07
NZ236766A (en) 1993-08-26
MA22041A1 (en) 1991-10-01
CS7591A2 (en) 1991-09-15
FI910177A (en) 1991-07-17
DE4001002A1 (en) 1991-07-18
AU631285B2 (en) 1992-11-19
KR910014352A (en) 1991-08-31
IE910126A1 (en) 1991-07-17
NO910163D0 (en) 1991-01-15
HU910109D0 (en) 1991-08-28
CA2034206A1 (en) 1991-07-17
JPH04330060A (en) 1992-11-18
ZA91291B (en) 1991-09-25

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