FI871360A0 - NYA FENOXIALKYLKARBOXYLSYRADERIVAT FOERFARANDE FOER DERAS FRAMSTAELLNING OCH LAEKEMEDEL INNEHAOLLANDE DESSA FOERENINGAR. - Google Patents

NYA FENOXIALKYLKARBOXYLSYRADERIVAT FOERFARANDE FOER DERAS FRAMSTAELLNING OCH LAEKEMEDEL INNEHAOLLANDE DESSA FOERENINGAR.

Info

Publication number
FI871360A0
FI871360A0 FI871360A FI871360A FI871360A0 FI 871360 A0 FI871360 A0 FI 871360A0 FI 871360 A FI871360 A FI 871360A FI 871360 A FI871360 A FI 871360A FI 871360 A0 FI871360 A0 FI 871360A0
Authority
FI
Finland
Prior art keywords
group
fenoxialkylkarboxylsyraderivat
laekemedel
nya
alkyl
Prior art date
Application number
FI871360A
Other languages
Finnish (fi)
Other versions
FI871360A (en
Inventor
Ernst-Christian Witte
Hans Peter Wolff
Karlheinz Stegmeier
Johannes Pill
Original Assignee
Boehringer Mannheim Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Mannheim Gmbh filed Critical Boehringer Mannheim Gmbh
Publication of FI871360A0 publication Critical patent/FI871360A0/en
Publication of FI871360A publication Critical patent/FI871360A/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C307/00—Amides of sulfuric acids, i.e. compounds having singly-bound oxygen atoms of sulfate groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
    • C07C307/02—Monoamides of sulfuric acids or esters thereof, e.g. sulfamic acids

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Cardiology (AREA)
  • Obesity (AREA)
  • Pulmonology (AREA)
  • Epidemiology (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Professional, Industrial, Or Sporting Protective Garments (AREA)
  • Detergent Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Phenoxyalkylcarboxylic acid derivatives of the formula I <IMAGE> in which the sulfonylaminoalkyl group is in the ortho- or the meta-position to the phenoxyalkylcarboxylic acid group and in which R1 denotes an aryl group, aralkyl group or an aralkenyl group whose aryl radical can in each case be optionally mono- or polysubstituted by halogen, cyano, alkyl, trifluoromethyl, alkoxy, hydroxyl, nitro, amino, alkylamino, dialkylamino, acylamino, acyl, azido or can be substituted by phenyl which is optionally substituted by halogen, cyano, alkyl, trifluoromethyl or alkoxy, R2 represents hydrogen, an alkyl group, aralkyl group or an acyl group, R3 and R4, which can be identical or different, denote hydrogen or a lower alkyl group and n denotes the numbers 1-3, and their physiologically acceptable salts, esters and amides have platelet aggregation-inhibiting and/or hypolipidaemic action.
FI871360A 1986-03-29 1987-03-27 NYA FENOXIALKYLKARBOXYLSYRADERIVAT FOERFARANDE FOER DERAS FRAMSTAELLNING OCH LAEKEMEDEL INNEHAOLLANDE DESSA FOERENINGAR. FI871360A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19863610643 DE3610643A1 (en) 1986-03-29 1986-03-29 NEW PHENOXYALKYL CARBONIC ACID DERIVATIVES, METHOD FOR THE PRODUCTION THEREOF AND MEDICINAL PRODUCTS CONTAINING THESE COMPOUNDS

Publications (2)

Publication Number Publication Date
FI871360A0 true FI871360A0 (en) 1987-03-27
FI871360A FI871360A (en) 1987-09-30

Family

ID=6297529

Family Applications (1)

Application Number Title Priority Date Filing Date
FI871360A FI871360A (en) 1986-03-29 1987-03-27 NYA FENOXIALKYLKARBOXYLSYRADERIVAT FOERFARANDE FOER DERAS FRAMSTAELLNING OCH LAEKEMEDEL INNEHAOLLANDE DESSA FOERENINGAR.

Country Status (15)

Country Link
EP (1) EP0239907B1 (en)
JP (1) JPS62238259A (en)
AT (1) ATE67483T1 (en)
AU (1) AU582043B2 (en)
CS (1) CS271469B2 (en)
DD (1) DD263287A5 (en)
DE (2) DE3610643A1 (en)
DK (1) DK155387A (en)
ES (1) ES2037676T3 (en)
FI (1) FI871360A (en)
GR (1) GR3003100T3 (en)
HU (1) HU197879B (en)
IL (1) IL82039A0 (en)
PT (1) PT84572B (en)
ZA (1) ZA872254B (en)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8528398D0 (en) * 1985-11-19 1985-12-24 Glaxo Group Ltd Chemical compounds
JPS62277347A (en) * 1986-02-25 1987-12-02 Microbial Chem Res Found Novel performed chemical mediator aabustatin analog compound
IL83230A (en) * 1986-08-06 1992-06-21 Tanabe Seiyaku Co Phenoxyacetic acid derivatives,their preparation and pharmaceutical compositions containing them
AT396235B (en) * 1987-02-06 1993-07-26 Tanabe Seiyaku Co New sulphonyl amino phenoxy acetic acid cpds. - are platelet agglutination inhibitors useful for treating e.g. cerebral thrombosis and pulmonary embolism
GB8708233D0 (en) * 1987-04-07 1987-05-13 Smith Kline French Lab Pharmaceutically active compounds
JPH068275B2 (en) * 1988-02-04 1994-02-02 田辺製薬株式会社 Phenoxyacetic acid derivative
EP0325245B1 (en) * 1988-01-19 1993-10-20 Tanabe Seiyaku Co., Ltd. Phenoxyacetic acid derivatives, preparation thereof, pharmaceutical compositions comprising them and use
JPH068274B2 (en) * 1988-01-19 1994-02-02 田辺製薬株式会社 Phenoxyacetic acid derivative
DE3829431A1 (en) * 1988-08-31 1990-03-01 Boehringer Mannheim Gmbh SULPHONAMID WITH TETRAZOLYL RESIDUE, METHOD FOR THE PRODUCTION THEREOF AND MEDICINAL PRODUCTS
US5173500A (en) * 1988-08-31 1992-12-22 Boehringer Mannheim Gmbh Pharmaceutical compositions and methods of sulphonamides containing a tetrazolyl radical
DE3829455A1 (en) * 1988-08-31 1990-03-15 Boehringer Mannheim Gmbh SULFONAMIDOALKYL-CYCLOHEXAN COMPOUNDS, METHOD FOR THE PRODUCTION THEREOF AND MEDICINAL PRODUCTS
US5280043A (en) * 1988-10-10 1994-01-18 Smith Kline & French Laboratories Ltd. Sulphonamido containing phenylalkanoic acids as thromboxane A2 antagonists
US5256812A (en) * 1989-01-31 1993-10-26 Hoffmann-La Roche Inc. Carboxamides and sulfonamides
US5084466A (en) * 1989-01-31 1992-01-28 Hoffmann-La Roche Inc. Novel carboxamide pyridine compounds which have useful pharmaceutical utility
DE3942923A1 (en) * 1989-12-23 1991-06-27 Boehringer Mannheim Gmbh NEW PHENOXYALKYL CARBONIC ACID AMIDES, METHOD FOR THE PRODUCTION THEREOF AND MEDICINAL PRODUCTS CONTAINING THESE COMPOUNDS
JPH05125038A (en) * 1991-03-07 1993-05-21 Tanabe Seiyaku Co Ltd Phenoxyalkanoic acid derivative and its production
CA2092152A1 (en) * 1992-03-23 1993-09-24 Azuma Igarashi Phenoxyacetic acid compounds and medical preparations containing them

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2809377A1 (en) * 1978-03-04 1979-09-13 Boehringer Mannheim Gmbh PHENOXYALKYL CARBONIC ACID DERIVATIVES, METHOD FOR THE PRODUCTION THEREOF, AND MEDICINAL PRODUCTS CONTAINING THESE COMPOUNDS
GB8528398D0 (en) * 1985-11-19 1985-12-24 Glaxo Group Ltd Chemical compounds

Also Published As

Publication number Publication date
DD263287A5 (en) 1988-12-28
CS271469B2 (en) 1990-10-12
CS207387A2 (en) 1990-02-12
EP0239907A1 (en) 1987-10-07
FI871360A (en) 1987-09-30
GR3003100T3 (en) 1993-02-17
IL82039A0 (en) 1987-10-20
ZA872254B (en) 1987-11-25
DK155387D0 (en) 1987-03-26
HUT43559A (en) 1987-11-30
PT84572B (en) 1989-11-30
ATE67483T1 (en) 1991-10-15
AU582043B2 (en) 1989-03-09
DE3610643A1 (en) 1987-10-01
AU7072387A (en) 1987-10-15
PT84572A (en) 1987-04-01
ES2037676T3 (en) 1993-07-01
JPS62238259A (en) 1987-10-19
HU197879B (en) 1989-06-28
DE3773026D1 (en) 1991-10-24
EP0239907B1 (en) 1991-09-18
DK155387A (en) 1987-09-30

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Legal Events

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Owner name: BOEHRINGER MANNHEIM GMBH