FI865317A0 - 1-karbakefalosporin-antibiotika. - Google Patents

1-karbakefalosporin-antibiotika.

Info

Publication number
FI865317A0
FI865317A0 FI865317A FI865317A FI865317A0 FI 865317 A0 FI865317 A0 FI 865317A0 FI 865317 A FI865317 A FI 865317A FI 865317 A FI865317 A FI 865317A FI 865317 A0 FI865317 A0 FI 865317A0
Authority
FI
Finland
Prior art keywords
karbakefalosporin
antibiotika
Prior art date
Application number
FI865317A
Other languages
English (en)
Other versions
FI865317A (fi
FI83959C (fi
FI83959B (fi
Inventor
John Edwin Munroe
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of FI865317A0 publication Critical patent/FI865317A0/fi
Publication of FI865317A publication Critical patent/FI865317A/fi
Application granted granted Critical
Publication of FI83959B publication Critical patent/FI83959B/fi
Publication of FI83959C publication Critical patent/FI83959C/fi

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D463/00—Heterocyclic compounds containing 1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbacephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D463/10—Heterocyclic compounds containing 1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbacephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2
    • C07D463/14—Heterocyclic compounds containing 1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbacephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 with hetero atoms directly attached in position 7
    • C07D463/16—Nitrogen atoms
    • C07D463/18—Nitrogen atoms further acylated by radicals derived from carboxylic acids or by nitrogen or sulfur analogues thereof
    • C07D463/20—Nitrogen atoms further acylated by radicals derived from carboxylic acids or by nitrogen or sulfur analogues thereof with the acylating radicals further substituted by hetero atoms or by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D463/00—Heterocyclic compounds containing 1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbacephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D463/10—Heterocyclic compounds containing 1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbacephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2
    • C07D463/14—Heterocyclic compounds containing 1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbacephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 with hetero atoms directly attached in position 7
    • C07D463/16—Nitrogen atoms
    • C07D463/18—Nitrogen atoms further acylated by radicals derived from carboxylic acids or by nitrogen or sulfur analogues thereof
    • C07D463/20—Nitrogen atoms further acylated by radicals derived from carboxylic acids or by nitrogen or sulfur analogues thereof with the acylating radicals further substituted by hetero atoms or by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • C07D463/22—Nitrogen atoms further acylated by radicals derived from carboxylic acids or by nitrogen or sulfur analogues thereof with the acylating radicals further substituted by hetero atoms or by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen further substituted by nitrogen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Cephalosporin Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
FI865317A 1985-12-30 1986-12-29 Foerfarande foer framstaellning av antibiotiskt aktiva 1-karba-(1-detia) cefalosporinderivat. FI83959C (fi)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US81494385A 1985-12-30 1985-12-30
US81494385 1985-12-30

Publications (4)

Publication Number Publication Date
FI865317A0 true FI865317A0 (fi) 1986-12-29
FI865317A FI865317A (fi) 1987-07-01
FI83959B FI83959B (fi) 1991-06-14
FI83959C FI83959C (fi) 1991-09-25

Family

ID=25216415

Family Applications (1)

Application Number Title Priority Date Filing Date
FI865317A FI83959C (fi) 1985-12-30 1986-12-29 Foerfarande foer framstaellning av antibiotiskt aktiva 1-karba-(1-detia) cefalosporinderivat.

Country Status (21)

Country Link
US (2) US4791106A (fi)
EP (1) EP0232623B1 (fi)
JP (2) JPH0791291B2 (fi)
KR (1) KR900000267B1 (fi)
CN (1) CN1020340C (fi)
AR (1) AR245126A1 (fi)
AT (1) ATE86992T1 (fi)
AU (1) AU598504B2 (fi)
CA (1) CA1274519A (fi)
DE (1) DE3688066T2 (fi)
DK (1) DK631386A (fi)
EG (1) EG18119A (fi)
ES (1) ES2053452T3 (fi)
FI (1) FI83959C (fi)
HU (1) HU204269B (fi)
IE (1) IE59727B1 (fi)
IL (1) IL81115A (fi)
PH (1) PH25644A (fi)
PT (1) PT84031B (fi)
SU (2) SU1575940A3 (fi)
ZA (1) ZA869747B (fi)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4673737A (en) * 1985-08-02 1987-06-16 Harvard University 7-acylamino-(or 7-amino)-3-trifluoromethylsulfonyloxy-1-carba(1-dethia)-3-cephem-4-carboxylic acids and esters thereof
JPH0791291B2 (ja) * 1985-12-30 1995-10-04 イ−ライ・リリ−・アンド・カンパニ− １−カルバセフアロスポリン抗生物質
ES2147721T3 (es) 1990-04-18 2000-10-01 Procter & Gamble Pharma Quinolonil lactamas antimicrobianas.
NZ247464A (en) * 1992-04-24 1994-12-22 Lilly Co Eli Preparation of 2-amino-acetamidocephalosporin derivatives, the 2-acetamido group substituted in the 2-position by a c5-6 cyclic hydrocarbon or a c5-heterocycle
US5750681A (en) * 1995-06-19 1998-05-12 University Of Notre Dame Du Lac Bicyclic beta-lactams and process therefor

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4226866A (en) * 1972-11-06 1980-10-07 Merck & Co., Inc. Novel antibiotic analogues of cephalosporins
SE401549B (sv) * 1977-01-18 1978-05-16 Skf Ab Dempningsanordning for glidlager
NO790956L (no) * 1978-03-25 1979-09-26 Kyowa Hakko Kogyo Kk Analogifremgangsmaate til fremstilling av cefalosporinanaloge eller farmasoeytisk akseptable salter derav
US4275207A (en) * 1978-08-14 1981-06-23 Merck & Co., Inc. Process for preparing 7-(1-hydroxyethyl)-3-(2-aminoethylthio)-1-carbadethiaceph-3-em-3-carboxylic acid and intermediate therefor
NO155548C (no) * 1979-02-10 1987-04-15 Kyowa Hakko Kogyo Kk Fremgangsmaate til fremstilling av optisk aktive cefalosporin-analoger.
EP0112481A1 (en) * 1982-11-12 1984-07-04 Kyowa Hakko Kogyo Co., Ltd Beta-lactam compound
JPS60174787A (ja) * 1984-02-21 1985-09-09 Kyowa Hakko Kogyo Co Ltd ３位置換カルバセフエム化合物
JPH0791291B2 (ja) * 1985-12-30 1995-10-04 イ−ライ・リリ−・アンド・カンパニ− １−カルバセフアロスポリン抗生物質

Also Published As

Publication number Publication date
KR870006049A (ko) 1987-07-08
ES2053452T3 (es) 1994-08-01
EP0232623B1 (en) 1993-03-17
ZA869747B (en) 1988-08-31
IL81115A (en) 1992-05-25
EP0232623A1 (en) 1987-08-19
ATE86992T1 (de) 1993-04-15
EG18119A (en) 1993-06-30
JP2634386B2 (ja) 1997-07-23
JPS62158282A (ja) 1987-07-14
AU598504B2 (en) 1990-06-28
IL81115A0 (en) 1987-03-31
HU204269B (en) 1991-12-30
CA1274519A (en) 1990-09-25
SU1683499A3 (ru) 1991-10-07
DK631386A (da) 1987-08-20
PT84031A (en) 1987-01-01
CN1020340C (zh) 1993-04-21
US4892942A (en) 1990-01-09
FI865317A (fi) 1987-07-01
IE863407L (en) 1987-06-30
IE59727B1 (en) 1994-03-23
FI83959C (fi) 1991-09-25
SU1575940A3 (ru) 1990-06-30
AR245126A1 (es) 1993-12-30
US4791106A (en) 1988-12-13
PT84031B (pt) 1989-07-31
DE3688066T2 (de) 1993-07-22
HUT43851A (en) 1987-12-28
DE3688066D1 (de) 1993-04-22
KR900000267B1 (ko) 1990-01-24
JPH0791291B2 (ja) 1995-10-04
PH25644A (en) 1991-08-21
JPH0873457A (ja) 1996-03-19
CN86108961A (zh) 1987-08-05
AU6705586A (en) 1987-07-02
DK631386D0 (da) 1986-12-29
FI83959B (fi) 1991-06-14

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Legal Events

Date Code Title Description
MM Patent lapsed
MM Patent lapsed

Owner name: ELI LILLY AND COMPANY