FI861923A0 - COMPOSITION, VILKA ANVAENDS VID FRAMSTAELLNING AV MICROPARTIKLAR SOM SKALL EXTRUDERAS OCH VILKA AOSTADKOMMER ETT FOERLAENGT FRIGIVANDE AV ETT BIOLOGISKT AKTIVT MEDEL, OCH DE SAOLUNDA ERHAOLLNA MIKROPARTIKLAR. - Google Patents

COMPOSITION, VILKA ANVAENDS VID FRAMSTAELLNING AV MICROPARTIKLAR SOM SKALL EXTRUDERAS OCH VILKA AOSTADKOMMER ETT FOERLAENGT FRIGIVANDE AV ETT BIOLOGISKT AKTIVT MEDEL, OCH DE SAOLUNDA ERHAOLLNA MIKROPARTIKLAR.

Info

Publication number
FI861923A0
FI861923A0 FI861923A FI861923A FI861923A0 FI 861923 A0 FI861923 A0 FI 861923A0 FI 861923 A FI861923 A FI 861923A FI 861923 A FI861923 A FI 861923A FI 861923 A0 FI861923 A0 FI 861923A0
Authority
FI
Finland
Prior art keywords
ett
vilka
och
composition
saolunda
Prior art date
Application number
FI861923A
Other languages
Finnish (fi)
Other versions
FI861923A (en
Inventor
Jehan-Yves Drouin
Michel Veillard
Original Assignee
Rhone Poulenc Sante
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Rhone Poulenc Sante filed Critical Rhone Poulenc Sante
Publication of FI861923A0 publication Critical patent/FI861923A0/en
Publication of FI861923A publication Critical patent/FI861923A/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1641—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poloxamers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1617—Organic compounds, e.g. phospholipids, fats
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1635—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1652—Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin

Landscapes

  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Manufacturing Of Micro-Capsules (AREA)
  • Peptides Or Proteins (AREA)
  • Processes Of Treating Macromolecular Substances (AREA)

Abstract

1. A composition for the preparation by extrusion of microparticles permitting a prolonged release of a biologically active substance, which composition consists of a biologically active substance, one or more non-hydrophilic polymers and from 10 to 40% by weight either of a mixture of at least two lipid excipients one of which has the property of dissolving or gelling the polymer or polymers and the other has lubricating properties or of a lipid excipient having both the property of dissolving or gelling the polymer or polymers and lubricating properties, and, if appropriate, one or more additives chosen from diluents and antistatic agents.
FI861923A 1985-05-09 1986-05-08 COMPOSITION, VILKA ANVAENDS VID FRAMSTAELLNING AV MICROPARTIKLAR SOM SKALL EXTRUDERAS OCH VILKA AOSTADKOMMER ETT FOERLAENGT FRIGIVANDE AV ETT BIOLOGISKT AKTIVT MEDEL, OCH DE SAOLUNDA ERHAOLLNA MIKROPARTIKLAR. FI861923A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR8507013A FR2581541B1 (en) 1985-05-09 1985-05-09 NOVEL PHARMACEUTICAL COMPOSITIONS FOR THE EXTENDED RELEASE OF AN ACTIVE INGREDIENT AND THEIR PREPARATION METHOD

Publications (2)

Publication Number Publication Date
FI861923A0 true FI861923A0 (en) 1986-05-08
FI861923A FI861923A (en) 1986-11-10

Family

ID=9319093

Family Applications (1)

Application Number Title Priority Date Filing Date
FI861923A FI861923A (en) 1985-05-09 1986-05-08 COMPOSITION, VILKA ANVAENDS VID FRAMSTAELLNING AV MICROPARTIKLAR SOM SKALL EXTRUDERAS OCH VILKA AOSTADKOMMER ETT FOERLAENGT FRIGIVANDE AV ETT BIOLOGISKT AKTIVT MEDEL, OCH DE SAOLUNDA ERHAOLLNA MIKROPARTIKLAR.

Country Status (14)

Country Link
EP (1) EP0204596B1 (en)
JP (1) JPS61260029A (en)
KR (1) KR860008774A (en)
AT (1) ATE45283T1 (en)
AU (1) AU579012B2 (en)
CA (1) CA1266841A (en)
DE (1) DE3664867D1 (en)
DK (1) DK217286A (en)
ES (1) ES8802206A1 (en)
FI (1) FI861923A (en)
FR (1) FR2581541B1 (en)
MA (1) MA20670A1 (en)
NZ (1) NZ216082A (en)
ZA (1) ZA863431B (en)

Families Citing this family (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5198226A (en) * 1986-01-30 1993-03-30 Syntex (U.S.A.) Inc. Long acting nicardipine hydrochloride formulation
US4940556A (en) * 1986-01-30 1990-07-10 Syntex (U.S.A.) Inc. Method of preparing long acting formulation
IL81419A0 (en) * 1986-01-30 1987-08-31 Syntex Inc Long acting sustained release pharmaceutical compositions containing dihydropyridines and their preparation
SE457326B (en) * 1986-02-14 1988-12-19 Lejus Medical Ab PROCEDURES FOR PREPARING A QUICK SUBSTANTIAL CANDLES CONTAINING BLA MICROCRISTALLIN CELLULOSA
DE3612212A1 (en) * 1986-04-11 1987-10-15 Basf Ag METHOD FOR PRODUCING SOLID PHARMACEUTICAL FORMS
HU202753B (en) * 1986-06-21 1991-04-29 Sandoz Ag Process for producing retard pharmaceutical compositions containing cetotiphene
FR2634376B1 (en) 1988-07-21 1992-04-17 Farmalyoc NOVEL SOLID AND POROUS UNIT FORM COMPRISING MICROPARTICLES AND / OR NANOPARTICLES, AS WELL AS ITS PREPARATION
FR2663818B1 (en) * 1990-06-29 1993-07-09 Rhone Poulenc Nutrition Animale PROCESS FOR THE PREPARATION OF GRANULES OF ACTIVE PRINCIPLES BY EXTRUSION.
DE4021678C2 (en) * 1990-07-07 1994-07-07 Merz & Co Gmbh & Co Process for the preparation of small-sized shaped articles with a high etofibrate content and controlled release of active ingredient, their use and existing orally administrable administration forms
DE4031881C2 (en) * 1990-10-08 1994-02-24 Sanol Arznei Schwarz Gmbh Solvent-free, oral sustained-release pharmaceutical preparation and process for its preparation
WO1993007859A1 (en) * 1991-10-23 1993-04-29 Warner-Lambert Company Novel pharmaceutical pellets and process for their production
EP0641195B1 (en) * 1992-05-22 1996-04-10 Gödecke Aktiengesellschaft Process for preparing delayed-action medicinal compositions
US5700410A (en) * 1992-10-16 1997-12-23 Nippon Shinyaku Co., Ltd. Method of manufacturing wax matrices
ES2061394B1 (en) * 1993-02-05 1995-06-16 Robert S A Lab MANUFACTURING PROCEDURE OF A POTASSIC CITRATE GRANULATE WITH DELAYED ASSIGNMENT.
FR2702968B1 (en) * 1993-03-23 1995-06-23 Lafon Labor Process for the preparation of particles containing an active ingredient by extrusion and lyophilization.
US5843347A (en) * 1993-03-23 1998-12-01 Laboratoire L. Lafon Extrusion and freeze-drying method for preparing particles containing an active ingredient
BE1006990A5 (en) * 1993-04-22 1995-02-07 Univ Gent METHOD AND COMPOSITION TO MAKE AN ACTIVE INGREDIENT IN A solid dosage form.
FR2710500B1 (en) * 1993-09-27 1995-12-01 Virbac Laboratoires Composition and system for oral administration for animals, their preparation process and their applications.
DE4422881A1 (en) * 1993-10-25 1995-04-27 Bayer Ag Colloidally dispersible drug formulations
ES2199981T3 (en) * 1994-02-16 2004-03-01 Abbott Laboratories MODE OF PREPARATION OF PHARMACEUTICAL FORMULATIONS OF FINE PARTICLES.
DE4413350A1 (en) * 1994-04-18 1995-10-19 Basf Ag Retard matrix pellets and process for their production
GB9422154D0 (en) 1994-11-03 1994-12-21 Euro Celtique Sa Pharmaceutical compositions and method of producing the same
US5965161A (en) * 1994-11-04 1999-10-12 Euro-Celtique, S.A. Extruded multi-particulates
DE29502547U1 (en) * 1995-02-16 1995-03-30 Röhm GmbH, 64293 Darmstadt Thermoplastic coating and binding agent for pharmaceutical forms
DE19531277A1 (en) * 1995-08-25 1997-02-27 Basf Ag Use of lipids as an aid in the production of solid dosage forms by the melt extrusion process
DE19539363A1 (en) * 1995-10-23 1997-04-24 Basf Ag Process for the production of solid dosage forms
GB2344520A (en) * 1998-12-08 2000-06-14 Phares Pharm Res Nv Pharmaceutical carriers comprising lipids and polymers
DE10029201A1 (en) 2000-06-19 2001-12-20 Basf Ag Retarded release oral dosage form, obtained by granulating mixture containing active agent and polyvinyl acetate-polyvinyl pyrrolidone mixture below the melting temperature
US6733709B2 (en) 2000-08-03 2004-05-11 The Procter & Gamble Company Methods and apparatus for producing granular compositions
US20200093744A1 (en) * 2017-01-30 2020-03-26 Case Western Reserve University Polymer constructs for controlled release of guest agents

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3146167A (en) * 1961-10-05 1964-08-25 Smith Kline French Lab Method of preparing sustained release pellets and products thereof
US3247065A (en) * 1963-10-14 1966-04-19 Hoffmann La Roche Free-flowing coated ascorbic acid
US3965256A (en) * 1972-05-16 1976-06-22 Synergistics Slow release pharmaceutical compositions
DE3024416C2 (en) * 1980-06-28 1982-04-15 Gödecke AG, 1000 Berlin Process for the production of medicaments with sustained release of active substances
FR2515035A1 (en) * 1981-10-26 1983-04-29 Rhone Poulenc Sante NEW SOLID GALENIC FORM FOR ORAL ADMINISTRATION AND METHOD OF MANUFACTURING THE SAME
IT1200217B (en) * 1986-09-30 1989-01-05 Valducci Roberto MEMBRANE FOR PHARMACEUTICAL AND INDUSTRIAL USE

Also Published As

Publication number Publication date
ATE45283T1 (en) 1989-08-15
KR860008774A (en) 1986-12-18
ZA863431B (en) 1986-12-30
ES554821A0 (en) 1988-04-16
AU579012B2 (en) 1988-11-10
DK217286A (en) 1986-11-10
NZ216082A (en) 1989-01-06
ES8802206A1 (en) 1988-04-16
JPS61260029A (en) 1986-11-18
FR2581541B1 (en) 1988-05-20
MA20670A1 (en) 1986-12-31
EP0204596A1 (en) 1986-12-10
FR2581541A1 (en) 1986-11-14
DK217286D0 (en) 1986-05-09
DE3664867D1 (en) 1989-09-14
EP0204596B1 (en) 1989-08-09
AU5722486A (en) 1986-11-13
FI861923A (en) 1986-11-10
CA1266841A (en) 1990-03-20

Similar Documents

Publication Publication Date Title
FI861923A (en) COMPOSITION, VILKA ANVAENDS VID FRAMSTAELLNING AV MICROPARTIKLAR SOM SKALL EXTRUDERAS OCH VILKA AOSTADKOMMER ETT FOERLAENGT FRIGIVANDE AV ETT BIOLOGISKT AKTIVT MEDEL, OCH DE SAOLUNDA ERHAOLLNA MIKROPARTIKLAR.
BR9910016A (en) Microspheres, their preparation process, and pharmaceutical compositions
BR9712372A (en) Process for preparing nanoparticles formed by a statistically polymer, nanoparticles formed by a polymer of at least one compound, and pharmaceutical composition.
FI884604A0 (en) IMPLANTERBAR, BIOLOGISKT NEDBRYTBART AKTIVMEDELS FRIGIVNINGSSYSTEM.
DK0544144T3 (en) Solid pharmaceutical retardant form
FI92014C (en) Fixed release solid matrix for use as a carrier for a drug
FR2545354B1 (en) PHARMACEUTICAL COMPOSITION FOR PARENTERAL ADMINISTRATION BASED ON NIMODIPIN AND METHOD FOR THE PREPARATION THEREOF
FI870616A (en) Polymer compositions which are used as light-degradable and heat-stabilized films
ATE13545T1 (en) STABILIZER COMPOSITIONS, HALOGEN-CONTAINING POLYMER COMPOSITIONS INCLUDING THEM, AND SHAPED ARTICLES INCLUDING THE POLYMER COMPOSITIONS.
PT89055A (en) PROCESS FOR THE PREPARATION OF A LIBERTACAO SUSTAINED ADMINISTRATION SYSTEM FOR CALCIUM CHANNEL BLOCKERS BASED ON REPLACED DI-HYDROPYRIDINES
ES2039377T3 (en) A SUPPOSITORY.
ES2054268T3 (en) POLYMERIC ADDITIVES.
ATE135696T1 (en) DIAMINO-S-TRIAZINONE DERIVATIVES AND SELF-EXTINGUISHING POLYMER COMPOSITIONS CONTAINING SAME
FR2756826B1 (en) NOVEL SUBSTITUTED TETRAHYDROPYRIDINIC DERIVATIVES, THEIR PREPARATION PROCESS AND THE PHARMACEUTICAL COMPOSITIONS CONTAINING THEM
FI912269A (en) 3'-DEAMINO - 4'DEOXI - 4'-AMINO-8-FLUORANTRACYCLINER AND FRAMSTAELLNINGSFOERFARANDEN FOER DESSA.
ES2121070T3 (en) 3,9-BIS (DIALQUILAMINO) -2,4,8,10-TETRAOXA-3,9-DIFOSFAESPIRO (5,5) -UNDECANOS AND STABILIZED COMPOSITIONS.
ATE84720T1 (en) USE OF ADENOSIN DERIVATIVES FOR THE MANUFACTURE OF PHARMACEUTICALS WITH IMMUNOSTIMULATING EFFECTS.
MC2102A1 (en) APPLICATION OF MIXED MICELLES
FI873145A (en) NYA TETRACYCLISKA INDOLDERIVAT.
ES2062072T3 (en) CHLOROFIBERS WITH A PERMANENT ANTISEPTIC CHARACTER AND PROCEDURE TO OBTAIN THEM.
KR920006354A (en) Pyrazoloquinoline derivatives
TH3543A (en) New benzimidazole derivative
ES2125970T3 (en) COMPOSITIONS INHIBITING THE TRANSFER OF DYE INCLUDING POLYMER DISPERSING AGENTS.

Legal Events

Date Code Title Description
FD Application lapsed

Owner name: RHONE-POULENC SANTE