FI860456A - Bis-indolalkaloiders proteinkonjugat, bis-indolalkaloider, deras framstaellning och anvaendning. - Google Patents

Bis-indolalkaloiders proteinkonjugat, bis-indolalkaloider, deras framstaellning och anvaendning. Download PDF

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Publication number
FI860456A
FI860456A FI860456A FI860456A FI860456A FI 860456 A FI860456 A FI 860456A FI 860456 A FI860456 A FI 860456A FI 860456 A FI860456 A FI 860456A FI 860456 A FI860456 A FI 860456A
Authority
FI
Finland
Prior art keywords
bis
proteinkonjugat
indolalkaloiders
indolalkaloider
deras framstaellning
Prior art date
Application number
FI860456A
Other languages
English (en)
Finnish (fi)
Other versions
FI860456A0 (fi
Inventor
Aarre Huhtikangas
Seppo Lapinjoki
Jarmo Niemi
Original Assignee
Huhtamaeki Oy Laeaeketehdas Le
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from FI852785A external-priority patent/FI80703C/fi
Application filed by Huhtamaeki Oy Laeaeketehdas Le filed Critical Huhtamaeki Oy Laeaeketehdas Le
Priority to FI860456A priority Critical patent/FI860456A/fi
Publication of FI860456A0 publication Critical patent/FI860456A0/fi
Priority to PCT/FI1986/000074 priority patent/WO1987000530A1/fr
Priority to AU61355/86A priority patent/AU6135586A/en
Priority to EP86904190A priority patent/EP0264376A1/fr
Publication of FI860456A publication Critical patent/FI860456A/fi
Priority to NO871035A priority patent/NO871035L/no
Priority to DK132787A priority patent/DK132787D0/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D519/00—Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00
    • C07D519/04—Dimeric indole alkaloids, e.g. vincaleucoblastine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/68—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment
    • A61K47/6801—Drug-antibody or immunoglobulin conjugates defined by the pharmacologically or therapeutically active agent
    • A61K47/6803—Drugs conjugated to an antibody or immunoglobulin, e.g. cisplatin-antibody conjugates
    • A61K47/6805—Drugs conjugated to an antibody or immunoglobulin, e.g. cisplatin-antibody conjugates the drug being a vinca alkaloid

Landscapes

  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Immunology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
FI860456A 1985-07-16 1986-01-31 Bis-indolalkaloiders proteinkonjugat, bis-indolalkaloider, deras framstaellning och anvaendning. FI860456A (fi)

Priority Applications (6)

Application Number Priority Date Filing Date Title
FI860456A FI860456A (fi) 1985-07-16 1986-01-31 Bis-indolalkaloiders proteinkonjugat, bis-indolalkaloider, deras framstaellning och anvaendning.
PCT/FI1986/000074 WO1987000530A1 (fr) 1985-07-16 1986-07-04 Conjugues de proteines d'alcaloides de bis-indole, alcaloides de bis-indole, leur preparation et leur application
AU61355/86A AU6135586A (en) 1985-07-16 1986-07-04 Protein conjugates of bis-indole alkaloids, bis-indole alkaloids, their preparation and application
EP86904190A EP0264376A1 (fr) 1985-07-16 1986-07-04 Conjugues de proteines d'alcaloides de bis-indole, alcaloides de bis-indole, leur preparation et leur application
NO871035A NO871035L (no) 1985-07-16 1987-03-13 Konjugerte proteiner av bis-indolalkaloider, bis-indolalkaloider, samt fremgangsmaate til fremstilling og anvendelse derav.
DK132787A DK132787D0 (da) 1985-07-16 1987-03-16 Proteinkonjugater af bis-indol alkaloider, bis-indol alkaloider, deres fremstilling og anvendelse

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FI852785A FI80703C (fi) 1985-07-16 1985-07-16 Bis-indolalkaloiders proteinkonjugat, deras framstaellning och anvaendning.
FI860456A FI860456A (fi) 1985-07-16 1986-01-31 Bis-indolalkaloiders proteinkonjugat, bis-indolalkaloider, deras framstaellning och anvaendning.

Publications (2)

Publication Number Publication Date
FI860456A0 FI860456A0 (fi) 1986-01-31
FI860456A true FI860456A (fi) 1987-01-17

Family

ID=26157788

Family Applications (1)

Application Number Title Priority Date Filing Date
FI860456A FI860456A (fi) 1985-07-16 1986-01-31 Bis-indolalkaloiders proteinkonjugat, bis-indolalkaloider, deras framstaellning och anvaendning.

Country Status (5)

Country Link
EP (1) EP0264376A1 (fr)
AU (1) AU6135586A (fr)
DK (1) DK132787D0 (fr)
FI (1) FI860456A (fr)
WO (1) WO1987000530A1 (fr)

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1364925A (en) * 1970-11-16 1974-08-29 Gross S J Immunochemical assaying for tetrahydrocannabinol and materials therefor
US3809782A (en) * 1972-03-10 1974-05-07 Hoffmann La Roche Tubocurarine antigens and antibodies specific therefor
OA06421A (fr) * 1980-06-10 1981-09-30 Omnium Chimique Sa Procédé de préparation de dérivés N-(vinblastinoyl-23) d'acides aminés et de peptides.
FI820020L (fi) * 1981-01-12 1982-07-13 Lilly Industries Ltd Immunoglobulinkonjugater
DE3482444D1 (de) * 1983-03-30 1990-07-19 Lilly Industries Ltd Immunoglobulinkonjugate.
US4522750A (en) * 1984-02-21 1985-06-11 Eli Lilly And Company Cytotoxic compositions of transferrin coupled to vinca alkaloids

Also Published As

Publication number Publication date
EP0264376A1 (fr) 1988-04-27
DK132787A (da) 1987-03-16
AU6135586A (en) 1987-02-10
WO1987000530A1 (fr) 1987-01-29
FI860456A0 (fi) 1986-01-31
DK132787D0 (da) 1987-03-16

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Legal Events

Date Code Title Description
FD Application lapsed

Owner name: HUHTAMAEKI OY LAEAEKETEHDAS LEIRAS