AU6135586A - Protein conjugates of bis-indole alkaloids, bis-indole alkaloids, their preparation and application - Google Patents

Protein conjugates of bis-indole alkaloids, bis-indole alkaloids, their preparation and application

Info

Publication number
AU6135586A
AU6135586A AU61355/86A AU6135586A AU6135586A AU 6135586 A AU6135586 A AU 6135586A AU 61355/86 A AU61355/86 A AU 61355/86A AU 6135586 A AU6135586 A AU 6135586A AU 6135586 A AU6135586 A AU 6135586A
Authority
AU
Australia
Prior art keywords
bis
indole alkaloids
preparation
application
protein conjugates
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU61355/86A
Inventor
Aarre Huhtikangas
Seppo Lapinjoki
Jarmo Niemi
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Huhtamaki Oyj
Original Assignee
Huhtamaki Oyj
Huhtamaki Yhtyma OY
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from FI852785A external-priority patent/FI80703C/en
Application filed by Huhtamaki Oyj, Huhtamaki Yhtyma OY filed Critical Huhtamaki Oyj
Publication of AU6135586A publication Critical patent/AU6135586A/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D519/00—Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00
    • C07D519/04—Dimeric indole alkaloids, e.g. vincaleucoblastine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/68—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment
    • A61K47/6801—Drug-antibody or immunoglobulin conjugates defined by the pharmacologically or therapeutically active agent
    • A61K47/6803—Drugs conjugated to an antibody or immunoglobulin, e.g. cisplatin-antibody conjugates
    • A61K47/6805—Drugs conjugated to an antibody or immunoglobulin, e.g. cisplatin-antibody conjugates the drug being a vinca alkaloid

Landscapes

  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Immunology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
AU61355/86A 1985-07-16 1986-07-04 Protein conjugates of bis-indole alkaloids, bis-indole alkaloids, their preparation and application Abandoned AU6135586A (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
FI852785A FI80703C (en) 1985-07-16 1985-07-16 BIS-INDOLALKALOIDERS PROTEIN CONJUGAT, DERAS FRAMSTAELLNING OCH ANVAENDNING.
FI852785 1985-07-16
FI860456A FI860456A (en) 1985-07-16 1986-01-31 BIS-INDOLALKALOIDERS PROTEINKONJUGAT, BIS-INDOLALKALOIDER, DERAS FRAMSTAELLNING OCH ANVAENDNING.
FI860456 1986-01-31

Publications (1)

Publication Number Publication Date
AU6135586A true AU6135586A (en) 1987-02-10

Family

ID=26157788

Family Applications (1)

Application Number Title Priority Date Filing Date
AU61355/86A Abandoned AU6135586A (en) 1985-07-16 1986-07-04 Protein conjugates of bis-indole alkaloids, bis-indole alkaloids, their preparation and application

Country Status (5)

Country Link
EP (1) EP0264376A1 (en)
AU (1) AU6135586A (en)
DK (1) DK132787D0 (en)
FI (1) FI860456A (en)
WO (1) WO1987000530A1 (en)

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1364925A (en) * 1970-11-16 1974-08-29 Gross S J Immunochemical assaying for tetrahydrocannabinol and materials therefor
US3809782A (en) * 1972-03-10 1974-05-07 Hoffmann La Roche Tubocurarine antigens and antibodies specific therefor
OA06421A (en) * 1980-06-10 1981-09-30 Omnium Chimique Sa Process for the preparation of N- (vinblastinoyl-23) derivatives of amino acids and peptides.
FI820020L (en) * 1981-01-12 1982-07-13 Lilly Industries Ltd IMMUNOGLOBULINKONJUGATER
DE3482444D1 (en) * 1983-03-30 1990-07-19 Lilly Industries Ltd IMMUNOGLOBULIN CONJUGATES.
US4522750A (en) * 1984-02-21 1985-06-11 Eli Lilly And Company Cytotoxic compositions of transferrin coupled to vinca alkaloids

Also Published As

Publication number Publication date
EP0264376A1 (en) 1988-04-27
DK132787A (en) 1987-03-16
FI860456A (en) 1987-01-17
WO1987000530A1 (en) 1987-01-29
FI860456A0 (en) 1986-01-31
DK132787D0 (en) 1987-03-16

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