FI851073L - INHIBITOR FOER DOPAMIN- HYDROXYLAS. - Google Patents

INHIBITOR FOER DOPAMIN- HYDROXYLAS.

Info

Publication number
FI851073L
FI851073L FI851073A FI851073A FI851073L FI 851073 L FI851073 L FI 851073L FI 851073 A FI851073 A FI 851073A FI 851073 A FI851073 A FI 851073A FI 851073 L FI851073 L FI 851073L
Authority
FI
Finland
Prior art keywords
hydroxylas
dopamin
foer
inhibitor
formula
Prior art date
Application number
FI851073A
Other languages
Finnish (fi)
Other versions
FI83309B (en
FI83309C (en
FI851073A0 (en
Inventor
James Simpson Frazee
Carl Kaiser
Lawrence Ivan Kruse
Original Assignee
Smithkline Beckman Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Smithkline Beckman Corp filed Critical Smithkline Beckman Corp
Publication of FI851073A0 publication Critical patent/FI851073A0/en
Publication of FI851073L publication Critical patent/FI851073L/en
Publication of FI83309B publication Critical patent/FI83309B/en
Application granted granted Critical
Publication of FI83309C publication Critical patent/FI83309C/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/32—One oxygen, sulfur or nitrogen atom
    • C07D239/38—One sulfur atom
    • C07D239/40—One sulfur atom as doubly bound sulfur atom or as unsubstituted mercapto radical

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

The invention relates to a process for the preparation of compounds of the formula I, which inhibit the effect of DBH in mammals. According to the invention compounds of the formula II are reacted with acid thiocyanate. <IMAGE>
FI851073A 1984-03-19 1985-03-18 FOERFARANDE FOER FRAMSTAELLNING AV DOPAMIN- -HYDROXYLAS INHIBERANDE 1-FENYLALKYL-2 -MERKAPTOIMIDAZOLDERIVAT. FI83309C (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US59066584A 1984-03-19 1984-03-19
US59066584 1984-03-19

Publications (4)

Publication Number Publication Date
FI851073A0 FI851073A0 (en) 1985-03-18
FI851073L true FI851073L (en) 1985-09-20
FI83309B FI83309B (en) 1991-03-15
FI83309C FI83309C (en) 1991-06-25

Family

ID=24363168

Family Applications (1)

Application Number Title Priority Date Filing Date
FI851073A FI83309C (en) 1984-03-19 1985-03-18 FOERFARANDE FOER FRAMSTAELLNING AV DOPAMIN- -HYDROXYLAS INHIBERANDE 1-FENYLALKYL-2 -MERKAPTOIMIDAZOLDERIVAT.

Country Status (9)

Country Link
KR (1) KR850006189A (en)
DK (2) DK118985A (en)
FI (1) FI83309C (en)
HU (1) HU194184B (en)
IL (1) IL74586A (en)
NO (1) NO162616C (en)
NZ (2) NZ222876A (en)
PH (1) PH21032A (en)
ZW (1) ZW4285A1 (en)

Also Published As

Publication number Publication date
HU194184B (en) 1988-01-28
FI83309B (en) 1991-03-15
NO851056L (en) 1985-09-20
KR850006189A (en) 1985-10-02
NO162616B (en) 1989-10-16
IL74586A (en) 1988-11-30
NZ211440A (en) 1988-09-29
DK189691A (en) 1991-11-20
DK118985D0 (en) 1985-03-15
HUT37602A (en) 1986-01-23
FI83309C (en) 1991-06-25
PH21032A (en) 1987-06-30
DK189691D0 (en) 1991-11-20
FI851073A0 (en) 1985-03-18
NO162616C (en) 1990-01-24
NZ222876A (en) 1988-09-29
DK118985A (en) 1985-09-20
IL74586A0 (en) 1985-06-30
ZW4285A1 (en) 1985-06-26

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Legal Events

Date Code Title Description
MM Patent lapsed

Owner name: SMITHKLINE BECKMAN CORPORATION