FI842795A - Foerfarande foer framstaellning av pyrrolidinoner med inverkan pao nervsystemet. - Google Patents

Foerfarande foer framstaellning av pyrrolidinoner med inverkan pao nervsystemet. Download PDF

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Publication number
FI842795A
FI842795A FI842795A FI842795A FI842795A FI 842795 A FI842795 A FI 842795A FI 842795 A FI842795 A FI 842795A FI 842795 A FI842795 A FI 842795A FI 842795 A FI842795 A FI 842795A
Authority
FI
Finland
Prior art keywords
pyrrolidinoner
nervsystemet
inverkan
pao
med
Prior art date
Application number
FI842795A
Other languages
English (en)
Other versions
FI77848C (fi
FI77848B (fi
FI842795A0 (fi
Inventor
Kathleen Biziere
Jean-Pierre Chambon
Jean-Charles Molimard
Original Assignee
Sanofi Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanofi Sa filed Critical Sanofi Sa
Publication of FI842795A0 publication Critical patent/FI842795A0/fi
Publication of FI842795A publication Critical patent/FI842795A/fi
Application granted granted Critical
Publication of FI77848B publication Critical patent/FI77848B/fi
Publication of FI77848C publication Critical patent/FI77848C/fi

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D207/00Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/18Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D207/22Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/24Oxygen or sulfur atoms
    • C07D207/262-Pyrrolidones
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/08Antiepileptics; Anticonvulsants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/20Hypnotics; Sedatives
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C205/00Compounds containing nitro groups bound to a carbon skeleton
    • C07C205/49Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by carboxyl groups
    • C07C205/50Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by carboxyl groups having nitro groups and carboxyl groups bound to acyclic carbon atoms of the carbon skeleton
    • C07C205/51Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by carboxyl groups having nitro groups and carboxyl groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being saturated
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D407/00Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
    • C07D407/02Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings
    • C07D407/06Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D409/00Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/06Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F7/00Compounds containing elements of Groups 4 or 14 of the Periodic Table
    • C07F7/02Silicon compounds
    • C07F7/08Compounds having one or more C—Si linkages
    • C07F7/10Compounds having one or more C—Si linkages containing nitrogen having a Si-N linkage
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02Phosphorus compounds
    • C07F9/547Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/6527Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07F9/6533Six-membered rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Neurosurgery (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Neurology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Molecular Biology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Biochemistry (AREA)
  • Pain & Pain Management (AREA)
  • Anesthesiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyrrole Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
FI842795A 1983-07-12 1984-07-11 Foerfarande foer framstaellning av terapeutiskt aktiva pyrrolidinoner. FI77848C (fi)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR8311636A FR2549053B1 (fr) 1983-07-12 1983-07-12 Nouveaux derives de la pyrrolidine actifs sur le systeme nerveux central, leur procede de preparation, les medicaments en contenant
FR8311636 1983-07-12

Publications (4)

Publication Number Publication Date
FI842795A0 FI842795A0 (fi) 1984-07-11
FI842795A true FI842795A (fi) 1985-01-13
FI77848B FI77848B (fi) 1989-01-31
FI77848C FI77848C (fi) 1989-05-10

Family

ID=9290775

Family Applications (1)

Application Number Title Priority Date Filing Date
FI842795A FI77848C (fi) 1983-07-12 1984-07-11 Foerfarande foer framstaellning av terapeutiskt aktiva pyrrolidinoner.

Country Status (23)

Country Link
US (1) US4604383A (fi)
EP (1) EP0135406B1 (fi)
JP (1) JPS6084265A (fi)
KR (1) KR910003362B1 (fi)
AR (1) AR240451A1 (fi)
AT (1) ATE30150T1 (fi)
AU (1) AU560725B2 (fi)
CA (1) CA1249593A (fi)
DD (2) DD227962A5 (fi)
DE (1) DE3466686D1 (fi)
DK (1) DK343784A (fi)
ES (1) ES8504122A1 (fi)
FI (1) FI77848C (fi)
FR (1) FR2549053B1 (fi)
GR (1) GR81502B (fi)
HU (1) HU192564B (fi)
IL (1) IL72324A (fi)
NO (1) NO163617C (fi)
NZ (1) NZ208865A (fi)
PT (1) PT78874B (fi)
SU (1) SU1391497A3 (fi)
YU (2) YU121384A (fi)
ZA (1) ZA845397B (fi)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3336024A1 (de) * 1983-10-04 1985-04-18 Boehringer Ingelheim KG, 6507 Ingelheim 4-amino-l-benzyl-pyrrolidinone und ihre saeureadditionssalze, verfahren zu ihrer herstellung und arzneimittel
EP0342613B1 (en) * 1988-05-20 1992-11-11 ZAMBON GROUP S.p.A. Compounds with central analgesic activity, process for their preparation and pharmaceutical compositions containing them
GB9307431D0 (en) * 1993-04-08 1993-06-02 Oxford Asymmetry Ltd Improvements in or relating to chiral auxiliaries
CN106977415B (zh) * 2016-01-15 2021-03-26 广东东阳光药业有限公司 一种沙库必曲的中间体及其制备方法
WO2017148357A1 (zh) * 2016-02-29 2017-09-08 广东东阳光药业有限公司 一种沙库必曲的中间体及其制备方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3272842A (en) * 1965-06-25 1966-09-13 Lilly Co Eli Novel pyrrolinones
AU518986B2 (en) * 1977-10-11 1981-10-29 Takeda Chemical Industries Ltd. Lactams
FR2436779A1 (fr) * 1978-09-22 1980-04-18 Pharmindustrie Derives de pyrrolidine-2 methanol utilisables comme medicaments

Also Published As

Publication number Publication date
EP0135406A1 (fr) 1985-03-27
US4604383A (en) 1986-08-05
FI77848C (fi) 1989-05-10
GR81502B (fi) 1984-12-11
NO163617C (no) 1990-06-27
DK343784D0 (da) 1984-07-12
FR2549053B1 (fr) 1985-12-27
NO163617B (no) 1990-03-19
DE3466686D1 (en) 1987-11-12
YU81086A (en) 1986-10-31
FI77848B (fi) 1989-01-31
ES534221A0 (es) 1985-04-16
AR240451A1 (es) 1990-04-30
HUT34443A (en) 1985-03-28
ES8504122A1 (es) 1985-04-16
JPS6084265A (ja) 1985-05-13
SU1391497A3 (ru) 1988-04-23
PT78874A (fr) 1984-08-01
CA1249593A (en) 1989-01-31
NZ208865A (en) 1986-12-05
DD227962A5 (de) 1985-10-02
EP0135406B1 (fr) 1987-10-07
FR2549053A1 (fr) 1985-01-18
PT78874B (fr) 1986-06-02
IL72324A (en) 1987-10-30
NO842821L (no) 1985-01-14
DK343784A (da) 1985-01-13
DD229121A5 (de) 1985-10-30
IL72324A0 (en) 1984-11-30
AU3021684A (en) 1985-01-17
YU121384A (en) 1986-10-31
AU560725B2 (en) 1987-04-16
KR850001165A (ko) 1985-03-16
HU192564B (en) 1987-06-29
KR910003362B1 (ko) 1991-05-28
ATE30150T1 (de) 1987-10-15
FI842795A0 (fi) 1984-07-11
ZA845397B (en) 1985-02-27

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Owner name: SANOFI