FI834215A7 - Sydänlääkkeenä käyttökelpoisia 2(1H)- pyridinoneja sekä niiden valmistus. - Google Patents

Sydänlääkkeenä käyttökelpoisia 2(1H)- pyridinoneja sekä niiden valmistus. Download PDF

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Publication number
FI834215A7
FI834215A7 FI834215A FI834215A FI834215A7 FI 834215 A7 FI834215 A7 FI 834215A7 FI 834215 A FI834215 A FI 834215A FI 834215 A FI834215 A FI 834215A FI 834215 A7 FI834215 A7 FI 834215A7
Authority
FI
Finland
Prior art keywords
preparation
cardiac drugs
pyridinones
useful
pyridinones useful
Prior art date
Application number
FI834215A
Other languages
English (en)
Finnish (fi)
Swedish (sv)
Other versions
FI834215L (fi
FI834215A0 (fi
Inventor
George Yohe Lesher
Baldev Singh
Philip Michael Carabateas
Original Assignee
Sterling Drug Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US06/442,623 external-priority patent/US4431651A/en
Application filed by Sterling Drug Inc filed Critical Sterling Drug Inc
Publication of FI834215A0 publication Critical patent/FI834215A0/fi
Publication of FI834215L publication Critical patent/FI834215L/fi
Publication of FI834215A7 publication Critical patent/FI834215A7/fi

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/62—Oxygen or sulfur atoms
    • C07D213/63—One oxygen atom
    • C07D213/64—One oxygen atom attached in position 2 or 6
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/80—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D211/84—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen directly attached to ring carbon atoms
    • C07D211/86—Oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/54—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/55—Acids; Esters
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/54—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/57—Nitriles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pyridine Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
FI834215A 1982-11-18 1983-11-17 Sydänlääkkeenä käyttökelpoisia 2(1H)- pyridinoneja sekä niiden valmistus. FI834215A7 (fi)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US06/442,623 US4431651A (en) 1982-11-18 1982-11-18 2-Pyridinones and their use as cardiotonic agents
US44324982A 1982-11-22 1982-11-22

Publications (3)

Publication Number Publication Date
FI834215A0 FI834215A0 (fi) 1983-11-17
FI834215L FI834215L (fi) 1984-05-19
FI834215A7 true FI834215A7 (fi) 1984-05-19

Family

ID=27033231

Family Applications (1)

Application Number Title Priority Date Filing Date
FI834215A FI834215A7 (fi) 1982-11-18 1983-11-17 Sydänlääkkeenä käyttökelpoisia 2(1H)- pyridinoneja sekä niiden valmistus.

Country Status (11)

Country Link
EP (1) EP0109628A1 (enExample)
KR (1) KR840006625A (enExample)
AU (1) AU2141383A (enExample)
DK (1) DK527383A (enExample)
ES (1) ES527344A0 (enExample)
FI (1) FI834215A7 (enExample)
GR (1) GR79123B (enExample)
IL (1) IL70169A0 (enExample)
NO (1) NO834227L (enExample)
NZ (1) NZ206215A (enExample)
PT (1) PT77670B (enExample)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3427146A1 (de) * 1984-07-24 1986-02-06 Dynamit Nobel Ag, 5210 Troisdorf Neue pyridon-derivate
DE3433953A1 (de) * 1984-09-15 1986-03-27 A. Nattermann & Cie GmbH, 5000 Köln Neue, eine imidazol-gruppe enthaltende 3,4-dihydro-2(1h)-pyridone und2(1h)-pyridone, verfahren zu ihrer herstellung und diese enthaltende arzneimittel
PE20060285A1 (es) 2004-03-30 2006-05-08 Aventis Pharma Inc Piridonas sustituidas como inhibidores de pol(adp-ribosa)-polimerasa (parp)
DE102004050196A1 (de) * 2004-10-15 2006-04-20 Sanofi-Aventis Deutschland Gmbh Substituierte 2-Pyridon-Derivate, Verfahren zu ihrer Herstellung und ihre Verwendung als Medikament
WO2008133660A2 (en) 2006-11-21 2008-11-06 Qd Vision, Inc. Nanocrystals including a group iiia element and a group va element, method, composition, device and other prodcucts
WO2013028253A1 (en) 2011-08-19 2013-02-28 Qd Vision, Inc. Semiconductor nanocrystals and methods
WO2013173409A1 (en) 2012-05-15 2013-11-21 Qd Vision, Inc. Semiconductor nanocrystals and methods of preparation

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3718743A (en) * 1970-11-19 1973-02-27 Merck & Co Inc 5-phenyl-2-piperidones and 5-phenyl-2-thiopiperidones in compositions and methods for treating pain, fever and inflammation
IL61501A (en) * 1979-11-26 1984-06-29 Sterling Drug Inc 5-(pyridinyl)-2(1h)-pyridinones,their preparation and pharmaceutical compositions containing them
FI820573L (fi) * 1981-03-03 1982-09-04 Lilly Co Eli 1-bentsoyl-3-(arylpyridyl)ureafoereningar beroerande eller till dessa hoerande foerbaettringar
US4465686A (en) * 1981-09-08 1984-08-14 Sterling Drug Inc. 5-(Hydroxy- and/or amino-phenyl)-6-(lower-alkyl)-2-(1H)-pyridinones, their cardiotonic use and preparation

Also Published As

Publication number Publication date
ES8601138A1 (es) 1985-10-01
GR79123B (enExample) 1984-10-02
PT77670A (en) 1983-12-01
DK527383A (da) 1984-05-19
NO834227L (no) 1984-05-21
KR840006625A (ko) 1984-12-01
FI834215L (fi) 1984-05-19
EP0109628A1 (en) 1984-05-30
NZ206215A (en) 1986-01-24
DK527383D0 (da) 1983-11-17
IL70169A0 (en) 1984-02-29
FI834215A0 (fi) 1983-11-17
PT77670B (en) 1986-03-27
ES527344A0 (es) 1985-10-01
AU2141383A (en) 1984-05-24

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Legal Events

Date Code Title Description
FA Application withdrawn [patent]

Owner name: STERLING DRUG INC