FI831998A7 - Menetelmä farmaseuttisesti aktiivisten pyratsinonijohdannaisten valmistamiseksi. - Google Patents
Menetelmä farmaseuttisesti aktiivisten pyratsinonijohdannaisten valmistamiseksi. Download PDFInfo
- Publication number
- FI831998A7 FI831998A7 FI831998A FI831998A FI831998A7 FI 831998 A7 FI831998 A7 FI 831998A7 FI 831998 A FI831998 A FI 831998A FI 831998 A FI831998 A FI 831998A FI 831998 A7 FI831998 A7 FI 831998A7
- Authority
- FI
- Finland
- Prior art keywords
- preparation
- pharmaceutically active
- pyrazinone derivatives
- pyrazinone
- derivatives
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
- C07D241/02—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings
- C07D241/10—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
- C07D241/14—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D241/18—Oxygen or sulfur atoms
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB8216437 | 1982-06-05 | ||
| GB838300476A GB8300476D0 (en) | 1983-01-08 | 1983-01-08 | Heterocyclic compounds |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| FI831998A0 FI831998A0 (fi) | 1983-06-03 |
| FI831998L FI831998L (fi) | 1983-12-06 |
| FI831998A7 true FI831998A7 (fi) | 1983-12-06 |
Family
ID=26283037
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FI831998A FI831998A7 (fi) | 1982-06-05 | 1983-06-03 | Menetelmä farmaseuttisesti aktiivisten pyratsinonijohdannaisten valmistamiseksi. |
Country Status (15)
| Country | Link |
|---|---|
| US (2) | US4514568A (online.php) |
| EP (1) | EP0096517A3 (online.php) |
| KR (1) | KR840005111A (online.php) |
| AU (1) | AU1527583A (online.php) |
| DD (1) | DD209818A5 (online.php) |
| DK (1) | DK247783A (online.php) |
| ES (2) | ES8500244A1 (online.php) |
| FI (1) | FI831998A7 (online.php) |
| GR (1) | GR79299B (online.php) |
| JO (1) | JO1255B1 (online.php) |
| NO (1) | NO832016L (online.php) |
| PL (1) | PL242354A1 (online.php) |
| PT (1) | PT76791B (online.php) |
| RO (1) | RO86851B (online.php) |
| ZW (1) | ZW12783A1 (online.php) |
Families Citing this family (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4657906A (en) * | 1982-06-05 | 1987-04-14 | Smith Kline & French Laboratories Ltd. | Heterocyclic compounds having inotropic activity |
| GB8332313D0 (en) * | 1983-12-02 | 1984-01-11 | Smith Kline French Lab | Chemical compounds |
| US4595766A (en) * | 1984-10-26 | 1986-06-17 | Ciba-Geigy Corporation | Process for the preparation of an indoline carboxylic acid |
| US4697016A (en) * | 1984-10-26 | 1987-09-29 | Ciba-Geigy Corporation | Intermediates for the preparation of a carboxylic acid |
| JPS62198671A (ja) * | 1986-02-25 | 1987-09-02 | Toyo Jozo Co Ltd | １−置換アルキル１，２−ジヒドロ−２−ピラジノン誘導体 |
| US7772188B2 (en) | 2003-01-28 | 2010-08-10 | Ironwood Pharmaceuticals, Inc. | Methods and compositions for the treatment of gastrointestinal disorders |
| US8969514B2 (en) | 2007-06-04 | 2015-03-03 | Synergy Pharmaceuticals, Inc. | Agonists of guanylate cyclase useful for the treatment of hypercholesterolemia, atherosclerosis, coronary heart disease, gallstone, obesity and other cardiovascular diseases |
| CA2688161C (en) | 2007-06-04 | 2020-10-20 | Kunwar Shailubhai | Agonists of guanylate cyclase useful for the treatment of gastrointestinal disorders, inflammation, cancer and other disorders |
| EP2328910B1 (en) | 2008-06-04 | 2014-08-06 | Synergy Pharmaceuticals Inc. | Agonists of guanylate cyclase useful for the treatment of gastrointestinal disorders, inflammation, cancer and other disorders |
| EP3241839B1 (en) | 2008-07-16 | 2019-09-04 | Bausch Health Ireland Limited | Agonists of guanylate cyclase useful for the treatment of gastrointestinal, inflammation, cancer and other disorders |
| EP2467137A1 (en) * | 2009-08-19 | 2012-06-27 | Ambit Biosciences Corporation | Biaryl compounds and methods of use thereof |
| US9616097B2 (en) | 2010-09-15 | 2017-04-11 | Synergy Pharmaceuticals, Inc. | Formulations of guanylate cyclase C agonists and methods of use |
| DK2681236T3 (en) | 2011-03-01 | 2018-04-16 | Synergy Pharmaceuticals Inc | PROCEDURE FOR MANUFACTURING GUANYLATE CYCLASE-C-AGONISTS |
| SG11201408324QA (en) * | 2012-06-12 | 2015-01-29 | Abbvie Inc | Pyridinone and pyridazinone derivatives |
| CA2902348C (en) | 2013-02-25 | 2021-11-30 | Synergy Pharmaceuticals Inc. | Agonists of guanylate cyclase and their uses |
| HK1220611A1 (zh) | 2013-03-15 | 2017-05-12 | Bausch Health Ireland Limited | 用於治疗胃肠道病症的组成物 |
| WO2014151206A1 (en) | 2013-03-15 | 2014-09-25 | Synergy Pharmaceuticals Inc. | Agonists of guanylate cyclase and their uses |
| CN113388007A (zh) | 2013-06-05 | 2021-09-14 | 博士医疗爱尔兰有限公司 | 鸟苷酸环化酶c的超纯激动剂、制备和使用所述激动剂的方法 |
| BR112016002789A2 (pt) | 2013-08-09 | 2017-11-21 | Ardelyx Inc | compostos e métodos para inibir transporte de fosfato |
| WO2020237096A1 (en) | 2019-05-21 | 2020-11-26 | Ardelyx, Inc. | Combination for lowering serum phosphate in a patient |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3745161A (en) * | 1970-04-20 | 1973-07-10 | Merck & Co Inc | Phenyl-hydroxy-pyrazine carboxylic acids and derivatives |
-
1983
- 1983-05-27 EP EP83303059A patent/EP0096517A3/en not_active Withdrawn
- 1983-06-01 PT PT76791A patent/PT76791B/pt unknown
- 1983-06-01 GR GR71530A patent/GR79299B/el unknown
- 1983-06-01 JO JO19831255A patent/JO1255B1/en active
- 1983-06-01 AU AU15275/83A patent/AU1527583A/en not_active Abandoned
- 1983-06-01 DK DK247783A patent/DK247783A/da not_active Application Discontinuation
- 1983-06-02 US US06/500,484 patent/US4514568A/en not_active Expired - Fee Related
- 1983-06-02 US US06/500,486 patent/US4556711A/en not_active Expired - Lifetime
- 1983-06-03 DD DD25173683A patent/DD209818A5/de unknown
- 1983-06-03 RO RO111170A patent/RO86851B/ro unknown
- 1983-06-03 NO NO832016A patent/NO832016L/no unknown
- 1983-06-03 ES ES522962A patent/ES8500244A1/es not_active Expired
- 1983-06-03 ZW ZW127/83A patent/ZW12783A1/xx unknown
- 1983-06-03 PL PL24235483A patent/PL242354A1/xx unknown
- 1983-06-03 FI FI831998A patent/FI831998A7/fi not_active Application Discontinuation
- 1983-06-04 KR KR1019830002511A patent/KR840005111A/ko not_active Withdrawn
-
1984
- 1984-02-24 ES ES530024A patent/ES530024A0/es active Granted
Also Published As
| Publication number | Publication date |
|---|---|
| FI831998A0 (fi) | 1983-06-03 |
| RO86851A (ro) | 1985-05-20 |
| DD209818A5 (de) | 1984-05-23 |
| RO86851B (ro) | 1985-05-31 |
| EP0096517A2 (en) | 1983-12-21 |
| ES8707507A1 (es) | 1985-12-01 |
| US4556711A (en) | 1985-12-03 |
| ES522962A0 (es) | 1984-10-01 |
| JO1255B1 (en) | 1985-04-20 |
| EP0096517A3 (en) | 1985-04-03 |
| PT76791A (en) | 1983-07-01 |
| ZW12783A1 (en) | 1983-08-24 |
| ES8500244A1 (es) | 1984-10-01 |
| NO832016L (no) | 1983-12-06 |
| DK247783A (da) | 1983-12-06 |
| GR79299B (online.php) | 1984-10-22 |
| PL242354A1 (en) | 1984-12-17 |
| AU1527583A (en) | 1983-12-08 |
| FI831998L (fi) | 1983-12-06 |
| ES530024A0 (es) | 1985-12-01 |
| PT76791B (en) | 1986-01-24 |
| KR840005111A (ko) | 1984-11-03 |
| DK247783D0 (da) | 1983-06-01 |
| US4514568A (en) | 1985-04-30 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FA | Application withdrawn [patent] |
Owner name: SMITH KLINE & FRENCH LABORATORIES |