FI830299A0 - Difosfonsyra-derivat och dessa innehaollande farmaceutiska produkter - Google Patents

Difosfonsyra-derivat och dessa innehaollande farmaceutiska produkter

Info

Publication number
FI830299A0
FI830299A0 FI830299A FI830299A FI830299A0 FI 830299 A0 FI830299 A0 FI 830299A0 FI 830299 A FI830299 A FI 830299A FI 830299 A FI830299 A FI 830299A FI 830299 A0 FI830299 A0 FI 830299A0
Authority
FI
Finland
Prior art keywords
diphosphonyra
derivatives
pharmaceutical product
chemicals
chemicals pharmaceutical
Prior art date
Application number
FI830299A
Other languages
English (en)
Other versions
FI77041C (fi
FI77041B (fi
FI830299L (fi
Inventor
Helmut Biere
Clemens Rufer
Irmgard Boettcher
Original Assignee
Schering Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE19823203309 external-priority patent/DE3203309A1/de
Priority claimed from DE19823225468 external-priority patent/DE3225468A1/de
Application filed by Schering Ag filed Critical Schering Ag
Publication of FI830299A0 publication Critical patent/FI830299A0/fi
Publication of FI830299L publication Critical patent/FI830299L/fi
Application granted granted Critical
Publication of FI77041B publication Critical patent/FI77041B/fi
Publication of FI77041C publication Critical patent/FI77041C/fi

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/28—Phosphorus compounds with one or more P—C bonds
    • C07F9/38—Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)]
    • C07F9/40—Esters thereof
    • C07F9/4003—Esters thereof the acid moiety containing a substituent or a structure which is considered as characteristic
    • C07F9/4025—Esters of poly(thio)phosphonic acids
    • C07F9/404—Esters of poly(thio)phosphonic acids containing hydroxy substituents in the hydrocarbon radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/28—Phosphorus compounds with one or more P—C bonds
    • C07F9/38—Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)]
    • C07F9/3804—Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)] not used, see subgroups
    • C07F9/3839—Polyphosphonic acids
    • C07F9/386—Polyphosphonic acids containing hydroxy substituents in the hydrocarbon radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/6553—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having sulfur atoms, with or without selenium or tellurium atoms, as the only ring hetero atoms
    • C07F9/655345—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having sulfur atoms, with or without selenium or tellurium atoms, as the only ring hetero atoms the sulfur atom being part of a five-membered ring

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
FI830299A 1982-01-27 1983-01-27 Foerfarande foer framstaellning av nya, terapeutiskt anvaendbara difosfonsyraderivat. FI77041C (fi)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
DE19823203309 DE3203309A1 (de) 1982-01-27 1982-01-27 Diphosphonsaeure-derivate und diese enthaltende pharmazeutische praeparate
DE3203309 1982-01-27
DE19823225468 DE3225468A1 (de) 1982-07-05 1982-07-05 Diphosphonsaeure-derivate und diese enthaltende pharmazeutische praeparate
DE3225468 1982-07-05

Publications (4)

Publication Number Publication Date
FI830299A0 true FI830299A0 (fi) 1983-01-27
FI830299L FI830299L (fi) 1983-07-28
FI77041B FI77041B (fi) 1988-09-30
FI77041C FI77041C (fi) 1989-01-10

Family

ID=25799266

Family Applications (1)

Application Number Title Priority Date Filing Date
FI830299A FI77041C (fi) 1982-01-27 1983-01-27 Foerfarande foer framstaellning av nya, terapeutiskt anvaendbara difosfonsyraderivat.

Country Status (10)

Country Link
US (1) US4473560A (fi)
EP (1) EP0085321B1 (fi)
AU (1) AU559513B2 (fi)
CA (1) CA1202635A (fi)
DE (1) DE3365492D1 (fi)
DK (1) DK30083A (fi)
ES (1) ES8400118A1 (fi)
FI (1) FI77041C (fi)
GR (1) GR77145B (fi)
IL (1) IL67763A0 (fi)

Families Citing this family (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3364638A (en) * 1965-08-02 1968-01-23 Johnson & Johnson Composite plastic and corrugated panel
FR2531088B1 (fr) * 1982-07-29 1987-08-28 Sanofi Sa Produits anti-inflammatoires derives de l'acide methylenediphosphonique et leur procede de preparation
DE3334211A1 (de) * 1983-09-22 1985-04-04 Henkel KGaA, 4000 Düsseldorf Dihydroxyalkandiphosphonsaeuren
DE3428524A1 (de) * 1984-08-02 1986-02-13 Boehringer Mannheim Gmbh, 6800 Mannheim Neue diphosphonsaeurederivate, verfahren zu deren herstellung und diese verbindungen enthaltende arzneimittel
IL77243A (en) * 1984-12-21 1996-11-14 Procter & Gamble Pharmaceutical compositions containing geminal diphosphonic acid compounds and certain such novel compounds
US4902679A (en) * 1985-12-13 1990-02-20 Norwich Eaton Pharmaceuticals, Inc. Methods of treating diseases with certain geminal diphosphonates
DE3623397A1 (de) * 1986-07-11 1988-01-14 Boehringer Mannheim Gmbh Neue diphosphonsaeurederivate, verfahren zu deren herstellung und diese verbindungen enthaltende arzneimittel
DE3822650A1 (de) * 1988-07-05 1990-02-01 Boehringer Mannheim Gmbh Neue diphosphonsaeurederivate, verfahren zu deren herstellung und diese verbindungen enthaltende arzneimittel
JPH0377894A (ja) * 1989-08-18 1991-04-03 Toray Ind Inc メチレンジホスホン酸化合物
US5227506A (en) * 1989-09-06 1993-07-13 Merck & Co., Inc. Acyloxymethyl esters of bisphosphonic acids as bone resorption inhibitors
US5204334A (en) * 1990-10-18 1993-04-20 Ciba-Geigy Corporation Benzoheterocyclylalkylaminoalkanediphosphonic acids, compositions thereof, and use thereof in the treatment of calcium metabolism disorders
AU9097791A (en) * 1990-12-07 1992-07-08 Upjohn Company, The Phosphonic acid derivatives useful as antiinflammatory agents
US5217994A (en) * 1991-08-09 1993-06-08 Merck & Co., Inc. Method of inhibiting osteoclast-mediated bone resorption by administration of aminoalkyl-substituted phenyl derivatives
US5204350A (en) * 1991-08-09 1993-04-20 Merck & Co., Inc. Method of inhibiting osteoclast-mediated bone resorption by administration of n-heterocyclicalkyl-substituted phenyl derivatives
ATE165603T1 (de) * 1991-09-05 1998-05-15 Toray Industries Methandiphosphonsäurederivat, herstellung davon und verwendung davon als arzneimittel
FR2683528A1 (fr) * 1991-11-12 1993-05-14 Bretagne Occidentale Universit Prodrogues et analogues gem-bisphosphoniques d'antiinflammatoires non-sterouidiens de type arylacetique ou arylpropionique.
ES2155446T3 (es) * 1992-07-10 2001-05-16 Toray Industries Derivado de metanodifosfonato, su produccion y su uso farmaceutico.
TW393488B (en) * 1995-04-20 2000-06-11 Merck & Co Inc Process for making 1-hydrox-ybisphosphonates
FR2784031B1 (fr) * 1998-10-02 2002-02-01 Sanofi Elf Utilisation de derives de l'acide bisphosphonique pour la preparation d'un medicament destine au traitement des boiteries
AU2583901A (en) * 1999-12-17 2001-06-25 Ariad Pharmaceuticals, Inc. Proton pump inhibitors
US7115589B2 (en) 1999-12-17 2006-10-03 Ariad Pharmaceuticals, Inc. Purine derivatives
EP1246829A1 (en) * 1999-12-17 2002-10-09 Ariad Pharmaceuticals, Inc. Novel heterocycles
US20030036537A1 (en) * 2001-07-16 2003-02-20 Marc Lecouvey Bisphosphonate derivatives, their preparations and uses
CA2451881A1 (fr) 2001-07-16 2003-01-30 Universite Paris 13 Nouveaux derives de bisphosphonates, leurs preparations et utilisations
FR2827289B1 (fr) * 2001-07-16 2004-07-23 Univ Paris 13 Nouveau derive d'acide diphosphonique, son application en therapeutique et procede de preparation
TW200413381A (en) 2002-11-04 2004-08-01 Hoffmann La Roche Novel amino-substituted dihydropyrimido [4,5-d]pyrimidinone derivatives, their manufacture and use as pharmaceutical agents
US20050065171A1 (en) * 2003-06-25 2005-03-24 Shakespeare William C. Substituted purine derivatives
AU2007226964B2 (en) * 2006-03-17 2012-03-22 The Board Of Trustees Of The University Of Illinois Bisphosphonate compounds and methods

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3664975A (en) * 1970-04-13 1972-05-23 Monsanto Co Flame resistant polyurethane prepared by adding an ethane diphosphonate into the urethane-forming mixture
US4069246A (en) * 1971-12-31 1978-01-17 Henkel Kommanditgesellschaft Auf Aktien Production of 1-hydroxy-alkane-1,1-diphosphonic acids
GB2043072B (en) * 1979-02-13 1983-11-23 Symphar Sa Diphosphonate compounds
EP0084822B1 (de) * 1982-01-27 1986-01-08 Schering Aktiengesellschaft Diphosphonsäure-Derivate und diese enthaltende pharmazeutische Präparate

Also Published As

Publication number Publication date
FI77041C (fi) 1989-01-10
EP0085321A3 (en) 1983-08-17
EP0085321B1 (de) 1986-08-27
AU559513B2 (en) 1987-03-12
DE3365492D1 (en) 1986-10-02
AU1074383A (en) 1983-08-04
CA1202635A (en) 1986-04-01
IL67763A0 (en) 1983-05-15
EP0085321A2 (de) 1983-08-10
GR77145B (fi) 1984-09-07
FI77041B (fi) 1988-09-30
ES519322A0 (es) 1983-11-01
DK30083A (da) 1983-07-28
FI830299L (fi) 1983-07-28
US4473560A (en) 1984-09-25
DK30083D0 (da) 1983-01-26
ES8400118A1 (es) 1983-11-01

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Legal Events

Date Code Title Description
MM Patent lapsed

Owner name: SCHERING AKTIENGESELLSCHAFT