FI820795L - Guanidinderivat - Google Patents

Guanidinderivat

Info

Publication number
FI820795L
FI820795L FI820795A FI820795A FI820795L FI 820795 L FI820795 L FI 820795L FI 820795 A FI820795 A FI 820795A FI 820795 A FI820795 A FI 820795A FI 820795 L FI820795 L FI 820795L
Authority
FI
Finland
Prior art keywords
guanidinderivat
Prior art date
Application number
FI820795A
Other languages
English (en)
Inventor
Tobias Oregon Yellin
David John Gilman
Original Assignee
Ici Plc
Ici America Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ici Plc, Ici America Inc filed Critical Ici Plc
Publication of FI820795L publication Critical patent/FI820795L/fi

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/72Nitrogen atoms
    • C07D213/76Nitrogen atoms to which a second hetero atom is attached
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D231/00Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/14Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D231/38Nitrogen atoms
    • C07D231/40Acylated on said nitrogen atom
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D239/00Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/32One oxygen, sulfur or nitrogen atom
    • C07D239/42One nitrogen atom
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D239/00Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/47One nitrogen atom and one oxygen or sulfur atom, e.g. cytosine
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D241/00Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
    • C07D241/02Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings
    • C07D241/10Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
    • C07D241/14Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D241/20Nitrogen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D249/00Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/041,2,3-Triazoles; Hydrogenated 1,2,3-triazoles
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D249/00Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/041,2,3-Triazoles; Hydrogenated 1,2,3-triazoles
    • C07D249/061,2,3-Triazoles; Hydrogenated 1,2,3-triazoles with aryl radicals directly attached to ring atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D249/00Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/081,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
    • C07D249/101,2,4-Triazoles; Hydrogenated 1,2,4-triazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D249/14Nitrogen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D251/00Heterocyclic compounds containing 1,3,5-triazine rings
    • C07D251/02Heterocyclic compounds containing 1,3,5-triazine rings not condensed with other rings
    • C07D251/12Heterocyclic compounds containing 1,3,5-triazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
    • C07D251/14Heterocyclic compounds containing 1,3,5-triazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hydrogen or carbon atoms directly attached to at least one ring carbon atom
    • C07D251/16Heterocyclic compounds containing 1,3,5-triazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hydrogen or carbon atoms directly attached to at least one ring carbon atom to only one ring carbon atom
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D277/00Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/32Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D277/38Nitrogen atoms
    • C07D277/44Acylated amino or imino radicals
    • C07D277/48Acylated amino or imino radicals by radicals derived from carbonic acid, or sulfur or nitrogen analogues thereof, e.g. carbonylguanidines

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
FI820795A 1981-03-09 1982-03-08 Guanidinderivat FI820795L (fi)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB8107273 1981-03-09
GB8128179 1981-09-17

Publications (1)

Publication Number Publication Date
FI820795L true FI820795L (fi) 1982-09-10

Family

ID=26278698

Family Applications (1)

Application Number Title Priority Date Filing Date
FI820795A FI820795L (fi) 1981-03-09 1982-03-08 Guanidinderivat

Country Status (19)

Country Link
US (2) US4447441A (fi)
EP (1) EP0060094B1 (fi)
AU (3) AU560043B2 (fi)
CA (1) CA1233818A (fi)
DD (1) DD202551A5 (fi)
DE (1) DE3268615D1 (fi)
DK (1) DK101882A (fi)
ES (5) ES8305707A1 (fi)
FI (1) FI820795L (fi)
GR (1) GR74750B (fi)
IE (1) IE52719B1 (fi)
IL (1) IL65216A (fi)
IN (1) IN160139B (fi)
NO (1) NO820726L (fi)
NZ (1) NZ199941A (fi)
PL (1) PL138527B1 (fi)
PT (1) PT74548B (fi)
YU (1) YU49482A (fi)
ZW (1) ZW4182A1 (fi)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1233818A (en) * 1981-03-09 1988-03-08 David J. Gilman Guanidine derivatives as histamine h-2 receptor antagonists
EP0103390A3 (en) * 1982-08-13 1986-02-26 Imperial Chemical Industries Plc Guanidine-containing esters as histamine h2 receptor blockers
GB8320820D0 (en) * 1982-09-03 1983-09-01 Ici Plc Polymorphs
GB8316779D0 (en) * 1982-09-07 1983-07-27 Ici Plc Process
DE3334455A1 (de) * 1983-03-04 1984-09-06 Bayer Ag, 5090 Leverkusen Guanidin - derivate
GB8401751D0 (en) * 1984-01-24 1984-02-29 Ici Plc Guanidine derivatives
DE3532880A1 (de) * 1985-09-14 1987-03-26 Basf Ag 1,4-disubstituierte pyrazolderivate
KR900008756B1 (en) * 1987-05-27 1990-11-29 Mitsubishi Electric Corp Amplifier
GB9125970D0 (en) * 1991-12-06 1992-02-05 Fujisawa Pharmaceutical Co New compounds
AR091516A1 (es) 2012-06-22 2015-02-11 Actelion Pharmaceuticals Ltd Derivados de 1-[m-carboxamido(hetero)aril-metil]-heterociclil-carboxamida
EP4196793A1 (en) 2020-08-11 2023-06-21 Université de Strasbourg H2 blockers targeting liver macrophages for the prevention and treatment of liver disease and cancer

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4117131A (en) * 1976-12-07 1978-09-26 Warner-Lambert Company Method of inhibiting gastric acid secretions with 2-(4-pyrimidinyl)thioacetamides
US4248784A (en) * 1977-02-25 1981-02-03 Sterling Drug Inc. Pyrrole-3-acetamides
US4165378A (en) * 1977-04-20 1979-08-21 Ici Americas Inc. Guanidine derivatives of imidazoles and thiazoles
IE47044B1 (en) * 1977-04-20 1983-12-14 Ici Ltd Guanidine derivatives
JPS5444660A (en) * 1977-08-29 1979-04-09 Yamanouchi Pharmaceut Co Ltd Heterocyclic compound and its preparation
EP0003640B1 (en) * 1978-01-18 1982-01-27 Imperial Chemical Industries Plc Antisecretory guanidine derivatives, processes for their manufacture and pharmaceutical compositions containing them
EP0006679B1 (en) * 1978-05-24 1982-07-21 Imperial Chemical Industries Plc Antisecretory thiadiazole derivatives, processes for their manufacture and pharmaceutical compositions containing them
US4309435A (en) * 1978-10-16 1982-01-05 Imperial Chemical Industries Ltd. Antisecretory guanidine derivatives and pharmaceutical compositions containing them
PH16099A (en) * 1979-03-06 1983-06-24 Yamanouchi Pharma Co Ltd Guanidinothiazole compounds,process for preparing them and medical composition containing them
US4242351A (en) * 1979-05-07 1980-12-30 Imperial Chemical Industries Limited Antisecretory oxadiazoles and pharmaceutical compositions containing them
GR71929B (fi) * 1979-11-13 1983-08-19 Ici Ltd
CA1233818A (en) * 1981-03-09 1988-03-08 David J. Gilman Guanidine derivatives as histamine h-2 receptor antagonists
IN158869B (fi) * 1981-03-18 1987-02-07 Ici Plc
US4451463A (en) * 1981-03-24 1984-05-29 Imperial Chemical Industries Plc Alcohol derivatives

Also Published As

Publication number Publication date
AU582492B2 (en) 1989-03-23
PL235333A1 (en) 1983-03-28
ES518704A0 (es) 1984-02-01
ZW4182A1 (en) 1983-10-26
PT74548B (en) 1983-11-10
ES518706A0 (es) 1984-02-01
IN160139B (fi) 1987-06-27
PT74548A (en) 1982-04-01
ES510258A0 (es) 1983-04-16
DD202551A5 (de) 1983-09-21
PL138527B1 (en) 1986-09-30
DK101882A (da) 1982-09-10
EP0060094B1 (en) 1986-01-22
EP0060094A3 (en) 1982-11-17
AU582948B2 (en) 1989-04-13
ES8402563A1 (es) 1984-02-01
IE820518L (en) 1982-09-09
IL65216A (en) 1987-12-20
ES8402561A1 (es) 1984-02-01
ES518705A0 (es) 1984-02-01
AU6889387A (en) 1987-05-14
CA1233818A (en) 1988-03-08
ES8402580A1 (es) 1984-02-01
NO820726L (no) 1982-09-10
AU560043B2 (en) 1987-03-26
DE3268615D1 (en) 1986-03-06
EP0060094A2 (en) 1982-09-15
ES8305707A1 (es) 1983-04-16
AU8117282A (en) 1982-09-16
NZ199941A (en) 1985-05-31
YU49482A (en) 1985-04-30
IE52719B1 (en) 1988-02-03
ES518707A0 (es) 1984-02-01
US4447441A (en) 1984-05-08
US4665073A (en) 1987-05-12
GR74750B (fi) 1984-07-11
AU6889487A (en) 1987-05-14
ES8402562A1 (es) 1984-02-01

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Legal Events

Date Code Title Description
FD Application lapsed

Owner name: ICI AMERICAS INC

Owner name: IMPERIAL CHEMICAL INDUSTRIES PLC