ES518705A0 - Procedimiento para preparar derivados de guanidina. - Google Patents
Procedimiento para preparar derivados de guanidina.Info
- Publication number
- ES518705A0 ES518705A0 ES518705A ES518705A ES518705A0 ES 518705 A0 ES518705 A0 ES 518705A0 ES 518705 A ES518705 A ES 518705A ES 518705 A ES518705 A ES 518705A ES 518705 A0 ES518705 A0 ES 518705A0
- Authority
- ES
- Spain
- Prior art keywords
- procedure
- guanidine derivatives
- preparing guanidine
- preparing
- derivatives
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/72—Nitrogen atoms
- C07D213/76—Nitrogen atoms to which a second hetero atom is attached
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
- C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D231/14—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D231/38—Nitrogen atoms
- C07D231/40—Acylated on said nitrogen atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/32—One oxygen, sulfur or nitrogen atom
- C07D239/42—One nitrogen atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
- C07D239/47—One nitrogen atom and one oxygen or sulfur atom, e.g. cytosine
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
- C07D241/02—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings
- C07D241/10—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
- C07D241/14—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D241/20—Nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
- C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
- C07D249/04—1,2,3-Triazoles; Hydrogenated 1,2,3-triazoles
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
- C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
- C07D249/04—1,2,3-Triazoles; Hydrogenated 1,2,3-triazoles
- C07D249/06—1,2,3-Triazoles; Hydrogenated 1,2,3-triazoles with aryl radicals directly attached to ring atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
- C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
- C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
- C07D249/10—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D249/14—Nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D251/00—Heterocyclic compounds containing 1,3,5-triazine rings
- C07D251/02—Heterocyclic compounds containing 1,3,5-triazine rings not condensed with other rings
- C07D251/12—Heterocyclic compounds containing 1,3,5-triazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
- C07D251/14—Heterocyclic compounds containing 1,3,5-triazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hydrogen or carbon atoms directly attached to at least one ring carbon atom
- C07D251/16—Heterocyclic compounds containing 1,3,5-triazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hydrogen or carbon atoms directly attached to at least one ring carbon atom to only one ring carbon atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D277/38—Nitrogen atoms
- C07D277/44—Acylated amino or imino radicals
- C07D277/48—Acylated amino or imino radicals by radicals derived from carbonic acid, or sulfur or nitrogen analogues thereof, e.g. carbonylguanidines
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB8107273 | 1981-03-09 | ||
| GB8128179 | 1981-09-17 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| ES8402562A1 ES8402562A1 (es) | 1984-02-01 |
| ES518705A0 true ES518705A0 (es) | 1984-02-01 |
Family
ID=26278698
Family Applications (5)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES510258A Granted ES510258A0 (es) | 1981-03-09 | 1982-03-09 | Procedimiento para preparar derivados de quanadina. |
| ES518706A Granted ES518706A0 (es) | 1981-03-09 | 1982-12-30 | Procedimiento para preparar derivados de guanidina. |
| ES518704A Expired ES8402561A1 (es) | 1981-03-09 | 1982-12-30 | Procedimiento para preparar derivados de guanidina. |
| ES518705A Granted ES518705A0 (es) | 1981-03-09 | 1982-12-30 | Procedimiento para preparar derivados de guanidina. |
| ES518707A Expired ES8402580A1 (es) | 1981-03-09 | 1982-12-30 | Procedimiento para preparar un derivado de guanidina |
Family Applications Before (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES510258A Granted ES510258A0 (es) | 1981-03-09 | 1982-03-09 | Procedimiento para preparar derivados de quanadina. |
| ES518706A Granted ES518706A0 (es) | 1981-03-09 | 1982-12-30 | Procedimiento para preparar derivados de guanidina. |
| ES518704A Expired ES8402561A1 (es) | 1981-03-09 | 1982-12-30 | Procedimiento para preparar derivados de guanidina. |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES518707A Expired ES8402580A1 (es) | 1981-03-09 | 1982-12-30 | Procedimiento para preparar un derivado de guanidina |
Country Status (19)
| Country | Link |
|---|---|
| US (2) | US4447441A (es) |
| EP (1) | EP0060094B1 (es) |
| AU (3) | AU560043B2 (es) |
| CA (1) | CA1233818A (es) |
| DD (1) | DD202551A5 (es) |
| DE (1) | DE3268615D1 (es) |
| DK (1) | DK101882A (es) |
| ES (5) | ES510258A0 (es) |
| FI (1) | FI820795L (es) |
| GR (1) | GR74750B (es) |
| IE (1) | IE52719B1 (es) |
| IL (1) | IL65216A (es) |
| IN (1) | IN160139B (es) |
| NO (1) | NO820726L (es) |
| NZ (1) | NZ199941A (es) |
| PL (1) | PL138527B1 (es) |
| PT (1) | PT74548B (es) |
| YU (1) | YU49482A (es) |
| ZW (1) | ZW4182A1 (es) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA1233818A (en) * | 1981-03-09 | 1988-03-08 | David J. Gilman | Guanidine derivatives as histamine h-2 receptor antagonists |
| EP0103390A3 (en) * | 1982-08-13 | 1986-02-26 | Imperial Chemical Industries Plc | Guanidine-containing esters as histamine h2 receptor blockers |
| GB8320820D0 (en) * | 1982-09-03 | 1983-09-01 | Ici Plc | Polymorphs |
| GB8316779D0 (en) * | 1982-09-07 | 1983-07-27 | Ici Plc | Process |
| DE3334455A1 (de) * | 1983-03-04 | 1984-09-06 | Bayer Ag, 5090 Leverkusen | Guanidin - derivate |
| GB8401751D0 (en) * | 1984-01-24 | 1984-02-29 | Ici Plc | Guanidine derivatives |
| DE3532880A1 (de) * | 1985-09-14 | 1987-03-26 | Basf Ag | 1,4-disubstituierte pyrazolderivate |
| GB2205210B (en) * | 1987-05-27 | 1991-04-24 | Mitsubishi Electric Corp | Amplifier circuit including single capacitor for dc differential-input balance |
| GB9125970D0 (en) * | 1991-12-06 | 1992-02-05 | Fujisawa Pharmaceutical Co | New compounds |
| AR091516A1 (es) | 2012-06-22 | 2015-02-11 | Actelion Pharmaceuticals Ltd | Derivados de 1-[m-carboxamido(hetero)aril-metil]-heterociclil-carboxamida |
| WO2022034121A1 (en) | 2020-08-11 | 2022-02-17 | Université De Strasbourg | H2 blockers targeting liver macrophages for the prevention and treatment of liver disease and cancer |
Family Cites Families (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4117131A (en) * | 1976-12-07 | 1978-09-26 | Warner-Lambert Company | Method of inhibiting gastric acid secretions with 2-(4-pyrimidinyl)thioacetamides |
| US4248784A (en) * | 1977-02-25 | 1981-02-03 | Sterling Drug Inc. | Pyrrole-3-acetamides |
| NZ186965A (en) * | 1977-04-20 | 1980-02-21 | Ici Ltd | Guanidino derivatives and pharmaceutical compositions |
| US4165378A (en) * | 1977-04-20 | 1979-08-21 | Ici Americas Inc. | Guanidine derivatives of imidazoles and thiazoles |
| JPS5444660A (en) * | 1977-08-29 | 1979-04-09 | Yamanouchi Pharmaceut Co Ltd | Heterocyclic compound and its preparation |
| JPS54132566A (en) * | 1978-01-18 | 1979-10-15 | Ici Ltd | Guanidine derivative*its manufacture and secretion controlling pharmaceutical composition containing it |
| EP0006679B1 (en) * | 1978-05-24 | 1982-07-21 | Imperial Chemical Industries Plc | Antisecretory thiadiazole derivatives, processes for their manufacture and pharmaceutical compositions containing them |
| US4309435A (en) * | 1978-10-16 | 1982-01-05 | Imperial Chemical Industries Ltd. | Antisecretory guanidine derivatives and pharmaceutical compositions containing them |
| PH16099A (en) * | 1979-03-06 | 1983-06-24 | Yamanouchi Pharma Co Ltd | Guanidinothiazole compounds,process for preparing them and medical composition containing them |
| US4242351A (en) * | 1979-05-07 | 1980-12-30 | Imperial Chemical Industries Limited | Antisecretory oxadiazoles and pharmaceutical compositions containing them |
| GR71929B (es) * | 1979-11-13 | 1983-08-19 | Ici Ltd | |
| CA1233818A (en) * | 1981-03-09 | 1988-03-08 | David J. Gilman | Guanidine derivatives as histamine h-2 receptor antagonists |
| IN158869B (es) * | 1981-03-18 | 1987-02-07 | Ici Plc | |
| US4451463A (en) * | 1981-03-24 | 1984-05-29 | Imperial Chemical Industries Plc | Alcohol derivatives |
-
1982
- 1982-02-23 CA CA000396836A patent/CA1233818A/en not_active Expired
- 1982-03-01 US US06/353,502 patent/US4447441A/en not_active Expired - Fee Related
- 1982-03-04 EP EP82301106A patent/EP0060094B1/en not_active Expired
- 1982-03-04 DE DE8282301106T patent/DE3268615D1/de not_active Expired
- 1982-03-05 AU AU81172/82A patent/AU560043B2/en not_active Ceased
- 1982-03-05 PL PL1982235333A patent/PL138527B1/pl unknown
- 1982-03-08 YU YU00494/82A patent/YU49482A/xx unknown
- 1982-03-08 NO NO820726A patent/NO820726L/no unknown
- 1982-03-08 FI FI820795A patent/FI820795L/fi not_active Application Discontinuation
- 1982-03-08 DD DD82238277A patent/DD202551A5/de unknown
- 1982-03-08 IN IN193/DEL/82A patent/IN160139B/en unknown
- 1982-03-08 NZ NZ199941A patent/NZ199941A/en unknown
- 1982-03-08 ZW ZW41/82A patent/ZW4182A1/xx unknown
- 1982-03-08 PT PT74548A patent/PT74548B/pt unknown
- 1982-03-08 GR GR67522A patent/GR74750B/el unknown
- 1982-03-08 IE IE518/82A patent/IE52719B1/en unknown
- 1982-03-09 ES ES510258A patent/ES510258A0/es active Granted
- 1982-03-09 DK DK101882A patent/DK101882A/da not_active Application Discontinuation
- 1982-03-10 IL IL65216A patent/IL65216A/xx unknown
- 1982-12-30 ES ES518706A patent/ES518706A0/es active Granted
- 1982-12-30 ES ES518704A patent/ES8402561A1/es not_active Expired
- 1982-12-30 ES ES518705A patent/ES518705A0/es active Granted
- 1982-12-30 ES ES518707A patent/ES8402580A1/es not_active Expired
-
1984
- 1984-03-14 US US06/589,345 patent/US4665073A/en not_active Expired - Fee Related
-
1987
- 1987-02-17 AU AU68893/87A patent/AU582492B2/en not_active Ceased
- 1987-02-17 AU AU68894/87A patent/AU582948B2/en not_active Ceased
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