FI782202A - Nya tetralinderivat deras framstaellning och anvaendning - Google Patents

Nya tetralinderivat deras framstaellning och anvaendning

Info

Publication number
FI782202A
FI782202A FI782202A FI782202A FI782202A FI 782202 A FI782202 A FI 782202A FI 782202 A FI782202 A FI 782202A FI 782202 A FI782202 A FI 782202A FI 782202 A FI782202 A FI 782202A
Authority
FI
Finland
Prior art keywords
tetral
lines
deras framstaellning
framstaellning och
och anvaendning
Prior art date
Application number
FI782202A
Other languages
English (en)
Other versions
FI68821C (fi
FI68821B (fi
Inventor
Max-Peter Seiler
Original Assignee
Sandoz Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sandoz Ag filed Critical Sandoz Ag
Publication of FI782202A publication Critical patent/FI782202A/fi
Application granted granted Critical
Publication of FI68821B publication Critical patent/FI68821B/fi
Publication of FI68821C publication Critical patent/FI68821C/fi

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D239/00Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/32One oxygen, sulfur or nitrogen atom
    • C07D239/42One nitrogen atom
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/72Nitrogen atoms
    • C07D213/74Amino or imino radicals substituted by hydrocarbon or substituted hydrocarbon radicals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D233/00Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/66Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/88Nitrogen atoms, e.g. allantoin
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D277/00Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/32Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D277/38Nitrogen atoms
    • C07D277/42Amino or imino radicals substituted by hydrocarbon or substituted hydrocarbon radicals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D295/00Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/08Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
    • C07D295/096Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D317/00Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D317/08Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
    • C07D317/44Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D317/46Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems condensed with one six-membered ring
    • C07D317/48Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring
    • C07D317/62Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to atoms of the carbocyclic ring
    • C07D317/66Nitrogen atoms not forming part of a nitro radical

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Heterocyclic Compounds That Contain Two Or More Ring Oxygen Atoms (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
FI782202A 1977-07-18 1978-07-10 Analogifoerfarande foer framstaellning av nya tetralinderivat vilka saenker blodtryck och oekar blodetsgenomstroemning FI68821C (fi)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
CH886377 1977-07-18
CH886377 1977-07-18
CH1358377 1977-11-08
CH1358377 1977-11-08

Publications (3)

Publication Number Publication Date
FI782202A true FI782202A (fi) 1979-01-19
FI68821B FI68821B (fi) 1985-07-31
FI68821C FI68821C (fi) 1985-11-11

Family

ID=25703869

Family Applications (1)

Application Number Title Priority Date Filing Date
FI782202A FI68821C (fi) 1977-07-18 1978-07-10 Analogifoerfarande foer framstaellning av nya tetralinderivat vilka saenker blodtryck och oekar blodetsgenomstroemning

Country Status (17)

Country Link
US (1) US4308266A (fi)
EP (1) EP0000395B1 (fi)
JP (1) JPS5422383A (fi)
AU (1) AU521642B2 (fi)
CA (1) CA1131641A (fi)
CY (1) CY1224A (fi)
DE (1) DE2860410D1 (fi)
DK (1) DK309678A (fi)
ES (2) ES471809A1 (fi)
FI (1) FI68821C (fi)
HK (1) HK85184A (fi)
IE (1) IE47129B1 (fi)
IL (1) IL55153A (fi)
IT (1) IT1105089B (fi)
NZ (1) NZ187876A (fi)
PH (1) PH17238A (fi)
PT (1) PT68306A (fi)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4590274A (en) * 1985-01-03 1986-05-20 E. I. Du Pont De Nemours And Company Antihypertensive 1-[bis-(substituted phenyl)methyl]-4[2-(1,2,3,4-tetrahydro-substituted naphthalen-1-ylidene)ethyl]piperazines
GB8615560D0 (en) * 1986-06-25 1986-07-30 Maggioni Farma Aminoalcohols
WO1987002035A1 (en) * 1985-10-04 1987-04-09 Maggioni-Winthrop S.P.A. Fused cycloaliphatic aminoalcohols
IL85700A0 (en) * 1987-03-24 1988-08-31 Takeda Chemical Industries Ltd 1,4-disubstituted piperazine compounds,their production and use
US4845221A (en) * 1988-04-15 1989-07-04 American Home Products Corporation Serotonergic substituted piperazinyl tetralins
CA1335591C (en) * 1988-05-23 1995-05-16 James Arthur Nixon Ring-substituted 2-amino-1,2,3,4-tetrahydronaphthalenes
US4988699A (en) * 1989-03-14 1991-01-29 Warner-Lambert Company Substituted tetrahydrobenzothiazoles as dopaminergic agents
GB8907865D0 (en) * 1989-04-07 1989-05-24 Wyeth John & Brother Ltd Tetrahydroquinoline derivatives
US5194439A (en) * 1990-04-06 1993-03-16 John Wyeth & Brother Limited N-(2,3-dihydro-1,4-benzodioxinyl)-N-substituted aminopyrido-fused cycloalkanes
GB2290790A (en) * 1994-06-30 1996-01-10 Merck & Co Inc Asymmetric synthesis of 6-substituted 2-amino-1,2,3,4-tetrahydronaphthalenes

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1190466B (de) * 1961-11-07 1965-04-08 Cassella Farbwerke Mainkur Ag Verfahren zur Herstellung von Piperazinderivaten
CA969955A (en) * 1970-07-20 1975-06-24 Rene Viterbo Dihydronaphthalene derivatives
US4018773A (en) * 1975-09-15 1977-04-19 E. R. Squibb & Sons, Inc. Phenylpiperazinotetrahydronaphthols and derivatives

Also Published As

Publication number Publication date
IT1105089B (it) 1985-10-28
JPS5422383A (en) 1979-02-20
IL55153A (en) 1983-07-31
ES471809A1 (es) 1979-10-01
HK85184A (en) 1984-11-16
DK309678A (da) 1979-01-19
AU3808678A (en) 1980-01-17
NZ187876A (en) 1981-02-11
FI68821C (fi) 1985-11-11
AU521642B2 (en) 1982-04-22
CY1224A (en) 1984-04-06
PT68306A (fr) 1978-08-01
ES479059A1 (es) 1979-07-01
IE47129B1 (en) 1983-12-28
IT7850272A0 (it) 1978-07-13
PH17238A (en) 1984-07-03
IL55153A0 (en) 1978-09-29
EP0000395B1 (de) 1981-01-07
CA1131641A (en) 1982-09-14
DE2860410D1 (en) 1981-02-26
US4308266A (en) 1981-12-29
IE781438L (en) 1979-01-18
FI68821B (fi) 1985-07-31
EP0000395A1 (de) 1979-01-24

Similar Documents

Publication Publication Date Title
FI780801A (fi) Nya cefem- och cefam-kompositioner och foerfarande foer deras framstaellning
FI783867A (fi) Nya 4-hydroxi-2h-1 2-benzotiatsin-3-karboxamid-1 1-dioxider deras framstaellningsfoerfarande deras anvaendning och dessa foereningar innehaollande laekemedel
FI781811A (fi) Nya carbostyrilderivat
FI782931A (fi) Nya aemnessammansaettningar
FI782907A (fi) Nya cyklopeptider
FI772823A (fi) Nya 1-aryloxi-hydroxi-3-alkylenaminopropaner och foerfarande foer deras framstaellning
FI780589A (fi) Nya 4-acylamino-fenyl-etanolaminer
FI781933A (fi) Nya peptidderivat
SE7807642L (sv) Nya 1-acyl-2-cyanaziridiner
FI772262A (fi) Nya fenyletylaminer och foerfarande foer deras framstaellning
FI783590A (fi) Nya prostacyklinderivat och foerfarande foer deras framstaellning
FI773717A (fi) Nya aminoalkoxifenylderivater
FI782202A (fi) Nya tetralinderivat deras framstaellning och anvaendning
FI783846A (fi) Nya bredspektriga cefalosporinantibioter
FI781674A (fi) Nya fluoriderade aminosyror
SE7810050L (sv) Nya 7-azabensimidazoler
FI782215A (fi) Nya nitrosoureafoereningar och deras framstaellningsfoerfarande
FI780083A (fi) Nya ditienylalkylaminer och foerfarande foer deras framstaellning
FI783769A (fi) Nya tetrapeptider och metoder
FI782039A (fi) Nya 2-pyridyl- och 2-pyrimidylaminobensoesyror
FI782011A (fi) Nya imidazo-isokinolin-dioner
SE7804318L (sv) Nya naftyridiner
FI780772A (fi) Nya spiro-oxazolinderivat av steroider och foerfarande foer deras framstaellning
FI780594A (fi) Nya aryl-hexafuranosider och foerfarande foer deras framstaellning
FI782587A (fi) Nya 2-substituerade-3-fenylindoler och foerfarande foer deras framstaellning

Legal Events

Date Code Title Description
MM Patent lapsed

Owner name: SANDOZ AG