FI60645B - FOERFARANDE FOER FRAMSTAELLNING AV VAEXTEXTRAKT FOER SKOETSEL AV ASTMA SNUVA OCH / ELLER HOSTA - Google Patents

Description

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1 UTLÄGGNINGSSKRIFT 6 4 5 ^ 45) Patent granted on 10 03 1982, ¾¾¾ Patent oeddelat ^ (51) Kv.lk?/lnt.CI.3 A 61 K 35/78 FINLAND —FINLAND (21) Pattnttihaktmui - Patentansttkning 8θ 138 8 ( 22) H * lt * mlipSlvl - Antöknlngtdig 29.0k.80 * (23) Alkupllvt — Glltl | h «t * da | 29.0 ^ .80 (41) Become Stuck - Bllvlt offuntllg 30.10.8l

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Patent- och registerstyrelsen 'Ansökun utlugd och utl.tkriftun publicurad 30.11.8l (32) (33) (31) Pyydetty MuoUcmi * —B «glrd prloritct (71) (72) Veijo Kiiskinen, Vintturi as. 8, 7 ^ 510 Peltosalmi, Suomi-Finland (FI) (7 * 0 Papula Rein Lahtela Oy (5 ^) Method for preparing a plant extract for the treatment of asthma, rhinitis and / or cough - Förfarande för framställning av växtextrakt för skötsel av astma The invention relates to a method for preparing a plant extract as defined in the preamble of the claim.

Synthetic drugs used in the treatment of asthma and allergic rhinitis and cough cause adverse effects, due to which such drugs such as cortisone, antihistamines, etc. cannot be used continuously. Known drugs have not achieved satisfactory results in the treatment of asthma and allergic rhinitis and cough.

It is an object of the present invention to provide a process for the preparation of a new medicament for use in the treatment of asthma and rhinitis and cough, which medicament does not have the side effects of medicaments previously used in the treatment of these diseases.

With regard to the features characteristic of the invention, reference is made to 35 claims.

The invention is based on a vegetable extract prepared from the following vegetables: 2,60645

Icelandic lichen (Cetraria islandica)

Porcupine (Achillea millefolium)

Dandelion leaves (Taraxacum officinale)

Juniper berries (Fructus juniperi) 5 Potentilla erecta Equisetum fluviatile

Widow's leaf (Tussilago farfara)

Pork reel (Arctostaphylos uvaursi)

Willow bark (Salix silvestris) 10 Pine (Pinus silvestris) - annual pine tumors - fresh pine conifers

According to the method, the dried vegetables are placed in a cooking vessel and mixed with cold water, e.g. at a temperature below 10 ° C, in water. The mixture is slowly brought to a boil and the mixture is allowed to boil until all the ingredients are pressed to the bottom. The mixture is then allowed to simmer for about 1-2 hours. Fresh pine beans are mixed separately with cold water, the mixture is heated and stewed as above. The two mixtures are sieved and mixed together and filtered. To improve the preservation of the mixture, sugar may be added to the mixture.

Of these plants, the use of a widow's leaf as a cough medicine in the form of an extract from dried leaves is known (Martincle: The Extra Pharmacopoeia, 1972, p. 1494).

25 Of the other plants used, in particular Iceland lichen, pine tumors, hogweed and juniper berries have a mucus-releasing effect. Icelandic lichen is also known to have therapeutic efficacy in the treatment of intestinal disorders, especially gastric ulcer (U.S. Pat. No. 4,150,123). Furthermore, Icelandic lichen 30 is known to have a therapeutic effect in the treatment of tracheal catarrh, chronic cough and lung disease; the effect is twofold, removing mucus and sputum and promoting general well-being (Rautavaara: What our plants are suitable for, 1976, p.26-29). Porcupine, ragweed roots, dandelion leaves and juniper berries 35 have a stimulating effect on liver, kidney and intestinal function as well as general glandular function; as a result, the elimination of harmful substances from the body is accelerated.

3,60645 Lake horsetail, and juniper berries strengthen nerves and willow bark reduces pain and lowers fever. Iceland lichen, widow's leaf and lake horsetail contain silicon compounds.

Of these vegetables, Icelandic lichen is the most important due to its 5 mucus-releasing effects. However, based on the experience of its users, Icelandic lichen has side effects, headache, rash and nausea, which, however, are prevented in the medicament according to the invention due to the other ingredients contained in the vegetables used in the mixture.

The plant extract to be prepared according to the invention has proven to be excellent in the treatment of chronic and severe asthma. No adverse side effects have been observed. A beneficial therapeutic effect has also been observed in the treatment of allergies.

The plant extract to be prepared according to the invention can be dispensed internally mixed, e.g. with hot water, with a maximum dosage of 3 tablespoons of extract / 1 dl of hot water for continuous use. The plant extract acts within 10 minutes of dosing, relieving shortness of breath, cough and runny nose.

The invention will now be described in detail by means of 20 exemplary embodiments.

Example 1.

Dried vegetables: Icelandic lichen 40 g hogweed 15 g dandelion leaves 10 g 25 juniper berries 10 g ragweed roots 30 g lake leaf 10 g widow leaf 3 g pork chop 5 g 30 willow bark 10 g was placed in a saucepan and poured into 6 l of cold water. The mixture was heated to reflux and allowed to boil until all the ingredients sank to the bottom. The mixture was then allowed to incubate for 0.5 hours. 50 g of annual pine tumors frozen and 35,200 g of young pine conifers were boiled separately as described above mixed with 5 liters of cold water. Both broths were sieved and mixed together and filtered. 1 kg of sugar was added to the filtrate.

Example 2.

Dried vegetables: Icelandic lichen 4 60645 Dosage was added to 1 kg of sugar.

Example 2.

Dried vegetables: Icelandic lichen 60 g horseradish 20 g 5 dandelion leaves 20 g juniper berries 30 g ragweed roots 60 g lake leaf 30 g widow's leaf 10 g 10 hogweed 10 g willow bark 20 g mixed with 10 l of cold water, the mixture was heated to boiling and allowed to boil h time. The mixture was allowed to incubate with stirring for 0.5 h. To the mixture was added a mixture obtained by boiling 100 g of annual pine tumors and 100 g of fresh pine conifers in 10 l of water as described above. The resulting mixture was filtered to separate the solids.

Example 3.

Dried vegetables: Icelandic lichen 30 g 20 hogweed 10 g dandelion leaves 10 g juniper berries 10 g ragweed roots 10 g lake horsetail 10 g 25 widow's leaf 3 g hogweed 5 g willow bark 10 g was mixed with 7 l of cold water, the mixture was heated and allowed to boil, the detectable solid parts of plant-30 had sunk to the bottom of the cooking vessel. The mixture was allowed to simmer for about 1 h. 100 g of pine pods less than 1 year old and 50 g of annual pine tumors were mixed with 7 l of cold water, the mixture was boiled and allowed to boil until the conifers and annual tumors had sunk to the bottom of the cooking vessel. The resulting mixtures were mixed and filtered. 1 kg of sugar was added to the filtrate.

5 60645 TEST RESULTS:

Experiment 1. The patient was a nine-year-old child and had had asthma from the age of three. Previous drug treatment had not been effective. The patient was given an extract prepared according to rsinu kmi 1 mixed with 3 tablespoons / 1 dl of hot water in the event of an asthma attack. After medication, the seizure passed immediately. In the event of the next seizure, about one week from the previous one, similar medication was performed. The scene passed again. There have been no side effects after 2.5 years of drug treatment.

Experiment 2. The patient, a 30-year-old female, had suffered from a persistent rhinitis suspected of being caused by carpeting. The patient used the extract prepared according to Example 2 daily for 2 weeks, after which the rhinitis stopped, ^ dosing as in Experiment 1. Half a year after the treatment, the rhinitis has not recurred.

Experiment 3. A patient, a 70-year-old retiree, a woman, had had asthma for more than 10 years. Previous medication has not been able to move outdoors at all for years. After using 20 extracts prepared according to Example 3, the dosage as in Experiment 1, half a year, the shortness of breath ceased and the general condition improved. The patient can move around and take care of things in the city without difficulty '. Night sleep has also become calmer after starting treatment. Use the extract if necessary.

25

Experiment 4. A patient A 50-year-old farmer who had had asthma for more than five years, had previously used heart medications for heart disease, and was unable to cope with his condition’s work earlier. After starting the medication according to Experiment 1, he stopped taking other drugs and has survived his work with daily dosing. After six months of treatment with the use of heart drugs (nitrojen) had run out.

Experiment 5. Patient 76-year-old pensioner, male, with asthma for more than 10 years. Previous drug therapy was not effective in asthma. drug use during the experiment, according to one side 35 of the Jei not improved asthma is, however, easier for the patient substantially indicative of the extract, he uses the most powerful drugs.

6 60645

Experiment 6. Patient A 25-year-old farmer, male, with asthma for more than five years. During previous medication, it was not possible to handle farming properly. After using the drug, prepared according to Example 3, the dosage according to Experiment 1 for 1 year has been able to handle the agricultural work normally.

Experience 7. A 13-year-old schoolboy, suffering from asthma for several years, which hampered school attendance. After using the preparation according to Example 1, dosing according to Experiment 1, for 3 months 10, after which the well-being improved and schooling went normally, the patient has been able to participate in sports, which he was previously unable to do. After receiving the extract for the first symptoms of influenza, the symptoms of the flu had disappeared within about 8 h.

15 Experiment 8. Patient A 5-year-old boy who had suffered from a severe allergy and asthma for three years had to be in hospital often. After starting to use the extract prepared according to Example 1, the dosage according to Experiment 1, in the event of an asthma attack or the onset of allergic symptoms for 1 year, no hospitalization was required, the use of other drugs has been lower than before.

Experiment 9. Patient A 62-year-old retiree, a female person, has suffered from asthma for about 10 years, resulting in a disability pension. Started treatment with the preparation of Example 1, 25 dosages according to Experiment 1, about a year ago, when asthma eased and general condition improved. After starting treatment has been able to go outdoors in frost, temperature below -24 ° C, without any disadvantages; previously could not go outside even in frost, temperatures below -10 ° C.

30 Experiment 10. A patient A 35-year-old lady with mild asthma for more than three years had not received effective treatment before. Started treatment with the extract of Example 2 about 1 year ago, dosing as in Experiment 1, using the extract every day for one dose for two months. All 35 symptoms of asthma disappeared.

Experiment 11. Patient A 55-year-old female who had had asthma for about five years, during which time she was barely able to do any of the 7,60645 housework, began treatment with the extract of Example 3, dosing according to Experiment 1, in May 1980, when asthma began to ease immediately. After 2 months, the patient was able to perform the duties of the hostess of the agricultural holding.

5 for harvesting hay and handling dry hay this without causing him any harm.

10 15 20 25 30 35

Claims (1)

60645 8 CLAIMS A process for the preparation of a plant extract for the treatment of asthma, rhinitis and / or cough, which contains plant extracts of the widow's leaf (Tussilago farfara) and the Icelandic lichen (Cetraria islandica), known as ys-5, known as: dried vegetables: amount 30-60 g porcini (Achillea millefolium) "10-20 g 10 dandelion leaves (Taraxacum officinale)" 10-20 g juniper berries (Fructus juniperi) "10-30 g roots (Potentilla erecta)" 10-60 g lake horseradish ( Equisetum fluviatile) "10-30 g widow's leaf (Tussilago farfara)" 3-10 g 15 pork halves (Arctostaphylos uvaursi) "5-10 g willow bark (Salix phylicifolia)" 0-20 g are mixed with water at a temperature below 40 ° C, the mixture is heated to boiling and boiled; 100-200 g of annual tumors and / or fresh conifers of pine (Pinus silvestris) are mixed with water at a temperature below 40 ° C, the mixture is heated to boiling and boiled; the mixtures are combined and filtered. 25 30 35