FI60007C - Foerfarande foer framstaellning av terapeutiskt anvaendbar 3-(4-p-fluorfenyl-1-metylbutyl)-1-(4-piperidinobutyryloxi)-6,6,9-trimetyl-7,8,9,10-tetrahydro-6h-dibenso(b,d)pyran - Google Patents

Foerfarande foer framstaellning av terapeutiskt anvaendbar 3-(4-p-fluorfenyl-1-metylbutyl)-1-(4-piperidinobutyryloxi)-6,6,9-trimetyl-7,8,9,10-tetrahydro-6h-dibenso(b,d)pyran Download PDF

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Publication number
FI60007C
FI60007C FI1027/74A FI102774A FI60007C FI 60007 C FI60007 C FI 60007C FI 1027/74 A FI1027/74 A FI 1027/74A FI 102774 A FI102774 A FI 102774A FI 60007 C FI60007 C FI 60007C
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FI
Finland
Prior art keywords
fluorophenyl
tetrahydro
methyl
methylbutyl
pyran
Prior art date
Application number
FI1027/74A
Other languages
English (en)
Finnish (fi)
Other versions
FI60007B (fi
Inventor
Martin Winn
Original Assignee
Abbott Lab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Abbott Lab filed Critical Abbott Lab
Application granted granted Critical
Publication of FI60007B publication Critical patent/FI60007B/fi
Publication of FI60007C publication Critical patent/FI60007C/fi

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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D295/00Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/14Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D295/145Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with the ring nitrogen atoms and the carbon atoms with three bonds to hetero atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
    • C07D295/15Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with the ring nitrogen atoms and the carbon atoms with three bonds to hetero atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C37/00Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom of a six-membered aromatic ring
    • C07C37/01Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom of a six-membered aromatic ring by replacing functional groups bound to a six-membered aromatic ring by hydroxy groups, e.g. by hydrolysis
    • C07C37/055Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom of a six-membered aromatic ring by replacing functional groups bound to a six-membered aromatic ring by hydroxy groups, e.g. by hydrolysis the substituted group being bound to oxygen, e.g. ether group
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D295/00Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/14Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D311/00Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/78Ring systems having three or more relevant rings
    • C07D311/80Dibenzopyrans; Hydrogenated dibenzopyrans
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D311/00Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/94Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems condensed with rings other than six-membered or with ring systems containing such rings

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pyrane Compounds (AREA)
FI1027/74A 1973-04-05 1974-04-03 Foerfarande foer framstaellning av terapeutiskt anvaendbar 3-(4-p-fluorfenyl-1-metylbutyl)-1-(4-piperidinobutyryloxi)-6,6,9-trimetyl-7,8,9,10-tetrahydro-6h-dibenso(b,d)pyran FI60007C (fi)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US34837173A 1973-04-05 1973-04-05
US34837173 1973-04-05
US05/442,033 US4049653A (en) 1973-04-05 1974-02-13 Heterocyclic esters of alkylphenyl benzopyrans
US44203374 1974-02-13

Publications (2)

Publication Number Publication Date
FI60007B FI60007B (fi) 1981-07-31
FI60007C true FI60007C (fi) 1981-11-10

Family

ID=26995674

Family Applications (1)

Application Number Title Priority Date Filing Date
FI1027/74A FI60007C (fi) 1973-04-05 1974-04-03 Foerfarande foer framstaellning av terapeutiskt anvaendbar 3-(4-p-fluorfenyl-1-metylbutyl)-1-(4-piperidinobutyryloxi)-6,6,9-trimetyl-7,8,9,10-tetrahydro-6h-dibenso(b,d)pyran

Country Status (13)

Country Link
US (1) US4049653A (no)
JP (1) JPS5035169A (no)
AU (1) AU476698B2 (no)
CA (1) CA1038383A (no)
CH (1) CH592086A5 (no)
DE (1) DE2416491C3 (no)
FI (1) FI60007C (no)
FR (1) FR2224157B1 (no)
GB (1) GB1459943A (no)
NL (1) NL7404147A (no)
NO (1) NO141341C (no)
PH (1) PH13583A (no)
SE (1) SE413191B (no)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2615397A1 (de) * 1976-04-08 1977-10-27 Sharps Ass Neue benzopyranester
US4133819A (en) * 1977-06-17 1979-01-09 Pfizer Inc. Hexahydro-1-hydroxy-9-hydroxymethyl-3-substituted-6H-dibenzo[b,d]pyrans as analgesic agents
US4243674A (en) * 1978-06-12 1981-01-06 Pfizer Inc. 9-Hydroxydibenzo[b,d]pyrans and intermediates therefore
US4454144A (en) * 1982-06-21 1984-06-12 Pfizer Inc. Substituted dibenzo[b,d]pyran analgesics
US5498419A (en) * 1994-06-03 1996-03-12 Pars; Harry G. Fumarate salt of 4-(diethyl-3-(1-methyloctyl)-7,8,9,10-tetrahydro-6,6,9-trimethyl-6H-dibenzo[b,d]pyran-1-ol, 4-(diethyl-amino) butyric
DE19706903A1 (de) 1997-02-21 1998-08-27 Bayer Ag Verwendung von bekannten Agonisten des zentralen Cannabinoid-Rezeptors CB 1
US6187203B1 (en) * 1998-12-01 2001-02-13 Academia Sinica Sample purification apparatus and method
CN101677931B (zh) * 2007-03-16 2013-01-02 株式会社资生堂 皱纹防止、改善剂

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3880885A (en) * 1971-11-23 1975-04-29 Sandoz Ag Tertiary aminoethyl isochromans and isocoumarins
US3984419A (en) 1972-06-21 1976-10-05 E. R. Squibb & Sons, Inc. Perhydrofluorenetetrol and perhydro-phenanthrenetetrol derivatives

Also Published As

Publication number Publication date
CA1038383A (en) 1978-09-12
CH592086A5 (no) 1977-10-14
DE2416491A1 (de) 1974-10-24
NO141341B (no) 1979-11-12
FR2224157A1 (no) 1974-10-31
NL7404147A (no) 1974-10-08
PH13583A (en) 1980-07-16
SE413191B (sv) 1980-04-28
NO141341C (no) 1980-02-20
JPS5035169A (no) 1975-04-03
NO741142L (no) 1974-10-08
US4049653A (en) 1977-09-20
DE2416491B2 (de) 1979-06-28
GB1459943A (en) 1976-12-31
FI60007B (fi) 1981-07-31
AU6664974A (en) 1975-09-18
DE2416491C3 (de) 1981-01-15
AU476698B2 (en) 1976-09-30
FR2224157B1 (no) 1977-05-06

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