FI54919C - Foerfarande foer framstaellning av blodtryckssaenkande bensylimidazolidinoner - Google Patents

Foerfarande foer framstaellning av blodtryckssaenkande bensylimidazolidinoner

Info

Publication number
FI54919C
FI54919C FI501/71A FI50171A FI54919C FI 54919 C FI54919 C FI 54919C FI 501/71 A FI501/71 A FI 501/71A FI 50171 A FI50171 A FI 50171A FI 54919 C FI54919 C FI 54919C
Authority
FI
Finland
Prior art keywords
frame tractor
tractor
frame
Prior art date
Application number
FI501/71A
Other languages
English (en)
Finnish (fi)
Other versions
FI54919B (fi
Inventor
Vsevolod Gruenman
Max Hoffer
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of FI54919B publication Critical patent/FI54919B/fi
Application granted granted Critical
Publication of FI54919C publication Critical patent/FI54919C/fi

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00—Carboxylic acid nitriles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
    • C07C45/67—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton
    • C07C45/68—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms
    • C07C45/70—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms by reaction with functional groups containing oxygen only in singly bound form
    • C07C45/71—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms by reaction with functional groups containing oxygen only in singly bound form being hydroxy groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C47/00—Compounds having —CHO groups
    • C07C47/52—Compounds having —CHO groups bound to carbon atoms of six—membered aromatic rings
    • C07C47/575—Compounds having —CHO groups bound to carbon atoms of six—membered aromatic rings containing ether groups, groups, groups, or groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/04—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D233/28—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/30—Oxygen or sulfur atoms
    • C07D233/32—One oxygen atom

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
FI501/71A 1970-02-24 1971-02-22 Foerfarande foer framstaellning av blodtryckssaenkande bensylimidazolidinoner FI54919C (fi)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US1376970A 1970-02-24 1970-02-24

Publications (2)

Publication Number Publication Date
FI54919B FI54919B (fi) 1978-12-29
FI54919C true FI54919C (fi) 1979-04-10

Family

ID=21761656

Family Applications (1)

Application Number Title Priority Date Filing Date
FI501/71A FI54919C (fi) 1970-02-24 1971-02-22 Foerfarande foer framstaellning av blodtryckssaenkande bensylimidazolidinoner

Country Status (18)

Country Link
US (1) US3636039A (da)
JP (1) JPS5421338B1 (da)
BE (1) BE763298A (da)
BR (1) BR7101125D0 (da)
CA (1) CA967163A (da)
CH (2) CH567483A5 (da)
DE (1) DE2108438C2 (da)
DK (2) DK134601B (da)
FI (1) FI54919C (da)
FR (1) FR2081537B1 (da)
GB (1) GB1292768A (da)
IE (1) IE35283B1 (da)
IL (1) IL36237A (da)
NL (1) NL171446C (da)
NO (1) NO130680C (da)
SE (1) SE369190B (da)
YU (1) YU34407B (da)
ZA (1) ZA711077B (da)

Families Citing this family (32)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3932452A (en) * 1975-02-07 1976-01-13 Morton-Norwich Products, Inc. 1-Arylmethyl-2-imidazolidinones
US3966758A (en) * 1975-06-16 1976-06-29 Morton-Norwich Products, Inc. Anti-inflammatory 1-(substituted benzyl)-2-imidazolidinones
US4063022A (en) * 1976-11-22 1977-12-13 Morton-Norwich Products, Inc. Antisecretory 2-imidazolidinones
HU179019B (en) * 1978-11-01 1982-08-28 Gyogyszekutato Intezet Process for preparing 4-//3,4-dialkoxy-phenyl/-alkyl/- 2imidazolidinone derivatives
CA1188616A (en) * 1981-06-11 1985-06-11 Hoffmann-La Roche Limited Pharmaceutical preparations
US5459145A (en) * 1988-01-19 1995-10-17 Pfizer Inc. Calcium independent camp phosphodiesterase inhibitor antidepressant
WO1987006576A1 (en) * 1986-04-29 1987-11-05 Pfizer Inc. Calcium independent camp phosphodiesterase inhibitor antidepressant
US5395935A (en) * 1992-05-08 1995-03-07 Pfizer Inc. Endo-bicyclo[2.2.1]heptan-2-ol and derived pharmaceutical agents
GB9312853D0 (en) * 1993-06-22 1993-08-04 Euro Celtique Sa Chemical compounds
US5922751A (en) * 1994-06-24 1999-07-13 Euro-Celtique, S.A. Aryl pyrazole compound for inhibiting phosphodiesterase IV and methods of using same
US5591776A (en) * 1994-06-24 1997-01-07 Euro-Celtique, S.A. Pheynl or benzyl-substituted rolipram-based compounds for and method of inhibiting phosphodiesterase IV
AU4527896A (en) * 1994-12-13 1996-07-03 Euro-Celtique S.A. Aryl thioxanthines
US6025361A (en) * 1994-12-13 2000-02-15 Euro-Celtique, S.A. Trisubstituted thioxanthines
ATE247655T1 (de) * 1994-12-13 2003-09-15 Euro Celtique Sa Dreifachsubstituierte thioxanthine
US6166041A (en) * 1995-10-11 2000-12-26 Euro-Celtique, S.A. 2-heteroaryl and 2-heterocyclic benzoxazoles as PDE IV inhibitors for the treatment of asthma
US6075016A (en) * 1996-04-10 2000-06-13 Euro-Celtique S.A. 6,5-fused aromatic ring systems having enhanced phosphodiesterase IV inhibitory activity
US5864037A (en) 1996-06-06 1999-01-26 Euro-Celtique, S.A. Methods for the synthesis of chemical compounds having PDE-IV inhibitory activity
US5744473A (en) * 1996-09-16 1998-04-28 Euro-Celtique, S.A. PDE IV inhibitors: "bis-compounds"
EP1265861A2 (en) 2000-03-16 2002-12-18 Inflazyme Pharmaceuticals, Ltd. Benzylated pde4 inhibitors
US7772188B2 (en) 2003-01-28 2010-08-10 Ironwood Pharmaceuticals, Inc. Methods and compositions for the treatment of gastrointestinal disorders
US20100120694A1 (en) 2008-06-04 2010-05-13 Synergy Pharmaceuticals, Inc. Agonists of Guanylate Cyclase Useful for the Treatment of Gastrointestinal Disorders, Inflammation, Cancer and Other Disorders
US8969514B2 (en) 2007-06-04 2015-03-03 Synergy Pharmaceuticals, Inc. Agonists of guanylate cyclase useful for the treatment of hypercholesterolemia, atherosclerosis, coronary heart disease, gallstone, obesity and other cardiovascular diseases
CA3089569C (en) 2007-06-04 2023-12-05 Synergy Pharmaceuticals Inc. Agonists of guanylate cyclase useful for the treatment of gastrointestinal disorders, inflammation, cancer and other disorders
EP2321341B1 (en) 2008-07-16 2017-02-22 Synergy Pharmaceuticals Inc. Agonists of guanylate cyclase useful for the treatment of gastrointestinal, inflammation, cancer and other disorders
US9616097B2 (en) 2010-09-15 2017-04-11 Synergy Pharmaceuticals, Inc. Formulations of guanylate cyclase C agonists and methods of use
CN108676076A (zh) 2011-03-01 2018-10-19 辛纳吉制药公司 制备鸟苷酸环化酶c激动剂的方法
JP6499591B2 (ja) 2013-02-25 2019-04-10 シナジー ファーマシューティカルズ インコーポレイテッド 結腸洗浄において用いるためのグアニル酸シクラーゼ受容体アゴニスト
EP2970384A1 (en) 2013-03-15 2016-01-20 Synergy Pharmaceuticals Inc. Agonists of guanylate cyclase and their uses
JP2016514670A (ja) 2013-03-15 2016-05-23 シナジー ファーマシューティカルズ インコーポレイテッド 他の薬物と組み合わせたグアニル酸シクラーゼ受容体アゴニスト
RS65632B1 (sr) 2013-06-05 2024-07-31 Bausch Health Ireland Ltd Ultra-prečišćeni agonisti guanilat-ciklaze c, postupak njihove pripreme i upotrebe
WO2015021358A2 (en) 2013-08-09 2015-02-12 Dominique Charmot Compounds and methods for inhibiting phosphate transport
JP2022533251A (ja) 2019-05-21 2022-07-21 アルデリックス， インコーポレイテッド 患者において血清リン酸塩を低下させるための組み合わせ

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH518285A (de) * 1968-05-01 1972-01-31 Hoffmann La Roche Verfahren zur Herstellung von neuen substituierten Benzylimidazolidinonen

Also Published As

Publication number Publication date
IL36237A0 (en) 1971-04-28
BE763298A (fr) 1971-08-23
FR2081537A1 (da) 1971-12-03
DE2108438A1 (de) 1971-09-09
IL36237A (en) 1974-11-29
YU34407B (en) 1979-07-10
ZA711077B (en) 1971-10-27
BR7101125D0 (pt) 1973-04-26
CH567482A5 (da) 1975-10-15
FR2081537B1 (da) 1974-08-23
CH567483A5 (da) 1975-10-15
NO130680B (da) 1974-10-14
CA967163A (en) 1975-05-06
NL7102324A (da) 1971-08-26
DK134601B (da) 1976-12-06
IE35283B1 (en) 1976-01-07
YU43971A (en) 1978-12-31
JPS5421338B1 (da) 1979-07-30
NL171446B (nl) 1982-11-01
US3636039A (en) 1972-01-18
FI54919B (fi) 1978-12-29
SE369190B (da) 1974-08-12
NO130680C (da) 1975-01-22
NL171446C (nl) 1983-04-05
IE35283L (en) 1971-08-24
DK134601C (da) 1977-05-16
DK570075A (da) 1975-12-15
GB1292768A (en) 1972-10-11
DE2108438C2 (de) 1987-02-05

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