DK570075A - Benzylimidazolidinoner - Google Patents

Benzylimidazolidinoner

Info

Publication number
DK570075A
DK570075A DK570075A DK570075A DK570075A DK 570075 A DK570075 A DK 570075A DK 570075 A DK570075 A DK 570075A DK 570075 A DK570075 A DK 570075A DK 570075 A DK570075 A DK 570075A
Authority
DK
Denmark
Prior art keywords
benzylimidazolidinones
Prior art date
Application number
DK570075A
Other languages
English (en)
Inventor
V Gruenman
M Hoffer
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of DK570075A publication Critical patent/DK570075A/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00—Carboxylic acid nitriles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
    • C07C45/67—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton
    • C07C45/68—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms
    • C07C45/70—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms by reaction with functional groups containing oxygen only in singly bound form
    • C07C45/71—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms by reaction with functional groups containing oxygen only in singly bound form being hydroxy groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C47/00—Compounds having —CHO groups
    • C07C47/52—Compounds having —CHO groups bound to carbon atoms of six—membered aromatic rings
    • C07C47/575—Compounds having —CHO groups bound to carbon atoms of six—membered aromatic rings containing ether groups, groups, groups, or groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/04—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D233/28—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/30—Oxygen or sulfur atoms
    • C07D233/32—One oxygen atom

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
DK570075A 1970-02-24 1975-12-15 Benzylimidazolidinoner DK570075A (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US1376970A 1970-02-24 1970-02-24

Publications (1)

Publication Number Publication Date
DK570075A true DK570075A (da) 1975-12-15

Family

ID=21761656

Family Applications (2)

Application Number Title Priority Date Filing Date
DK83171AA DK134601B (da) 1970-02-24 1971-02-24 Analogifremgangsmåde til fremstilling af benzylimidazolidioner.
DK570075A DK570075A (da) 1970-02-24 1975-12-15 Benzylimidazolidinoner

Family Applications Before (1)

Application Number Title Priority Date Filing Date
DK83171AA DK134601B (da) 1970-02-24 1971-02-24 Analogifremgangsmåde til fremstilling af benzylimidazolidioner.

Country Status (18)

Country Link
US (1) US3636039A (da)
JP (1) JPS5421338B1 (da)
BE (1) BE763298A (da)
BR (1) BR7101125D0 (da)
CA (1) CA967163A (da)
CH (2) CH567483A5 (da)
DE (1) DE2108438C2 (da)
DK (2) DK134601B (da)
FI (1) FI54919C (da)
FR (1) FR2081537B1 (da)
GB (1) GB1292768A (da)
IE (1) IE35283B1 (da)
IL (1) IL36237A (da)
NL (1) NL171446C (da)
NO (1) NO130680C (da)
SE (1) SE369190B (da)
YU (1) YU34407B (da)
ZA (1) ZA711077B (da)

Families Citing this family (32)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3932452A (en) * 1975-02-07 1976-01-13 Morton-Norwich Products, Inc. 1-Arylmethyl-2-imidazolidinones
US3966758A (en) * 1975-06-16 1976-06-29 Morton-Norwich Products, Inc. Anti-inflammatory 1-(substituted benzyl)-2-imidazolidinones
US4063022A (en) * 1976-11-22 1977-12-13 Morton-Norwich Products, Inc. Antisecretory 2-imidazolidinones
HU179019B (en) * 1978-11-01 1982-08-28 Gyogyszekutato Intezet Process for preparing 4-//3,4-dialkoxy-phenyl/-alkyl/- 2imidazolidinone derivatives
CA1188616A (en) * 1981-06-11 1985-06-11 Hoffmann-La Roche Limited Pharmaceutical preparations
US5459145A (en) * 1988-01-19 1995-10-17 Pfizer Inc. Calcium independent camp phosphodiesterase inhibitor antidepressant
HU215433B (hu) * 1986-04-29 2000-05-28 Pfizer Inc. Eljárás új 2-oxo-5-fenil-pirimidin-származékok előállítására
US5395935A (en) * 1992-05-08 1995-03-07 Pfizer Inc. Endo-bicyclo[2.2.1]heptan-2-ol and derived pharmaceutical agents
GB9312853D0 (en) * 1993-06-22 1993-08-04 Euro Celtique Sa Chemical compounds
US5922751A (en) * 1994-06-24 1999-07-13 Euro-Celtique, S.A. Aryl pyrazole compound for inhibiting phosphodiesterase IV and methods of using same
US5591776A (en) * 1994-06-24 1997-01-07 Euro-Celtique, S.A. Pheynl or benzyl-substituted rolipram-based compounds for and method of inhibiting phosphodiesterase IV
WO1996018399A1 (en) * 1994-12-13 1996-06-20 Euro-Celtique, S.A. Aryl thioxanthines
US6025361A (en) * 1994-12-13 2000-02-15 Euro-Celtique, S.A. Trisubstituted thioxanthines
AU4527996A (en) * 1994-12-13 1996-07-03 Euro-Celtique S.A. Trisubstituted thioxanthines
US6166041A (en) * 1995-10-11 2000-12-26 Euro-Celtique, S.A. 2-heteroaryl and 2-heterocyclic benzoxazoles as PDE IV inhibitors for the treatment of asthma
US6075016A (en) * 1996-04-10 2000-06-13 Euro-Celtique S.A. 6,5-fused aromatic ring systems having enhanced phosphodiesterase IV inhibitory activity
US5864037A (en) 1996-06-06 1999-01-26 Euro-Celtique, S.A. Methods for the synthesis of chemical compounds having PDE-IV inhibitory activity
US5744473A (en) * 1996-09-16 1998-04-28 Euro-Celtique, S.A. PDE IV inhibitors: "bis-compounds"
EP2258689A1 (en) 2000-03-16 2010-12-08 Biolipox AB Benzylated PDE4 inhibitors
US7772188B2 (en) 2003-01-28 2010-08-10 Ironwood Pharmaceuticals, Inc. Methods and compositions for the treatment of gastrointestinal disorders
MX354786B (es) 2007-06-04 2018-03-21 Synergy Pharmaceuticals Inc Agonistas de guanilato ciclasa utiles para el tratamiento de trastornos gastrointestinales, inflamacion, cancer y otros trastornos.
US8969514B2 (en) 2007-06-04 2015-03-03 Synergy Pharmaceuticals, Inc. Agonists of guanylate cyclase useful for the treatment of hypercholesterolemia, atherosclerosis, coronary heart disease, gallstone, obesity and other cardiovascular diseases
CA2726917C (en) 2008-06-04 2018-06-26 Synergy Pharmaceuticals Inc. Agonists of guanylate cyclase useful for the treatment of gastrointestinal disorders, inflammation, cancer and other disorders
WO2010009319A2 (en) 2008-07-16 2010-01-21 Synergy Pharmaceuticals Inc. Agonists of guanylate cyclase useful for the treatment of gastrointestinal, inflammation, cancer and other disorders
US9616097B2 (en) 2010-09-15 2017-04-11 Synergy Pharmaceuticals, Inc. Formulations of guanylate cyclase C agonists and methods of use
US9580471B2 (en) 2011-03-01 2017-02-28 Synergy Pharmaceuticals, Inc. Process of preparing guanylate cyclase C agonists
US9545446B2 (en) 2013-02-25 2017-01-17 Synergy Pharmaceuticals, Inc. Agonists of guanylate cyclase and their uses
EP2970384A1 (en) 2013-03-15 2016-01-20 Synergy Pharmaceuticals Inc. Agonists of guanylate cyclase and their uses
WO2014151200A2 (en) 2013-03-15 2014-09-25 Synergy Pharmaceuticals Inc. Compositions useful for the treatment of gastrointestinal disorders
JP6606491B2 (ja) 2013-06-05 2019-11-13 シナジー ファーマシューティカルズ インコーポレイテッド グアニル酸シクラーゼｃの超高純度アゴニスト、その作成および使用方法
JP6694385B2 (ja) 2013-08-09 2020-05-13 アーデリクス，インコーポレーテッド リン酸塩輸送阻害のための化合物及び方法
WO2020237096A1 (en) 2019-05-21 2020-11-26 Ardelyx, Inc. Combination for lowering serum phosphate in a patient

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH518285A (de) * 1968-05-01 1972-01-31 Hoffmann La Roche Verfahren zur Herstellung von neuen substituierten Benzylimidazolidinonen

Also Published As

Publication number Publication date
IL36237A (en) 1974-11-29
NL171446C (nl) 1983-04-05
IL36237A0 (en) 1971-04-28
DK134601C (da) 1977-05-16
SE369190B (da) 1974-08-12
NL7102324A (da) 1971-08-26
FI54919B (fi) 1978-12-29
FR2081537B1 (da) 1974-08-23
BR7101125D0 (pt) 1973-04-26
DK134601B (da) 1976-12-06
US3636039A (en) 1972-01-18
NL171446B (nl) 1982-11-01
BE763298A (fr) 1971-08-23
YU34407B (en) 1979-07-10
FI54919C (fi) 1979-04-10
ZA711077B (en) 1971-10-27
DE2108438A1 (de) 1971-09-09
YU43971A (en) 1978-12-31
DE2108438C2 (de) 1987-02-05
IE35283B1 (en) 1976-01-07
NO130680C (da) 1975-01-22
JPS5421338B1 (da) 1979-07-30
GB1292768A (en) 1972-10-11
FR2081537A1 (da) 1971-12-03
CH567482A5 (da) 1975-10-15
NO130680B (da) 1974-10-14
CH567483A5 (da) 1975-10-15
CA967163A (en) 1975-05-06
IE35283L (en) 1971-08-24

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