FI52579C - Analogous process for the preparation of therapeutically active alpha- (4-piperidino) -aliphatic carbonic acid compounds. - Google Patents

Analogous process for the preparation of therapeutically active alpha- (4-piperidino) -aliphatic carbonic acid compounds.

Info

Publication number
FI52579C
FI52579C FI690885A FI88569A FI52579C FI 52579 C FI52579 C FI 52579C FI 690885 A FI690885 A FI 690885A FI 88569 A FI88569 A FI 88569A FI 52579 C FI52579 C FI 52579C
Authority
FI
Finland
Prior art keywords
piperidino
preparation
carbonic acid
therapeutically active
acid compounds
Prior art date
Application number
FI690885A
Other languages
Finnish (fi)
Swedish (sv)
Other versions
FI52579B (en
Inventor
Richard William James Carney
George De Stevens
Original Assignee
Ciba Geigy Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ciba Geigy Ag filed Critical Ciba Geigy Ag
Publication of FI52579B publication Critical patent/FI52579B/fi
Application granted granted Critical
Publication of FI52579C publication Critical patent/FI52579C/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/18—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D207/22—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/24—Oxygen or sulfur atoms
    • C07D207/26—2-Pyrrolidones
    • C07D207/263—2-Pyrrolidones with only hydrogen atoms or radicals containing only hydrogen and carbon atoms directly attached to other ring carbon atoms
    • C07D207/27—2-Pyrrolidones with only hydrogen atoms or radicals containing only hydrogen and carbon atoms directly attached to other ring carbon atoms with substituted hydrocarbon radicals directly attached to the ring nitrogen atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C205/00—Compounds containing nitro groups bound to a carbon skeleton
    • C07C205/49—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by carboxyl groups
    • C07C205/56—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by carboxyl groups having nitro groups bound to carbon atoms of six-membered aromatic rings and carboxyl groups bound to acyclic carbon atoms of the carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/18—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D207/20—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D207/34—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/36—Oxygen or sulfur atoms
    • C07D207/40—2,5-Pyrrolidine-diones
    • C07D207/404—2,5-Pyrrolidine-diones with only hydrogen atoms or radicals containing only hydrogen and carbon atoms directly attached to other ring carbon atoms, e.g. succinimide
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/44—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having three double bonds between ring members or between ring members and non-ring members
    • C07D207/444—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having three double bonds between ring members or between ring members and non-ring members having two doubly-bound oxygen atoms directly attached in positions 2 and 5
    • C07D207/448—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having three double bonds between ring members or between ring members and non-ring members having two doubly-bound oxygen atoms directly attached in positions 2 and 5 with only hydrogen atoms or radicals containing only hydrogen and carbon atoms directly attached to other ring carbon atoms, e.g. maleimide
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/46—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with hetero atoms directly attached to the ring nitrogen atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/44—Iso-indoles; Hydrogenated iso-indoles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/44—Iso-indoles; Hydrogenated iso-indoles
    • C07D209/46—Iso-indoles; Hydrogenated iso-indoles with an oxygen atom in position 1
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/44—Iso-indoles; Hydrogenated iso-indoles
    • C07D209/48—Iso-indoles; Hydrogenated iso-indoles with oxygen atoms in positions 1 and 3, e.g. phthalimide
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D211/40—Oxygen atoms
    • C07D211/42—Oxygen atoms attached in position 3 or 5
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D211/40—Oxygen atoms
    • C07D211/44—Oxygen atoms attached in position 4
    • C07D211/46—Oxygen atoms attached in position 4 having a hydrogen atom as the second substituent in position 4
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/68—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D211/72—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D211/78—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/54—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/55—Acids; Esters
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
    • C07D217/22—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the nitrogen-containing ring
    • C07D217/24—Oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/16—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
    • C07D295/18—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carboxylic acids, or sulfur or nitrogen analogues thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/16—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
    • C07D295/18—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carboxylic acids, or sulfur or nitrogen analogues thereof
    • C07D295/182—Radicals derived from carboxylic acids
    • C07D295/185—Radicals derived from carboxylic acids from aliphatic carboxylic acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/34—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D307/56—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D307/66—Nitrogen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pain & Pain Management (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Rheumatology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Hydrogenated Pyridines (AREA)
  • Pyrrole Compounds (AREA)
FI690885A 1968-03-27 1969-03-26 Analogous process for the preparation of therapeutically active alpha- (4-piperidino) -aliphatic carbonic acid compounds. FI52579C (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US71634768A 1968-03-27 1968-03-27
US75713668A 1968-09-03 1968-09-03
US79086369A 1969-01-13 1969-01-13

Publications (2)

Publication Number Publication Date
FI52579B FI52579B (en) 1977-06-30
FI52579C true FI52579C (en) 1977-10-10

Family

ID=27418953

Family Applications (1)

Application Number Title Priority Date Filing Date
FI690885A FI52579C (en) 1968-03-27 1969-03-26 Analogous process for the preparation of therapeutically active alpha- (4-piperidino) -aliphatic carbonic acid compounds.

Country Status (26)

Country Link
JP (1) JPS5330712B1 (en)
AR (7) AR192864A1 (en)
AT (8) AT287685B (en)
BE (1) BE730520A (en)
BG (3) BG20567A3 (en)
CH (11) CH563985A5 (en)
CS (8) CS153503B2 (en)
CY (1) CY809A (en)
DE (1) DE1913743A1 (en)
DK (1) DK145226C (en)
FI (1) FI52579C (en)
FR (1) FR2004827A1 (en)
GB (1) GB1268831A (en)
IE (1) IE33153B1 (en)
IL (1) IL31861A (en)
KE (1) KE2542A (en)
MY (1) MY7500152A (en)
NL (1) NL162647C (en)
NO (1) NO132199C (en)
OA (1) OA03609A (en)
PH (1) PH12640A (en)
PL (1) PL74820B1 (en)
RO (4) RO66273A (en)
SE (1) SE382812B (en)
SU (4) SU428600A3 (en)
YU (3) YU39653B (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2025518A1 (en) * 1969-06-05 1970-12-10
DE2013376A1 (en) * 1970-03-20 1971-10-07 Merck Patent Gmbh Substituted phenylacetic acids and processes for their preparation

Also Published As

Publication number Publication date
DE1913743A1 (en) 1969-11-20
YU39926B (en) 1985-06-30
CH563983A5 (en) 1975-07-15
CY809A (en) 1976-12-01
CH566991A5 (en) 1975-09-30
FI52579B (en) 1977-06-30
AT291237B (en) 1971-07-12
YU39653B (en) 1985-03-20
SU428600A3 (en) 1974-05-15
AT291242B (en) 1971-07-12
CS153508B2 (en) 1974-02-25
RO66273A (en) 1981-08-17
BG20340A3 (en) 1975-11-05
AT291240B (en) 1971-07-12
FR2004827A1 (en) 1969-12-05
AR194569A1 (en) 1973-07-31
BG20567A3 (en) 1975-12-05
CS153511B2 (en) 1974-02-25
SU459886A3 (en) 1975-02-05
CH563989A5 (en) 1975-07-15
YU149975A (en) 1982-06-30
AT291234B (en) 1971-07-12
YU200174A (en) 1982-06-30
IE33153B1 (en) 1974-04-03
CH559755A5 (en) 1975-03-14
AR193025A1 (en) 1973-03-30
CH554859A (en) 1974-10-15
RO66269A (en) 1979-03-15
YU200074A (en) 1982-06-30
CS153510B2 (en) 1974-02-25
YU39532B (en) 1984-12-31
CH563381A5 (en) 1975-06-30
AR193194A1 (en) 1973-04-11
NL162647B (en) 1980-01-15
IE33153L (en) 1969-09-27
CH563988A5 (en) 1975-07-15
NL6903273A (en) 1969-09-30
AR193024A1 (en) 1973-03-30
BE730520A (en) 1969-09-26
DK145226C (en) 1983-03-28
CS153505B2 (en) 1974-02-25
IL31861A (en) 1974-03-14
AR192560A1 (en) 1973-02-28
GB1268831A (en) 1972-03-29
MY7500152A (en) 1975-12-31
CS153504B2 (en) 1974-02-25
CS153506B2 (en) 1974-02-25
RO64901A (en) 1979-08-15
AR192699A1 (en) 1973-03-14
DK145226B (en) 1982-10-11
NL162647C (en) 1980-06-16
JPS5330712B1 (en) 1978-08-29
IL31861A0 (en) 1969-05-28
CH563984A5 (en) 1975-07-15
AR192864A1 (en) 1973-03-21
AT291235B (en) 1971-07-12
BG20339A3 (en) 1975-11-05
NO132199B (en) 1975-06-23
SU419029A3 (en) 1974-03-05
AT287685B (en) 1971-02-10
SU421191A3 (en) 1974-03-25
CS153503B2 (en) 1974-02-25
OA03609A (en) 1971-03-30
SE382812B (en) 1976-02-16
RO61382A (en) 1976-10-15
CH563986A5 (en) 1975-07-15
AT291241B (en) 1971-07-12
PL74820B1 (en) 1974-12-31
CH566990A5 (en) 1975-09-30
AT291239B (en) 1971-07-12
CS153502B2 (en) 1974-02-25
PH12640A (en) 1979-07-05
NO132199C (en) 1975-10-08
KE2542A (en) 1975-07-25
CH563985A5 (en) 1975-07-15

Similar Documents

Publication Publication Date Title
FI49035C (en) Process for the preparation of therapeutically useful 2-bromo-alpha-gocryptine.
FI48590C (en) Process for the preparation of therapeutically useful azaspiroalkandion compounds.
FI52858C (en) Process for the preparation of therapeutically active 1- (beta-aryl) ethylimidazole derivatives.
FI51046C (en) Process for the preparation of acetocalicylic acid tablet.
FI48062C (en) Process for the preparation of xylitol
DK123605B (en) Process for the preparation of antibiotically active bleomycins.
FI49512C (en) Process for the preparation of novel therapeutically active s-triazinyl-piperazine derivatives.
FI50334C (en) Process for the preparation of 1-hydroxy-2-pyridones.
FI47365C (en) Process for the preparation of new therapeutically active indolder t.
FI47575C (en) Analogous process for the preparation of evomonoside derivatives.
FI49827C (en) Process for the preparation of therapeutically active substituted 3-hydroxymethylisoquinolines.
FI51484C (en) Process for the preparation of 7beta- (D-5-amino-5-carboxy-valeramido) -3- (carbamoyloxymethyl) -7-methoxy-3-cephem-4-carboxylic acid antibiotic.
FI52586C (en) Process for the preparation of therapeutically active cephalosporins ivat
FI52579C (en) Analogous process for the preparation of therapeutically active alpha- (4-piperidino) -aliphatic carbonic acid compounds.
FI49032C (en) Process for the preparation of therapeutically active 7-nitro-8-hydroxyquinoline esters.
FI51183C (en) Process for the preparation of 2-hydroxymethyl-3-carboxylic acid amido-quinoxaline-di-N-oxide (1,4) compounds.
FI50407C (en) Process for the preparation of trichloromonosilanes
NO741044L (en) Analogous process for the preparation of therapeutically active triazines.
FI52577C (en) Process for the preparation of therapeutically useful phenazine derivatives.
FI47189C (en) Process for the preparation of therapeutically active d-lysergic acid-N-phenylpiperazides.
FI50875C (en) Process for the preparation of therapeutically active dihydro-2-aminoisoquinolines.
FI50243C (en) Process for the preparation of therapeutically active N-substituted 3-hydroxy-9-azamorfinan.
FI45045C (en) Process for the preparation of novel therapeutically active 5-nitro-2-furyl-isoxazole derivatives.
FI52088C (en) Process for the preparation of 3- (4-acyloxyalkyl-1-piperazinyl) -carbonylmethyl-2-benzothiazolinone derivatives.
FI47101C (en) Process for the preparation of therapeutically active alpha- (3-indolyl) -lower aliphatic acids.