FI50333C - Method for preparing therapeutically active levo-1-n-butyl-2 ', 6'-pipecoloxy lidide. - Google Patents

Method for preparing therapeutically active levo-1-n-butyl-2 ', 6'-pipecoloxy lidide.

Info

Publication number
FI50333C
FI50333C FI681394A FI139468A FI50333C FI 50333 C FI50333 C FI 50333C FI 681394 A FI681394 A FI 681394A FI 139468 A FI139468 A FI 139468A FI 50333 C FI50333 C FI 50333C
Authority
FI
Finland
Prior art keywords
pipecoloxy
lidide
butyl
therapeutically active
preparing therapeutically
Prior art date
Application number
FI681394A
Other languages
Finnish (fi)
Swedish (sv)
Other versions
FI50333B (en
Inventor
Froilan Pindaro Luduena
Benjamin Franklin Tullar
Original Assignee
Sterling Drug Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sterling Drug Inc filed Critical Sterling Drug Inc
Application granted granted Critical
Publication of FI50333B publication Critical patent/FI50333B/fi
Publication of FI50333C publication Critical patent/FI50333C/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D211/60—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
FI681394A 1967-05-18 1968-05-17 Method for preparing therapeutically active levo-1-n-butyl-2 ', 6'-pipecoloxy lidide. FI50333C (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US63927767A 1967-05-18 1967-05-18

Publications (2)

Publication Number Publication Date
FI50333B FI50333B (en) 1975-10-31
FI50333C true FI50333C (en) 1976-02-10

Family

ID=24563449

Family Applications (1)

Application Number Title Priority Date Filing Date
FI681394A FI50333C (en) 1967-05-18 1968-05-17 Method for preparing therapeutically active levo-1-n-butyl-2 ', 6'-pipecoloxy lidide.

Country Status (13)

Country Link
AT (2) AT284843B (en)
BE (1) BE715188A (en)
CH (1) CH498834A (en)
DE (1) DE1770408C3 (en)
DK (1) DK129234B (en)
ES (1) ES354352A1 (en)
FI (1) FI50333C (en)
FR (2) FR1583872A (en)
GB (1) GB1180712A (en)
IL (1) IL29958A (en)
NL (1) NL6806995A (en)
NO (1) NO124540B (en)
SE (1) SE341404B (en)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3379266D1 (en) * 1983-08-01 1989-04-06 Astra Laekemedel Ab L-n-n-propylpipecolic acid-2,6-xylidide and method for preparing the same
SE451840B (en) * 1986-01-03 1987-11-02 Astra Laekemedel Ab OPTICALLY PURE MONOHYDRATED OF S - (-) - 1-PROPYL-2 ', 6'-PIPECOLOXYLIDE HYDROCHLORIDE, SET TO PREPARE THIS AND PHARMACEUTICAL PREPARATIONS FOR LOCAL ANCHORING
US5994548A (en) * 1994-10-25 1999-11-30 Darwin Discovery Ltd. Crystallisation of levibupivacaine and analogues thereof
SE9501808D0 (en) * 1995-05-16 1995-05-16 Astra Ab New process
KR100844336B1 (en) * 2007-01-16 2008-07-07 하나제약 주식회사 New synthetic method of levobupivacaine and its hydrochloride
WO2014009964A1 (en) * 2012-07-11 2014-01-16 Neon Laboratories Limited Process for enantiomeric enrichment of 2 ', 6 ' - pipecoloxylidide
CN105315196A (en) * 2015-11-28 2016-02-10 山东齐都药业有限公司 High-purity levobupivacaine hydrochloride refining method
CN109896992A (en) * 2017-12-08 2019-06-18 武汉软件工程职业学院 Prepare the method and its application of ionic liquid

Also Published As

Publication number Publication date
DE1770408B2 (en) 1974-04-11
AT284843B (en) 1970-09-25
DK129234B (en) 1974-09-16
AT286298B (en) 1970-12-10
GB1180712A (en) 1970-02-11
FR1583872A (en) 1969-12-05
DE1770408A1 (en) 1971-10-21
IL29958A (en) 1971-04-28
DK129234C (en) 1975-02-03
SE341404B (en) 1971-12-27
DE1770408C3 (en) 1974-11-07
ES354352A1 (en) 1969-11-01
NL6806995A (en) 1968-11-19
BE715188A (en) 1968-09-30
CH498834A (en) 1970-11-15
NO124540B (en) 1972-05-02
IL29958A0 (en) 1968-07-25
FR8160M (en) 1970-08-24
FI50333B (en) 1975-10-31

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