AT284843B - Process for the preparation of the new laevo-1-n-butyl-2 ', 6'-pipecoloxylidids and its salts - Google Patents

Process for the preparation of the new laevo-1-n-butyl-2 ', 6'-pipecoloxylidids and its salts

Info

Publication number
AT284843B
AT284843B AT475368A AT475368A AT284843B AT 284843 B AT284843 B AT 284843B AT 475368 A AT475368 A AT 475368A AT 475368 A AT475368 A AT 475368A AT 284843 B AT284843 B AT 284843B
Authority
AT
Austria
Prior art keywords
pipecoloxylidids
laevo
butyl
salts
preparation
Prior art date
Application number
AT475368A
Other languages
German (de)
Original Assignee
Sterling Drug Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sterling Drug Inc filed Critical Sterling Drug Inc
Application granted granted Critical
Publication of AT284843B publication Critical patent/AT284843B/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D211/60—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
AT475368A 1967-05-18 1968-05-17 Process for the preparation of the new laevo-1-n-butyl-2 ', 6'-pipecoloxylidids and its salts AT284843B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US63927767A 1967-05-18 1967-05-18

Publications (1)

Publication Number Publication Date
AT284843B true AT284843B (en) 1970-09-25

Family

ID=24563449

Family Applications (2)

Application Number Title Priority Date Filing Date
AT475368A AT284843B (en) 1967-05-18 1968-05-17 Process for the preparation of the new laevo-1-n-butyl-2 ', 6'-pipecoloxylidids and its salts
AT1097469A AT286298B (en) 1967-05-18 1968-05-17 Process for the preparation of the new laevo-1-n-butyl-2 ', 6'-pipecoloxylidids and its salts

Family Applications After (1)

Application Number Title Priority Date Filing Date
AT1097469A AT286298B (en) 1967-05-18 1968-05-17 Process for the preparation of the new laevo-1-n-butyl-2 ', 6'-pipecoloxylidids and its salts

Country Status (13)

Country Link
AT (2) AT284843B (en)
BE (1) BE715188A (en)
CH (1) CH498834A (en)
DE (1) DE1770408C3 (en)
DK (1) DK129234B (en)
ES (1) ES354352A1 (en)
FI (1) FI50333C (en)
FR (2) FR1583872A (en)
GB (1) GB1180712A (en)
IL (1) IL29958A (en)
NL (1) NL6806995A (en)
NO (1) NO124540B (en)
SE (1) SE341404B (en)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE40994T1 (en) * 1983-08-01 1989-03-15 Astra Laekemedel Ab L-N-N-PROPYLPIPECOLIC-2,6-XYLIDIDE AND ITS PRODUCTION.
SE451840B (en) * 1986-01-03 1987-11-02 Astra Laekemedel Ab OPTICALLY PURE MONOHYDRATED OF S - (-) - 1-PROPYL-2 ', 6'-PIPECOLOXYLIDE HYDROCHLORIDE, SET TO PREPARE THIS AND PHARMACEUTICAL PREPARATIONS FOR LOCAL ANCHORING
DK0788480T3 (en) * 1994-10-25 2003-09-29 Darwin Discovery Ltd Crystallization of levobupivacaine and analogues thereof
SE9501808D0 (en) * 1995-05-16 1995-05-16 Astra Ab New process
KR100844336B1 (en) * 2007-01-16 2008-07-07 하나제약 주식회사 New synthetic method of levobupivacaine and its hydrochloride
WO2014009964A1 (en) * 2012-07-11 2014-01-16 Neon Laboratories Limited Process for enantiomeric enrichment of 2 ', 6 ' - pipecoloxylidide
CN105315196A (en) * 2015-11-28 2016-02-10 山东齐都药业有限公司 High-purity levobupivacaine hydrochloride refining method
CN109896992A (en) * 2017-12-08 2019-06-18 武汉软件工程职业学院 Prepare the method and its application of ionic liquid

Also Published As

Publication number Publication date
GB1180712A (en) 1970-02-11
DE1770408B2 (en) 1974-04-11
FI50333B (en) 1975-10-31
NO124540B (en) 1972-05-02
NL6806995A (en) 1968-11-19
DK129234B (en) 1974-09-16
DE1770408A1 (en) 1971-10-21
FR1583872A (en) 1969-12-05
BE715188A (en) 1968-09-30
SE341404B (en) 1971-12-27
IL29958A (en) 1971-04-28
FI50333C (en) 1976-02-10
DK129234C (en) 1975-02-03
ES354352A1 (en) 1969-11-01
AT286298B (en) 1970-12-10
IL29958A0 (en) 1968-07-25
DE1770408C3 (en) 1974-11-07
CH498834A (en) 1970-11-15
FR8160M (en) 1970-08-24

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