FI49715C - Menetelmä bakteerienvastaisten 2,4-diamino-5-bentsyylipyrimidiinien va lmistamiseksi. - Google Patents

Menetelmä bakteerienvastaisten 2,4-diamino-5-bentsyylipyrimidiinien va lmistamiseksi.

Info

Publication number
FI49715C
FI49715C FI182766A FI182766A FI49715C FI 49715 C FI49715 C FI 49715C FI 182766 A FI182766 A FI 182766A FI 182766 A FI182766 A FI 182766A FI 49715 C FI49715 C FI 49715C
Authority
FI
Finland
Prior art keywords
benzylpyrimidines
diamino
antibacterial
preparation
Prior art date
Application number
FI182766A
Other languages
English (en)
Finnish (fi)
Swedish (sv)
Other versions
FI49715B (it
Inventor
Ronald Morton Cresswell
John William Mentha
Bernard Stuart Hurlbert
Original Assignee
Wellcome Found
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wellcome Found filed Critical Wellcome Found
Priority to FI281169A priority Critical patent/FI49154C/fi
Application granted granted Critical
Publication of FI49715B publication Critical patent/FI49715B/fi
Publication of FI49715C publication Critical patent/FI49715C/fi

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/48—Two nitrogen atoms
    • C07D239/49—Two nitrogen atoms with an aralkyl radical, or substituted aralkyl radical, attached in position 5, e.g. trimethoprim
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00—Carboxylic acid nitriles

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
FI182766A 1965-07-08 1966-07-07 Menetelmä bakteerienvastaisten 2,4-diamino-5-bentsyylipyrimidiinien va lmistamiseksi. FI49715C (fi)

Priority Applications (1)

Application Number Priority Date Filing Date Title
FI281169A FI49154C (fi) 1965-07-08 1969-09-30 Uudet hydrokinnamonitriilijohdannaiset, jotka ovat välituotteita biolo gisesti aktiivisten 2,4-diamino-5-bentsyylipyrimidiinien valmistamises sa, ja menetelmä niiden valmistamiseksi.

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US47060665A 1965-07-08 1965-07-08

Publications (2)

Publication Number Publication Date
FI49715B FI49715B (it) 1975-06-02
FI49715C true FI49715C (fi) 1975-09-10

Family

ID=23868272

Family Applications (1)

Application Number Title Priority Date Filing Date
FI182766A FI49715C (fi) 1965-07-08 1966-07-07 Menetelmä bakteerienvastaisten 2,4-diamino-5-bentsyylipyrimidiinien va lmistamiseksi.

Country Status (6)

Country Link
BE (1) BE683875A (it)
BR (1) BR6681138D0 (it)
DE (1) DE1620729A1 (it)
FI (1) FI49715C (it)
IT (1) IT1062274B (it)
NL (1) NL6609626A (it)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2065367C2 (de) * 1969-03-06 1985-04-04 The Wellcome Foundation Ltd., London Verfahren zur Herstellung von 2,4- Diamino-5-benzylpyrimidinen
GB1261455A (en) * 1969-03-06 1972-01-26 Burroughs Wellcome Co Improvements in or relating to substituted acrylonitriles
BR6915082D0 (pt) 1969-05-16 1973-03-08 Wellcome Found Processo de preparacao de benzil-pirimidinas
DE2051871A1 (en) * 1969-05-16 1971-11-18 The Wellcome Foundation Ltd., London Beta-amino-alpha-aryloxymethylacrylonitrile - and 2,4-diamino-5-benzylpyrimidine derivs. useful as antibacterial agents
BE792096A (fr) * 1971-12-01 1973-05-30 Hoffmann La Roche Nouvelles benzylpyrimidines
BE795023A (fr) * 1972-02-07 1973-08-06 Hoffmann La Roche Nouvelles benzylpyrimidines
EP0046856A3 (de) * 1980-08-29 1982-07-28 Hüls Troisdorf Aktiengesellschaft Verfahren zur Herstellung von 4-Amino-2-mercaptopyrimidinen
DE4333688C2 (de) * 1993-10-02 2003-11-06 Guenter Ege Verfahren zur Herstellung von 3-Aryl-2-(dialkoxymethyl)-propannitrilen und ihre Umsetzung zu 5-Arylmethyl-2,4-diamino-pyrimidinen, insbesondere zu Trimethoprim
CN107162989A (zh) * 2017-05-27 2017-09-15 山东新华制药股份有限公司 一种甲氧苄啶杂质的制备方法

Also Published As

Publication number Publication date
IT1062274B (it) 1984-02-29
NL6609626A (it) 1967-01-09
BE683875A (it) 1967-01-09
DE1620729A1 (de) 1970-08-20
FI49715B (it) 1975-06-02
BR6681138D0 (pt) 1973-12-26

Similar Documents

Publication Publication Date Title
FI49716C (fi) Menetelmä 2,4-diamino-5-bentsyyli-pyrimidiinien valmistamiseksi.
FI45966C (fi) Menetelmä kokkiostaattisesti aktiivisten 4-hydroksi-6,7-dialkoksi-3-ka rboalkoksikinoliinien valmistamiseksi.
DK112523B (da) Fremgangsmåde til fremstilling af 2,3-pyridindiol.
FI49715C (fi) Menetelmä bakteerienvastaisten 2,4-diamino-5-bentsyylipyrimidiinien va lmistamiseksi.
FI52090C (fi) Menetelmä mikrobeja tappavan 2-amino-4-hydroksi-7,7-dimetyyli-7,8-dihy dropteridiinin valmistamiseksi
FI47577C (fi) Tapa valmistaa sepelvaltimoita laajentavan vaikutuksen omaavia 2,4,7-t riamino-6-fenyyli-pteridiinejä.
DK115184B (da) Fremgangsmåde til fremstilling af 6,7-benzomorphaner.
FI52862C (fi) Menetelmä uusien mikrobinvastaisten 3-(5-nitro-2-imidatsolyyli-metylee ni-amino)-2-oksatsolidinonien valmistamiseksi.
FI45655C (fi) Menetelmä alfa-metyyli-alfa-amino-beta-(3,4-disubstituoitu-fenyyli)pro pionitriilien valmistamiseksi.
DK123169B (da) Fremgangsmåde til fremstilling af 2,5-dichlor-4-alkylmercaptophenoler.
DK120347B (da) Fremgangsmåde til fremstilling af 1,4-benzodiazepin-4-oxider.
DK116357B (da) Fremgangsmåde til fremstilling af 1,1,1,2,2-pentafluor-3-chlorpropan.
FI50710C (fi) Menetelmä 1,4-bentsodiatsepiinien valmistamiseksi.
DK116594B (da) Fremgangsmåde til fremstilling af 4,1,5-benzoxadiazociner.
DK114962B (da) Fremgangsmåde til fremstilling af α, α, α', α'-tetramethyl-xylylen-dicarbinoler.
DK115622B (da) Fremgangsmåde til fremstilling af 3-oxogona-4,9,11-triener.
DK120131B (da) Fremgangsmåde til fremstilling af 3-oxo-13β-alkylgona-4,9,11-triener.
FI46723C (fi) Menetelmä 1,18-dimetyyli-5alfa-H-androst-1-eenijohdannaisten valmistam iseksi.
FI45755C (fi) Menetelmä 1,2-epoksi-9beta,10alfa-steroidien valmistamiseksi.
NL139736B (nl) Werkwijze voor de bereiding van 2,2,6,6-tetrachloorcyclohexanon.
FI45324C (fi) Menetelmä 17beta-(1-alkoksi-sykloalkyyli)oksi-2alfa,3alfa-epitio-5alfa -androstaanien valmistamiseksi.
FI47759C (fi) Menetelmä uusien tetrakosapeptidien valmistamiseksi, joilla on ACTH-te ho.
DK120813B (da) Fremgangsmåde til fremstilling af antibiotiket 17.967 RP.
DK118947B (da) Fremgangsmåde til fremstilling af 1,2-dihydro-4-hydroxyquinazolin-3-oxider.
FI49830C (fi) Menetelmä bakteerienvastaisten 2-amino-3-karbamoyylikinoksaliini-di-N- oksidien valmistamiseksi.