FI3229776T3 - Farmaseuttinen koostumus, joka yhdistää ainakin kaksi erillistä nanopartikkelia ja farmaseuttisen yhdisteen, sen valmistus ja käytöt - Google Patents
Farmaseuttinen koostumus, joka yhdistää ainakin kaksi erillistä nanopartikkelia ja farmaseuttisen yhdisteen, sen valmistus ja käytöt Download PDFInfo
- Publication number
- FI3229776T3 FI3229776T3 FIEP15800777.3T FI15800777T FI3229776T3 FI 3229776 T3 FI3229776 T3 FI 3229776T3 FI 15800777 T FI15800777 T FI 15800777T FI 3229776 T3 FI3229776 T3 FI 3229776T3
- Authority
- FI
- Finland
- Prior art keywords
- compound
- pharmaceutical
- pharmaceutical compound
- pharmaceutical composition
- biocompatible
- Prior art date
Links
- 150000001875 compounds Chemical class 0.000 title claims 24
- 239000002105 nanoparticle Substances 0.000 title claims 18
- 239000008194 pharmaceutical composition Substances 0.000 title claims 13
- 230000001225 therapeutic effect Effects 0.000 claims 8
- 230000001988 toxicity Effects 0.000 claims 6
- 231100000419 toxicity Toxicity 0.000 claims 6
- 231100000433 cytotoxic Toxicity 0.000 claims 2
- 230000001472 cytotoxic effect Effects 0.000 claims 2
- 238000002405 diagnostic procedure Methods 0.000 claims 2
- 230000000069 prophylactic effect Effects 0.000 claims 2
- 150000003384 small molecules Chemical class 0.000 claims 2
- 238000011287 therapeutic dose Methods 0.000 claims 2
- 229940126585 therapeutic drug Drugs 0.000 claims 2
- 108091034117 Oligonucleotide Proteins 0.000 claims 1
- 239000011248 coating agent Substances 0.000 claims 1
- 238000000576 coating method Methods 0.000 claims 1
- 150000002484 inorganic compounds Chemical class 0.000 claims 1
- 229910010272 inorganic material Inorganic materials 0.000 claims 1
- 150000002632 lipids Chemical class 0.000 claims 1
- 239000002082 metal nanoparticle Substances 0.000 claims 1
- 229910044991 metal oxide Inorganic materials 0.000 claims 1
- 150000004706 metal oxides Chemical class 0.000 claims 1
- 229910052976 metal sulfide Inorganic materials 0.000 claims 1
- 239000000203 mixture Substances 0.000 claims 1
- 244000309459 oncolytic virus Species 0.000 claims 1
- 150000002894 organic compounds Chemical class 0.000 claims 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7028—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages
- A61K31/7034—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin
- A61K31/704—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin attached to a condensed carbocyclic ring system, e.g. sennosides, thiocolchicosides, escin, daunorubicin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S977/00—Nanotechnology
- Y10S977/70—Nanostructure
- Y10S977/773—Nanoparticle, i.e. structure having three dimensions of 100 nm or less
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S977/00—Nanotechnology
- Y10S977/902—Specified use of nanostructure
- Y10S977/904—Specified use of nanostructure for medical, immunological, body treatment, or diagnosis
- Y10S977/906—Drug delivery
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S977/00—Nanotechnology
- Y10S977/902—Specified use of nanostructure
- Y10S977/904—Specified use of nanostructure for medical, immunological, body treatment, or diagnosis
- Y10S977/906—Drug delivery
- Y10S977/907—Liposome
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Dispersion Chemistry (AREA)
- Molecular Biology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Saccharide Compounds (AREA)
- Steroid Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP14306874 | 2014-11-25 | ||
| PCT/EP2015/077446 WO2016083343A1 (en) | 2014-11-25 | 2015-11-24 | Pharmaceutical composition combining at least two distinct nanoparticles and a pharmaceutical compound, preparation and uses thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| FI3229776T3 true FI3229776T3 (fi) | 2023-08-15 |
Family
ID=52013981
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FIEP15800777.3T FI3229776T3 (fi) | 2014-11-25 | 2015-11-24 | Farmaseuttinen koostumus, joka yhdistää ainakin kaksi erillistä nanopartikkelia ja farmaseuttisen yhdisteen, sen valmistus ja käytöt |
Country Status (13)
| Country | Link |
|---|---|
| US (2) | US10391058B2 (enExample) |
| EP (1) | EP3229776B1 (enExample) |
| JP (1) | JP6836510B2 (enExample) |
| AR (1) | AR102781A1 (enExample) |
| DK (1) | DK3229776T3 (enExample) |
| ES (1) | ES2951598T3 (enExample) |
| FI (1) | FI3229776T3 (enExample) |
| HU (1) | HUE062561T2 (enExample) |
| LT (1) | LT3229776T (enExample) |
| PL (1) | PL3229776T3 (enExample) |
| PT (1) | PT3229776T (enExample) |
| TW (1) | TW201628654A (enExample) |
| WO (1) | WO2016083343A1 (enExample) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| UA116380C2 (uk) | 2013-05-30 | 2018-03-12 | Нанобіотікс | Посилення терапевтичної або профілактичної ефективності фармацевтичної сполуки |
| WO2016083331A1 (en) | 2014-11-25 | 2016-06-02 | Nanobiotix | Pharmaceutical composition, preparation and uses thereof |
| JP6836510B2 (ja) * | 2014-11-25 | 2021-03-03 | キュラディグム・エスアエスＣｕｒａｄｉｇｍ Ｓａｓ | 少なくとも２つの異なるナノ粒子と医薬化合物とを組み合わせた医薬組成物、その調製及び使用 |
| HUE056175T2 (hu) | 2014-11-25 | 2022-01-28 | Curadigm Sas | Gyógyászati készítmények, elõállításuk és alkalmazásaik |
| TW201628656A (zh) * | 2014-11-25 | 2016-08-16 | 奈諾生技公司 | 醫藥組合物、其製備與用途 |
| US11096962B2 (en) | 2015-05-28 | 2021-08-24 | Nanobiotix | Nanoparticles for use as a therapeutic vaccine |
| CN115137822B (zh) * | 2022-06-13 | 2023-06-23 | 武汉大学中南医院 | 一种光热热电一体化的抗肿瘤植入体的制备方法 |
Family Cites Families (45)
| Publication number | Priority date | Publication date | Assignee | Title |
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| US4280918A (en) | 1980-03-10 | 1981-07-28 | International Business Machines Corporation | Magnetic particle dispersions |
| GB9509321D0 (en) | 1995-05-09 | 1995-06-28 | Zylepsis Ltd | Methods of and substances for inhibiting oxidative enzymes |
| WO1998017667A1 (en) | 1996-10-18 | 1998-04-30 | Wayne State University | 6',7'-dihydroxybergamottin, a cytochrome p450 ihnibitor in grapefruit juice |
| JPH10120597A (ja) | 1996-10-22 | 1998-05-12 | Eiken Chem Co Ltd | リンパ節高集積性コロイド粒子 |
| ATE253357T1 (de) | 1997-08-19 | 2003-11-15 | Warner Lambert Co | Bergamottin enthaltende zusammensetzungen zur erhöhung der oralen bioverfügbarkeit von pharmazeutika |
| US7311924B2 (en) * | 1999-04-01 | 2007-12-25 | Hana Biosciences, Inc. | Compositions and methods for treating cancer |
| DE60115044T2 (de) * | 2000-06-30 | 2006-08-03 | Inex Pharmaceuticals Corp., Burnaby | Liposomale antineoplastische arzneimittel und deren verwendungen |
| US8178123B2 (en) | 2001-08-29 | 2012-05-15 | Femina Pharma Incorporated | Method for augmentation of intraepithelial and systemic exposure of therapeutic agents having substrate activity for cytochrome P450 enzymes and membrane efflux systems following vaginal and oral cavity administration |
| US20050090732A1 (en) | 2003-10-28 | 2005-04-28 | Triton Biosystems, Inc. | Therapy via targeted delivery of nanoscale particles |
| JP5513708B2 (ja) | 2003-12-22 | 2014-06-04 | ブラッコ・シュイス・ソシエテ・アノニム | 造影イメージング用の気体封入マイクロベシクル・アセンブリー |
| US20080193372A1 (en) * | 2004-02-10 | 2008-08-14 | Barnes-Jewish Hospital | Efficacy and Safety of Targeted Particulate Agents with Decoy Systems |
| US20060264804A1 (en) | 2005-04-07 | 2006-11-23 | Yoram Karmon | Device and kit for delivery of encapsulated substances and methods of use thereof |
| US20070088414A1 (en) * | 2005-05-25 | 2007-04-19 | Campbell Robert L | Particulate formulations for intradermal delivery of biologically active agents |
| DE102005039579B4 (de) * | 2005-08-19 | 2022-06-30 | Magforce Ag | Verfahren zur Einschleusung von therapeutischen Substanzen in Zellen |
| EP2000150B1 (en) * | 2006-03-24 | 2016-07-13 | Toto Ltd. | Titanium oxide complex particle, dispersion solution of the particle, and process for production of the particle |
| JP2009536151A (ja) | 2006-03-30 | 2009-10-08 | 富士フイルム株式会社 | ナノ粒子 |
| EP1852107A1 (en) | 2006-04-19 | 2007-11-07 | Nanobiotix | Magnetic nanoparticles compositions and uses thereof |
| CA2649870C (en) | 2006-05-04 | 2014-07-29 | University Of South Australia | Drug release from nanoparticle-coated capsules |
| AU2008288917A1 (en) | 2007-08-21 | 2009-02-26 | Alza Corporation | Liposome compositions for in vivo administration of boronic acid compounds |
| FR2922106B1 (fr) | 2007-10-16 | 2011-07-01 | Univ Claude Bernard Lyon | Utilisation de nanoparticules a base de lanthanides comme agents radiosensibilisants. |
| WO2009081287A2 (en) | 2007-12-21 | 2009-07-02 | University Of Guelph | Polysaccharide nanoparticles |
| US9403789B2 (en) | 2008-02-21 | 2016-08-02 | Sequoia Pharmaceuticals, Inc. | Benzofuran-containing amino acid inhibitors of cytochrome P450 |
| WO2009142754A1 (en) | 2008-05-22 | 2009-11-26 | Goverment Of The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Dendritic conjugates and methods of use |
| EP2130553A1 (en) | 2008-06-05 | 2009-12-09 | Nanobiotix | Inorganic nanoparticles of high density to destroy cells in-vivo |
| WO2010048623A2 (en) | 2008-10-26 | 2010-04-29 | Board Of Regents, The University Of Texas Systems | Medical and imaging nanoclusters |
| GB0921596D0 (en) | 2009-12-09 | 2010-01-27 | Isis Innovation | Particles for the treatment of cancer in combination with radiotherapy |
| JP5649137B2 (ja) | 2010-02-17 | 2015-01-07 | 国立大学法人神戸大学 | 放射線治療剤 |
| CN104784121A (zh) | 2010-03-26 | 2015-07-22 | 阿布拉科斯生物科学有限公司 | 治疗肝细胞癌的方法 |
| GB201009455D0 (en) | 2010-06-04 | 2010-07-21 | King S College London | Nanoparticles and their uses in molecular imaging |
| US9782342B2 (en) | 2010-10-11 | 2017-10-10 | Wichita State University | Composite magnetic nanoparticle drug delivery system |
| BR112013013434A2 (pt) | 2010-12-17 | 2016-08-16 | Arrowhead Res Corp | metade que tem por alvo modulador fármaco cinético em cacho de galactose para sirna |
| PL2670394T3 (pl) | 2011-01-31 | 2019-03-29 | Nanobiotix | Układy do dostarczania nanocząstek, ich otrzymywanie i zastosowania |
| WO2012104277A2 (en) | 2011-01-31 | 2012-08-09 | Nanobiotix | Method of monitoring the release from liposomes of a product of interest using superparamagnetic nanoparticles. |
| US10251841B2 (en) | 2011-10-17 | 2019-04-09 | Trustees Of Boston University | Polymeric depots for localization of agent to biological sites |
| CN102532154B (zh) | 2012-01-11 | 2014-05-14 | 昆明医学院 | 隆萼当归线型呋喃香豆素化合物及其应用 |
| US20150209397A1 (en) | 2012-09-07 | 2015-07-30 | Carnegie Mellon University | Methods and materials for reducing reticuloendothelial system clearance of particles from a subject |
| ITRM20120480A1 (it) | 2012-10-09 | 2014-04-10 | Uni Degli Studi Camerino | Nanoparticelle lipidiche multicomponenti e procedimenti per la loro preparazione. |
| US20140186447A1 (en) | 2012-12-28 | 2014-07-03 | Abraxis Bioscience, Llc | Nanoparticle compositions of albumin and paclitaxel |
| UA116380C2 (uk) * | 2013-05-30 | 2018-03-12 | Нанобіотікс | Посилення терапевтичної або профілактичної ефективності фармацевтичної сполуки |
| EP2886128A1 (en) | 2013-12-20 | 2015-06-24 | Nanobiotix | Pharmaceutical composition comprising nanoparticles, preparation and uses thereof |
| HK1245086A1 (zh) | 2014-11-25 | 2018-08-24 | Nanobiotix | 处方药物组成及其制备和使用 |
| HUE056175T2 (hu) | 2014-11-25 | 2022-01-28 | Curadigm Sas | Gyógyászati készítmények, elõállításuk és alkalmazásaik |
| JP6836510B2 (ja) * | 2014-11-25 | 2021-03-03 | キュラディグム・エスアエスＣｕｒａｄｉｇｍ Ｓａｓ | 少なくとも２つの異なるナノ粒子と医薬化合物とを組み合わせた医薬組成物、その調製及び使用 |
| TW201628656A (zh) | 2014-11-25 | 2016-08-16 | 奈諾生技公司 | 醫藥組合物、其製備與用途 |
| WO2016083331A1 (en) | 2014-11-25 | 2016-06-02 | Nanobiotix | Pharmaceutical composition, preparation and uses thereof |
-
2015
- 2015-11-24 JP JP2017546034A patent/JP6836510B2/ja active Active
- 2015-11-24 WO PCT/EP2015/077446 patent/WO2016083343A1/en not_active Ceased
- 2015-11-24 EP EP15800777.3A patent/EP3229776B1/en active Active
- 2015-11-24 TW TW104139005A patent/TW201628654A/zh unknown
- 2015-11-24 AR ARP150103849A patent/AR102781A1/es unknown
- 2015-11-24 PL PL15800777.3T patent/PL3229776T3/pl unknown
- 2015-11-24 PT PT158007773T patent/PT3229776T/pt unknown
- 2015-11-24 HU HUE15800777A patent/HUE062561T2/hu unknown
- 2015-11-24 LT LTEPPCT/EP2015/077446T patent/LT3229776T/lt unknown
- 2015-11-24 US US15/529,101 patent/US10391058B2/en active Active
- 2015-11-24 FI FIEP15800777.3T patent/FI3229776T3/fi active
- 2015-11-24 DK DK15800777.3T patent/DK3229776T3/da active
- 2015-11-24 ES ES15800777T patent/ES2951598T3/es active Active
-
2019
- 2019-08-26 US US16/550,342 patent/US11471410B2/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| JP2018504450A (ja) | 2018-02-15 |
| US20170258717A1 (en) | 2017-09-14 |
| HUE062561T2 (hu) | 2023-11-28 |
| EP3229776A1 (en) | 2017-10-18 |
| ES2951598T3 (es) | 2023-10-23 |
| DK3229776T3 (da) | 2023-07-31 |
| US10391058B2 (en) | 2019-08-27 |
| US20190374465A1 (en) | 2019-12-12 |
| US11471410B2 (en) | 2022-10-18 |
| LT3229776T (lt) | 2023-08-25 |
| JP6836510B2 (ja) | 2021-03-03 |
| AR102781A1 (es) | 2017-03-22 |
| TW201628654A (zh) | 2016-08-16 |
| EP3229776B1 (en) | 2023-06-28 |
| PT3229776T (pt) | 2023-08-17 |
| PL3229776T3 (pl) | 2023-11-06 |
| WO2016083343A1 (en) | 2016-06-02 |
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