FI3137094T3 - Alzheimerin taudin (ad) hoitaminen ja ehkäiseminen - Google Patents
Alzheimerin taudin (ad) hoitaminen ja ehkäiseminen Download PDFInfo
- Publication number
- FI3137094T3 FI3137094T3 FIEP15720060.1T FI15720060T FI3137094T3 FI 3137094 T3 FI3137094 T3 FI 3137094T3 FI 15720060 T FI15720060 T FI 15720060T FI 3137094 T3 FI3137094 T3 FI 3137094T3
- Authority
- FI
- Finland
- Prior art keywords
- aluminum
- use according
- administered
- oxyhydroxide
- aluminum salt
- Prior art date
Links
- 208000024827 Alzheimer disease Diseases 0.000 title claims 10
- 230000002265 prevention Effects 0.000 title claims 2
- AZDRQVAHHNSJOQ-UHFFFAOYSA-N alumane Chemical class [AlH3] AZDRQVAHHNSJOQ-UHFFFAOYSA-N 0.000 claims 14
- FAHBNUUHRFUEAI-UHFFFAOYSA-M hydroxidooxidoaluminium Chemical group O[Al]=O FAHBNUUHRFUEAI-UHFFFAOYSA-M 0.000 claims 14
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 claims 3
- KCXVZYZYPLLWCC-UHFFFAOYSA-N EDTA Chemical compound OC(=O)CN(CC(O)=O)CCN(CC(O)=O)CC(O)=O KCXVZYZYPLLWCC-UHFFFAOYSA-N 0.000 claims 2
- 239000000725 suspension Substances 0.000 claims 2
- 206010012289 Dementia Diseases 0.000 claims 1
- 239000007983 Tris buffer Substances 0.000 claims 1
- 238000009825 accumulation Methods 0.000 claims 1
- 239000003963 antioxidant agent Substances 0.000 claims 1
- 230000003078 antioxidant effect Effects 0.000 claims 1
- 239000000872 buffer Substances 0.000 claims 1
- 239000003599 detergent Substances 0.000 claims 1
- 239000004615 ingredient Substances 0.000 claims 1
- 238000002347 injection Methods 0.000 claims 1
- 239000007924 injection Substances 0.000 claims 1
- 229910021645 metal ion Inorganic materials 0.000 claims 1
- 239000000825 pharmaceutical preparation Substances 0.000 claims 1
- 239000008363 phosphate buffer Substances 0.000 claims 1
- 239000003381 stabilizer Substances 0.000 claims 1
- 150000005846 sugar alcohols Chemical class 0.000 claims 1
- RTKIYNMVFMVABJ-UHFFFAOYSA-L thimerosal Chemical compound [Na+].CC[Hg]SC1=CC=CC=C1C([O-])=O RTKIYNMVFMVABJ-UHFFFAOYSA-L 0.000 claims 1
- 229960004906 thiomersal Drugs 0.000 claims 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/06—Aluminium, calcium or magnesium; Compounds thereof, e.g. clay
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/06—Aluminium, calcium or magnesium; Compounds thereof, e.g. clay
- A61K33/08—Oxides; Hydroxides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/42—Phosphorus; Compounds thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
Landscapes
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical & Material Sciences (AREA)
- Epidemiology (AREA)
- Inorganic Chemistry (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Neurology (AREA)
- Dermatology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Compounds Of Alkaline-Earth Elements, Aluminum Or Rare-Earth Metals (AREA)
- Medicines Containing Plant Substances (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP14166388 | 2014-04-29 | ||
| EP14166355 | 2014-04-29 | ||
| PCT/EP2015/059341 WO2015165968A1 (en) | 2014-04-29 | 2015-04-29 | Treatment and prevention of alzheimer's disease (ad) |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| FI3137094T3 true FI3137094T3 (fi) | 2023-03-20 |
Family
ID=53039897
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FIEP15720060.1T FI3137094T3 (fi) | 2014-04-29 | 2015-04-29 | Alzheimerin taudin (ad) hoitaminen ja ehkäiseminen |
Country Status (12)
| Country | Link |
|---|---|
| US (3) | US11065273B2 (enExample) |
| EP (2) | EP4209222A1 (enExample) |
| JP (1) | JP2017515812A (enExample) |
| KR (1) | KR102506460B1 (enExample) |
| CN (1) | CN106659736A (enExample) |
| AU (1) | AU2015254665A1 (enExample) |
| CA (1) | CA2946931A1 (enExample) |
| DK (1) | DK3137094T3 (enExample) |
| FI (1) | FI3137094T3 (enExample) |
| PL (1) | PL3137094T3 (enExample) |
| PT (1) | PT3137094T (enExample) |
| WO (1) | WO2015165968A1 (enExample) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106535924A (zh) * | 2014-04-29 | 2017-03-22 | 阿费里斯股份公司 | 阿尔茨海默病(ad)的治疗和预防 |
| KR102506460B1 (ko) | 2014-04-29 | 2023-03-03 | 어드밴티지 테라퓨틱스, 인코포레이티드 | 알츠하이머병（ａｄ）의 치료 및 예방 |
| WO2015165966A1 (en) * | 2014-04-29 | 2015-11-05 | Affiris Ag | Treatment and prevention of alzheimer's disease (ad) |
Family Cites Families (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1994016327A1 (en) | 1993-01-14 | 1994-07-21 | Pollard Harvey B | Methods and compositions for blocking amyloid protein ion channels |
| US6905686B1 (en) | 1997-12-02 | 2005-06-14 | Neuralab Limited | Active immunization for treatment of alzheimer's disease |
| TWI239847B (en) | 1997-12-02 | 2005-09-21 | Elan Pharm Inc | N-terminal fragment of Abeta peptide and an adjuvant for preventing and treating amyloidogenic disease |
| NZ536064A (en) * | 2002-04-19 | 2008-06-30 | Univ Toronto | Immunological methods and compositions for the treatment of alzheimer's disease |
| AT413946B (de) | 2004-07-13 | 2006-07-15 | Mattner Frank Dr | Impfstoff gegen die alzheimer-krankheit |
| US10383887B2 (en) | 2008-02-20 | 2019-08-20 | New York University | Preventing and treating amyloid-beta deposition by stimulation of innate immunity |
| AT506820B1 (de) | 2008-06-12 | 2011-07-15 | Affiris Forschungs Und Entwicklungs Gmbh | Vakzine gegen alzheimer-krankheit |
| AT506819B1 (de) | 2008-06-12 | 2011-06-15 | Affiris Forschungs Und Entwicklungs Gmbh | Vakzin zur behandlung von alzheimer-krankheit |
| EP2145898A1 (en) * | 2008-07-15 | 2010-01-20 | CHIESI FARMACEUTICI S.p.A. | Anti-amyloid immunogenic compositions, methods and uses |
| CN104436212A (zh) | 2010-03-29 | 2015-03-25 | 诺华股份有限公司 | 包含与病毒样颗粒偶联的淀粉样β1-6肽及佐剂的组合物 |
| GB201101331D0 (en) | 2011-01-26 | 2011-03-09 | Glaxosmithkline Biolog Sa | Compositions and uses |
| WO2015165966A1 (en) | 2014-04-29 | 2015-11-05 | Affiris Ag | Treatment and prevention of alzheimer's disease (ad) |
| CN106535924A (zh) | 2014-04-29 | 2017-03-22 | 阿费里斯股份公司 | 阿尔茨海默病(ad)的治疗和预防 |
| KR102506460B1 (ko) | 2014-04-29 | 2023-03-03 | 어드밴티지 테라퓨틱스, 인코포레이티드 | 알츠하이머병（ａｄ）의 치료 및 예방 |
-
2015
- 2015-04-29 KR KR1020167033324A patent/KR102506460B1/ko active Active
- 2015-04-29 PL PL15720060.1T patent/PL3137094T3/pl unknown
- 2015-04-29 CN CN201580029850.7A patent/CN106659736A/zh active Pending
- 2015-04-29 DK DK15720060.1T patent/DK3137094T3/da active
- 2015-04-29 CA CA2946931A patent/CA2946931A1/en not_active Abandoned
- 2015-04-29 JP JP2016565334A patent/JP2017515812A/ja active Pending
- 2015-04-29 PT PT157200601T patent/PT3137094T/pt unknown
- 2015-04-29 WO PCT/EP2015/059341 patent/WO2015165968A1/en not_active Ceased
- 2015-04-29 EP EP22211552.9A patent/EP4209222A1/en active Pending
- 2015-04-29 EP EP15720060.1A patent/EP3137094B1/en active Active
- 2015-04-29 AU AU2015254665A patent/AU2015254665A1/en not_active Abandoned
- 2015-04-29 US US15/307,246 patent/US11065273B2/en active Active
- 2015-04-29 FI FIEP15720060.1T patent/FI3137094T3/fi active
-
2021
- 2021-07-08 US US17/370,615 patent/US11857568B2/en active Active
-
2023
- 2023-11-20 US US18/514,612 patent/US20240148782A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| KR102506460B1 (ko) | 2023-03-03 |
| JP2017515812A (ja) | 2017-06-15 |
| EP3137094B1 (en) | 2022-12-07 |
| EP3137094A1 (en) | 2017-03-08 |
| US11857568B2 (en) | 2024-01-02 |
| CN106659736A (zh) | 2017-05-10 |
| US11065273B2 (en) | 2021-07-20 |
| AU2015254665A1 (en) | 2016-11-10 |
| PT3137094T (pt) | 2023-03-09 |
| DK3137094T3 (da) | 2023-02-27 |
| US20220000908A1 (en) | 2022-01-06 |
| CA2946931A1 (en) | 2015-11-05 |
| WO2015165968A1 (en) | 2015-11-05 |
| EP4209222A1 (en) | 2023-07-12 |
| US20170049810A1 (en) | 2017-02-23 |
| KR20160145821A (ko) | 2016-12-20 |
| US20240148782A1 (en) | 2024-05-09 |
| PL3137094T3 (pl) | 2023-03-13 |
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