FI20115876A0 - Yhdistelmähoito - Google Patents

Yhdistelmähoito

Info

Publication number
FI20115876A0
FI20115876A0 FI20115876A FI20115876A FI20115876A0 FI 20115876 A0 FI20115876 A0 FI 20115876A0 FI 20115876 A FI20115876 A FI 20115876A FI 20115876 A FI20115876 A FI 20115876A FI 20115876 A0 FI20115876 A0 FI 20115876A0
Authority
FI
Finland
Prior art keywords
combination therapy
therapy
combination
Prior art date
Application number
FI20115876A
Other languages
English (en)
Finnish (fi)
Swedish (sv)
Inventor
Jukka Westermarck
Anna Cvrljevic
Original Assignee
Turun Yliopisto
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Turun Yliopisto filed Critical Turun Yliopisto
Priority to FI20115876A priority Critical patent/FI20115876A0/fi
Publication of FI20115876A0 publication Critical patent/FI20115876A0/fi
Priority to EP17199400.7A priority patent/EP3311815A1/en
Priority to JP2014529039A priority patent/JP6060164B2/ja
Priority to US14/343,015 priority patent/US9457042B2/en
Priority to EP12762321.3A priority patent/EP2753316B1/en
Priority to CN201280054472.4A priority patent/CN103917228B/zh
Priority to DK12762321.3T priority patent/DK2753316T3/en
Priority to CA2847810A priority patent/CA2847810C/en
Priority to PCT/FI2012/050862 priority patent/WO2013034806A1/en
Priority to ES12762321.3T priority patent/ES2650742T3/es
Priority to US15/254,312 priority patent/US9968630B2/en

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7088—Compounds having three or more nucleosides or nucleotides
    • A61K31/713—Double-stranded nucleic acids or oligonucleotides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/24—Heavy metals; Compounds thereof
    • A61K33/243—Platinum; Compounds thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A—HUMAN NECESSITIES
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/075—Ethers or acetals
    • A61K31/085—Ethers or acetals having an ether linkage to aromatic ring nuclear carbon
    • A61K31/09—Ethers or acetals having an ether linkage to aromatic ring nuclear carbon having two or more such linkages
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K31/13—Amines
    • A61K31/15—Oximes (>C=N—O—); Hydrazines (>N—N<); Hydrazones (>N—N=) ; Imines (C—N=C)
    • A—HUMAN NECESSITIES
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • A—HUMAN NECESSITIES
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    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • A61K31/166—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the carbon of a carboxamide group directly attached to the aromatic ring, e.g. procainamide, procarbazine, metoclopramide, labetalol
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    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/235—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids having an aromatic ring attached to a carboxyl group
    • A61K31/24—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids having an aromatic ring attached to a carboxyl group having an amino or nitro group
    • A61K31/245—Amino benzoic acid types, e.g. procaine, novocaine
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    • A61K31/337—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having four-membered rings, e.g. taxol
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    • A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
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    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4164—1,3-Diazoles
    • A61K31/4188—1,3-Diazoles condensed with other heterocyclic ring systems, e.g. biotin, sorbinil
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    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/436—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a six-membered ring having oxygen as a ring hetero atom, e.g. rapamycin
    • A—HUMAN NECESSITIES
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    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4406—Non condensed pyridines; Hydrogenated derivatives thereof only substituted in position 3, e.g. zimeldine
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    • A61K31/444—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a six-membered ring with nitrogen as a ring heteroatom, e.g. amrinone
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FI20115876A 2011-09-06 2011-09-06 Yhdistelmähoito FI20115876A0 (fi)

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Application Number Priority Date Filing Date Title
FI20115876A FI20115876A0 (fi) 2011-09-06 2011-09-06 Yhdistelmähoito
ES12762321.3T ES2650742T3 (es) 2011-09-06 2012-09-06 Combinación farmacéutica que comprende un agente de silenciamiento de CIP2A para usar en el tratamiento de un trastorno hiperproliferativo, preferiblemente uno con la función p53 deteriorada
EP12762321.3A EP2753316B1 (en) 2011-09-06 2012-09-06 Pharmaceutical combination comprising a cip2a silencing agent for use in the treatment of a hyperproliferative disorder, preferably one with impaired p53 function
JP2014529039A JP6060164B2 (ja) 2011-09-06 2012-09-06 過剰増殖性疾患、好ましくはｐ５３機能欠損の治療に用いるためのＣＩＰ２Ａサイレンシング剤を含む併用薬剤
US14/343,015 US9457042B2 (en) 2011-09-06 2012-09-06 Pharmaceutical combination comprising a CIP2A silencing agent for use in the treatment of a hyperproliferative disorder, preferably one with impaired p53 function
EP17199400.7A EP3311815A1 (en) 2011-09-06 2012-09-06 Pharmaceutical combination comprising a cip2a silencing agent for use in the treatment of a hyperproliferative disorder with impaired p53 function.
CN201280054472.4A CN103917228B (zh) 2011-09-06 2012-09-06 用于治疗过度增生性障碍、优选具有受损的p53功能的过度增生性障碍的包含CIP2A沉默剂的药物组合
DK12762321.3T DK2753316T3 (en) 2011-09-06 2012-09-06 PHARMACEUTICAL COMBINATION INCLUDING A CIP2A SILENCING AGENT TO USE IN THE TREATMENT OF A HYPERPROLIFERATIVE DISORDER, PRIOR TO AN IMPAIRED P53 FUNCTION
CA2847810A CA2847810C (en) 2011-09-06 2012-09-06 Pharmaceutical combination comprising a cip2a silencing agent for use in the treatment of a hyperproliferative disorder, preferably one with impaired p53 function
PCT/FI2012/050862 WO2013034806A1 (en) 2011-09-06 2012-09-06 Pharmaceutical combination comprising a cip2a silencing agent for use in the treatment of a hyperproliferative disorder, preferably one with impaired p53 function
US15/254,312 US9968630B2 (en) 2011-09-06 2016-09-01 Pharmaceutical combination comprising a CIP2A silencing agent for use in the treatment of a hyperproliferative disorder, preferably one with impaired P53 function

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CN111549033B (zh) * 2020-06-11 2021-02-12 南京市江宁医院 慢病毒感染人表皮角质细胞株及其构建方法和应用
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CN103917228A (zh) 2014-07-09
EP2753316A1 (en) 2014-07-16
JP2014526456A (ja) 2014-10-06
WO2013034806A1 (en) 2013-03-14
EP3311815A1 (en) 2018-04-25
DK2753316T3 (en) 2017-12-11
US9968630B2 (en) 2018-05-15
CA2847810C (en) 2020-07-07
US20140199415A1 (en) 2014-07-17
CA2847810A1 (en) 2013-03-14
CN103917228B (zh) 2018-04-20
ES2650742T3 (es) 2018-01-22
JP6060164B2 (ja) 2017-01-11
US9457042B2 (en) 2016-10-04

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