FI20080326A0 - Neurotroofinen tekijä MANF ja sen käytöt - Google Patents

Neurotroofinen tekijä MANF ja sen käytöt

Info

Publication number
FI20080326A0
FI20080326A0 FI20080326A FI20080326A FI20080326A0 FI 20080326 A0 FI20080326 A0 FI 20080326A0 FI 20080326 A FI20080326 A FI 20080326A FI 20080326 A FI20080326 A FI 20080326A FI 20080326 A0 FI20080326 A0 FI 20080326A0
Authority
FI
Finland
Prior art keywords
neurotrophic factor
manf
factor manf
neurotrophic
factor
Prior art date
Application number
FI20080326A
Other languages
English (en)
Finnish (fi)
Swedish (sv)
Inventor
Mart Saarma
Paeivi Lindholm
Merja Voutilainen
Johan Peraenen
Raimo Tuominen
Mikko Airavaara
Veli-Matti Leppaenen
Maria Lindahl
Jaan-Olle Andressoo
Original Assignee
Licentia Oy
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Licentia Oy filed Critical Licentia Oy
Priority to FI20080326A priority Critical patent/FI20080326A0/fi
Publication of FI20080326A0 publication Critical patent/FI20080326A0/fi
Priority to US12/433,345 priority patent/US8853166B2/en
Priority to DK09738284.0T priority patent/DK2276778T3/en
Priority to ES09738284.0T priority patent/ES2530222T3/es
Priority to PCT/FI2009/050346 priority patent/WO2009133247A1/fr
Priority to CA2725128A priority patent/CA2725128C/fr
Priority to EP09738284.0A priority patent/EP2276778B1/fr
Priority to US14/480,975 priority patent/US9592270B2/en
Priority to HRP20150095AT priority patent/HRP20150095T1/hr

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/18—Growth factors; Growth regulators
    • A61K38/185—Nerve growth factor [NGF]; Brain derived neurotrophic factor [BDNF]; Ciliary neurotrophic factor [CNTF]; Glial derived neurotrophic factor [GDNF]; Neurotrophins, e.g. NT-3
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K67/00—Rearing or breeding animals, not otherwise provided for; New or modified breeds of animals
    • A01K67/027—New or modified breeds of vertebrates
    • A01K67/0275—Genetically modified vertebrates, e.g. transgenic
    • A01K67/0278—Knock-in vertebrates, e.g. humanised vertebrates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/475—Growth factors; Growth regulators
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2227/00—Animals characterised by species
    • A01K2227/10—Mammal
    • A01K2227/105—Murine
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2267/00—Animals characterised by purpose
    • A01K2267/03—Animal model, e.g. for test or diseases
    • A01K2267/035—Animal model for multifactorial diseases
    • A01K2267/0356—Animal model for processes and diseases of the central nervous system, e.g. stress, learning, schizophrenia, pain, epilepsy
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Zoology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Psychology (AREA)
  • Environmental Sciences (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Toxicology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Biotechnology (AREA)
  • Animal Husbandry (AREA)
  • Biodiversity & Conservation Biology (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
FI20080326A 2008-04-30 2008-04-30 Neurotroofinen tekijä MANF ja sen käytöt FI20080326A0 (fi)

Priority Applications (9)

Application Number Priority Date Filing Date Title
FI20080326A FI20080326A0 (fi) 2008-04-30 2008-04-30 Neurotroofinen tekijä MANF ja sen käytöt
US12/433,345 US8853166B2 (en) 2008-04-30 2009-04-30 Neurotrophic factor MANF and uses thereof
DK09738284.0T DK2276778T3 (en) 2008-04-30 2009-04-30 Neurotrophic factor MANF as well as applications thereof
ES09738284.0T ES2530222T3 (es) 2008-04-30 2009-04-30 Factor neurotrófico MANF y usos del mismo
PCT/FI2009/050346 WO2009133247A1 (fr) 2008-04-30 2009-04-30 Facteur neurotrophique manf et ses utilisations
CA2725128A CA2725128C (fr) 2008-04-30 2009-04-30 Facteur neurotrophique manf et ses utilisations
EP09738284.0A EP2276778B1 (fr) 2008-04-30 2009-04-30 Facteur neurotrophique manf et ses utilisations
US14/480,975 US9592270B2 (en) 2008-04-30 2014-09-09 Neurotrophic factor MANF and uses thereof
HRP20150095AT HRP20150095T1 (en) 2008-04-30 2015-01-26 Neurotrophic factor manf and uses thereof

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FI20080326A FI20080326A0 (fi) 2008-04-30 2008-04-30 Neurotroofinen tekijä MANF ja sen käytöt

Publications (1)

Publication Number Publication Date
FI20080326A0 true FI20080326A0 (fi) 2008-04-30

Family

ID=39385893

Family Applications (1)

Application Number Title Priority Date Filing Date
FI20080326A FI20080326A0 (fi) 2008-04-30 2008-04-30 Neurotroofinen tekijä MANF ja sen käytöt

Country Status (8)

Country Link
US (2) US8853166B2 (fr)
EP (1) EP2276778B1 (fr)
CA (1) CA2725128C (fr)
DK (1) DK2276778T3 (fr)
ES (1) ES2530222T3 (fr)
FI (1) FI20080326A0 (fr)
HR (1) HRP20150095T1 (fr)
WO (1) WO2009133247A1 (fr)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK1373502T3 (da) 2001-03-20 2011-01-10 Amarantus Therapeutics Inc Dopaminerge neuronale overlevelsesfremmende faktorer og avendelser heraf
BRPI0909221A2 (pt) * 2008-03-25 2015-08-11 Amarantus Therapeutics Inc Desordens neurodegenerativas
WO2010042728A1 (fr) * 2008-10-08 2010-04-15 Cornell University Modulateurs à petite molécule d'une absorption de prongf
EP2684050B1 (fr) * 2011-03-11 2016-05-11 Roche Diagnostics GmbH Armet en tant que marqueur pour une maladie pulmonaire obstructive chronique (copd)
ES2594605T3 (es) * 2011-06-09 2016-12-21 University Of Miami Factores neurotróficos MANF y CDNF para uso en el tratamiento de trastornos de la retina
FI20115870A0 (fi) * 2011-09-05 2011-09-05 Urmas Arumaee Neuroprotektiiviset soluihin tunkeutuvat peptidit
US9891231B2 (en) * 2012-01-24 2018-02-13 University Of Massachusetts Soluble MANF in pancreatic β-cell disorders
WO2014066686A1 (fr) * 2012-10-24 2014-05-01 Amarantus Bioscience Holdings, Inc. Cibles cérébrales pour facteurs neurotrophiques en vue de traiter une maladie neurodégénérative
WO2014191630A2 (fr) * 2013-05-28 2014-12-04 Helsingin Yliopisto Modèle animal non humain codant pour un gène manf non fonctionnel
WO2015061856A1 (fr) 2013-10-30 2015-05-07 University Of Western Australia Peptides neuroprotecteurs
CN105315359A (zh) * 2014-07-31 2016-02-10 北京泳健生物技术有限公司 一种缺失型重组人中脑星形胶质细胞源性神经营养因子
WO2016057579A1 (fr) * 2014-10-06 2016-04-14 Amarantus Bioscience Holdings, Inc. Méthodes et compositions de traitement de troubles rétiniens
EP3377089B1 (fr) 2015-11-18 2020-04-08 Herantis Pharma Plc Compositions comprenant du cdnf pour le traitement par voie intranasale de maladies du système nerveux central
CN107190102A (zh) * 2016-05-09 2017-09-22 上海市同济医院 一种用于人源性manf基因检测的地高辛探针及其应用
EP3619227A1 (fr) 2017-05-04 2020-03-11 Helsingin Yliopisto Fragments cdnf et manf c-terminaux, compositions pharmaceutiques les comprenant et leurs utilisations
MX2020010301A (es) 2018-03-29 2020-10-20 Helsingin Yliopisto Fragmentos de cdnf c-terminales, composiciones farmaceuticas que los comprenden y usos de los mismos.
EP3838345A1 (fr) 2019-12-20 2021-06-23 Herantis Pharma Oyj Peptides macrocycliques
EP3838912A1 (fr) 2019-12-20 2021-06-23 Herantis Pharma Oyj Peptides rétro inverses
CN113292656B (zh) * 2020-02-21 2022-10-25 四川大学华西医院 用于防治肥胖的中脑星形胶质细胞源性神经营养因子的融合蛋白
EP4223307A1 (fr) * 2020-09-29 2023-08-09 Cefo Co., Ltd. Composition pour la prévention ou le traitement d'une maladie neuropsychologique, comprenant manf
CN115887619B (zh) * 2021-09-30 2024-03-26 四川大学 中脑星形胶质细胞源性神经营养因子的用途及药物组合物
GB202202898D0 (en) * 2022-03-02 2022-04-13 Babraham Inst Novel use
WO2023212658A2 (fr) * 2022-04-27 2023-11-02 Amarantus Bioscience Holdings Compositions pour le traitement de complications liées à une maladie infectieuse et procédés associés
WO2024030951A2 (fr) * 2022-08-03 2024-02-08 The Trustees Of Columbia University In The City Of New York Facteur neurotrophique dérivé d'astrocytes mésencéphaliques (manf) pour prévenir et traiter des neuropathies périphériques

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Also Published As

Publication number Publication date
HRP20150095T1 (en) 2015-03-13
US20150020222A1 (en) 2015-01-15
EP2276778A1 (fr) 2011-01-26
US9592270B2 (en) 2017-03-14
CA2725128A1 (fr) 2009-11-05
US8853166B2 (en) 2014-10-07
US20090282495A1 (en) 2009-11-12
DK2276778T3 (en) 2015-02-09
EP2276778B1 (fr) 2014-11-12
ES2530222T3 (es) 2015-02-27
EP2276778A4 (fr) 2011-07-06
WO2009133247A1 (fr) 2009-11-05
CA2725128C (fr) 2018-04-24

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