FI110839B - Menetelmä ja mittauslaitteisto uloshengitysilman typpioksidipitoisuuden mittaamiseksi - Google Patents
Menetelmä ja mittauslaitteisto uloshengitysilman typpioksidipitoisuuden mittaamiseksi Download PDFInfo
- Publication number
- FI110839B FI110839B FI20011000A FI20011000A FI110839B FI 110839 B FI110839 B FI 110839B FI 20011000 A FI20011000 A FI 20011000A FI 20011000 A FI20011000 A FI 20011000A FI 110839 B FI110839 B FI 110839B
- Authority
- FI
- Finland
- Prior art keywords
- measuring
- flow
- air
- exhaled air
- oxide content
- Prior art date
Links
- MWUXSHHQAYIFBG-UHFFFAOYSA-N Nitric oxide Chemical compound O=[N] MWUXSHHQAYIFBG-UHFFFAOYSA-N 0.000 title claims abstract description 182
- 238000000034 method Methods 0.000 title claims abstract description 16
- 238000005259 measurement Methods 0.000 claims description 26
- 238000007664 blowing Methods 0.000 claims description 23
- 230000001276 controlling effect Effects 0.000 claims 1
- 230000001105 regulatory effect Effects 0.000 claims 1
- 206010001889 Alveolitis Diseases 0.000 abstract description 6
- 201000001155 extrinsic allergic alveolitis Diseases 0.000 abstract description 6
- 208000022098 hypersensitivity pneumonitis Diseases 0.000 abstract description 6
- 230000002757 inflammatory effect Effects 0.000 abstract description 4
- 208000019693 Lung disease Diseases 0.000 abstract description 3
- 210000004072 lung Anatomy 0.000 description 12
- 206010061218 Inflammation Diseases 0.000 description 7
- 230000004054 inflammatory process Effects 0.000 description 7
- 208000006673 asthma Diseases 0.000 description 6
- 238000004519 manufacturing process Methods 0.000 description 6
- 230000006870 function Effects 0.000 description 4
- 230000007423 decrease Effects 0.000 description 3
- 238000009792 diffusion process Methods 0.000 description 3
- 230000004907 flux Effects 0.000 description 3
- IJGRMHOSHXDMSA-UHFFFAOYSA-N Atomic nitrogen Chemical compound N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 description 2
- 206010035664 Pneumonia Diseases 0.000 description 2
- 210000000038 chest Anatomy 0.000 description 2
- 238000005516 engineering process Methods 0.000 description 2
- 238000012545 processing Methods 0.000 description 2
- 230000000241 respiratory effect Effects 0.000 description 2
- 210000002345 respiratory system Anatomy 0.000 description 2
- 210000001519 tissue Anatomy 0.000 description 2
- MGWGWNFMUOTEHG-UHFFFAOYSA-N 4-(3,5-dimethylphenyl)-1,3-thiazol-2-amine Chemical compound CC1=CC(C)=CC(C=2N=C(N)SC=2)=C1 MGWGWNFMUOTEHG-UHFFFAOYSA-N 0.000 description 1
- 206010006322 Breath holding Diseases 0.000 description 1
- 241000282472 Canis lupus familiaris Species 0.000 description 1
- 201000009794 Idiopathic Pulmonary Fibrosis Diseases 0.000 description 1
- 125000002066 L-histidyl group Chemical group [H]N1C([H])=NC(C([H])([H])[C@](C(=O)[*])([H])N([H])[H])=C1[H] 0.000 description 1
- CBENFWSGALASAD-UHFFFAOYSA-N Ozone Chemical compound [O-][O+]=O CBENFWSGALASAD-UHFFFAOYSA-N 0.000 description 1
- 238000004364 calculation method Methods 0.000 description 1
- 238000004891 communication Methods 0.000 description 1
- 238000001514 detection method Methods 0.000 description 1
- 238000002474 experimental method Methods 0.000 description 1
- 208000027866 inflammatory disease Diseases 0.000 description 1
- 238000013178 mathematical model Methods 0.000 description 1
- 238000012544 monitoring process Methods 0.000 description 1
- 210000000214 mouth Anatomy 0.000 description 1
- 210000003928 nasal cavity Anatomy 0.000 description 1
- 210000001989 nasopharynx Anatomy 0.000 description 1
- 229910052757 nitrogen Inorganic materials 0.000 description 1
- JCXJVPUVTGWSNB-UHFFFAOYSA-N nitrogen dioxide Inorganic materials O=[N]=O JCXJVPUVTGWSNB-UHFFFAOYSA-N 0.000 description 1
- 230000003287 optical effect Effects 0.000 description 1
- 238000005192 partition Methods 0.000 description 1
- 230000001991 pathophysiological effect Effects 0.000 description 1
- 238000007639 printing Methods 0.000 description 1
- 230000002685 pulmonary effect Effects 0.000 description 1
- 208000005069 pulmonary fibrosis Diseases 0.000 description 1
- 230000029058 respiratory gaseous exchange Effects 0.000 description 1
- 230000036387 respiratory rate Effects 0.000 description 1
- 230000011664 signaling Effects 0.000 description 1
- 210000001584 soft palate Anatomy 0.000 description 1
- 210000000115 thoracic cavity Anatomy 0.000 description 1
- 238000009423 ventilation Methods 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/41—Detecting, measuring or recording for evaluating the immune or lymphatic systems
- A61B5/411—Detecting or monitoring allergy or intolerance reactions to an allergenic agent or substance
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/08—Detecting, measuring or recording devices for evaluating the respiratory organs
- A61B5/082—Evaluation by breath analysis, e.g. determination of the chemical composition of exhaled breath
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/08—Detecting, measuring or recording devices for evaluating the respiratory organs
- A61B5/083—Measuring rate of metabolism by using breath test, e.g. measuring rate of oxygen consumption
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/483—Physical analysis of biological material
- G01N33/497—Physical analysis of biological material of gaseous biological material, e.g. breath
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/0004—Gaseous mixtures, e.g. polluted air
- G01N33/0009—General constructional details of gas analysers, e.g. portable test equipment
- G01N33/0027—General constructional details of gas analysers, e.g. portable test equipment concerning the detector
- G01N33/0036—General constructional details of gas analysers, e.g. portable test equipment concerning the detector specially adapted to detect a particular component
- G01N33/0037—NOx
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/20—Air quality improvement or preservation, e.g. vehicle emission control or emission reduction by using catalytic converters
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Physics & Mathematics (AREA)
- Biomedical Technology (AREA)
- General Health & Medical Sciences (AREA)
- Biophysics (AREA)
- Pathology (AREA)
- Veterinary Medicine (AREA)
- Heart & Thoracic Surgery (AREA)
- Surgery (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Medical Informatics (AREA)
- Chemical & Material Sciences (AREA)
- Pulmonology (AREA)
- Physiology (AREA)
- Immunology (AREA)
- Analytical Chemistry (AREA)
- Vascular Medicine (AREA)
- Medicinal Chemistry (AREA)
- Urology & Nephrology (AREA)
- Biochemistry (AREA)
- General Physics & Mathematics (AREA)
- Hematology (AREA)
- Food Science & Technology (AREA)
- Emergency Medicine (AREA)
- Obesity (AREA)
- Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Sampling And Sample Adjustment (AREA)
- Measuring Volume Flow (AREA)
- Investigating Or Analyzing Non-Biological Materials By The Use Of Chemical Means (AREA)
- Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
Priority Applications (11)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FI20011000A FI110839B (fi) | 2001-05-11 | 2001-05-11 | Menetelmä ja mittauslaitteisto uloshengitysilman typpioksidipitoisuuden mittaamiseksi |
| EP02722316A EP1389950B1 (en) | 2001-05-11 | 2002-05-07 | Method and measuring equipment for measuring nitric oxide concentration in exhaled air |
| AT02722316T ATE378005T1 (de) | 2001-05-11 | 2002-05-07 | Verfahren und messgerät zur messung der stickoxidkonzentration in der ausatemluft |
| AU2002253206A AU2002253206B2 (en) | 2001-05-11 | 2002-05-07 | Method and measuring equipment for measuring nitric oxide concentration in exhaled air |
| ES02722316T ES2296917T3 (es) | 2001-05-11 | 2002-05-07 | Metodo y equipo de medicion de la concentracion de oxido nitrico en aire espirado. |
| JP2002588843A JP4235455B2 (ja) | 2001-05-11 | 2002-05-07 | 呼気の一酸化窒素濃度を測定するための方法および測定装置 |
| PCT/FI2002/000389 WO2002091921A1 (en) | 2001-05-11 | 2002-05-07 | Method and measuring equipment for measuring nitric oxide concentration in exhaled air |
| DE60223527T DE60223527T2 (de) | 2001-05-11 | 2002-05-07 | Verfahren und messgerät zur messung der stickoxidkonzentration in der ausatemluft |
| CA2445739A CA2445739C (en) | 2001-05-11 | 2002-05-07 | Method and measuring equipment for measuring nitric oxide concentration in exhaled air |
| US10/145,036 US6733463B2 (en) | 2001-05-11 | 2002-05-15 | Method and measuring equipment for measuring nitric oxide concentration in exhaled air |
| JP2008218395A JP4778544B2 (ja) | 2001-05-11 | 2008-08-27 | 呼気の一酸化窒素濃度を測定するための方法および測定装置 |
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FI20011000A FI110839B (fi) | 2001-05-11 | 2001-05-11 | Menetelmä ja mittauslaitteisto uloshengitysilman typpioksidipitoisuuden mittaamiseksi |
| FI20011000 | 2001-05-11 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| FI20011000A0 FI20011000A0 (fi) | 2001-05-11 |
| FI20011000A FI20011000A (fi) | 2002-11-12 |
| FI110839B true FI110839B (fi) | 2003-04-15 |
Family
ID=8561185
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FI20011000A FI110839B (fi) | 2001-05-11 | 2001-05-11 | Menetelmä ja mittauslaitteisto uloshengitysilman typpioksidipitoisuuden mittaamiseksi |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US6733463B2 (es) |
| EP (1) | EP1389950B1 (es) |
| JP (2) | JP4235455B2 (es) |
| AT (1) | ATE378005T1 (es) |
| AU (1) | AU2002253206B2 (es) |
| CA (1) | CA2445739C (es) |
| DE (1) | DE60223527T2 (es) |
| ES (1) | ES2296917T3 (es) |
| FI (1) | FI110839B (es) |
| WO (1) | WO2002091921A1 (es) |
Families Citing this family (35)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FI110839B (fi) * | 2001-05-11 | 2003-04-15 | Lauri Lehtimaeki | Menetelmä ja mittauslaitteisto uloshengitysilman typpioksidipitoisuuden mittaamiseksi |
| JP2005516704A (ja) * | 2002-02-05 | 2005-06-09 | ザ、リージェンツ、オブ、ザ、ユニバーシティ、オブ、カリフォルニア | 換気呼吸の呼気曲線に基づく流量非依存パラメータの推定 |
| WO2005006988A1 (en) | 2003-06-19 | 2005-01-27 | Everest Biomedical Instruments | Breath end-tidal gas monitor |
| US20050053549A1 (en) * | 2003-09-10 | 2005-03-10 | Aperon Biosystems Corp. | Method for treating airway disorders |
| EP1728072A1 (en) * | 2004-03-03 | 2006-12-06 | Koninklijke Philips Electronics N.V. | Detection of no with a semi-conducting compound and a sensor and device to detect no |
| JP4530212B2 (ja) * | 2004-09-28 | 2010-08-25 | 株式会社タニタ | 呼気分析装置 |
| GB2421442B (en) * | 2004-11-22 | 2008-04-16 | Mark Varney | Tidal gas resuscitation monitor |
| US20060177889A1 (en) * | 2005-02-05 | 2006-08-10 | Aperon Biosystems Corp. | Rapid responding gas sensing element |
| US20060178592A1 (en) | 2005-02-07 | 2006-08-10 | Aperson Biosystems Corp. | System and method for controlling the flow of exhaled breath during analysis |
| US20070282214A1 (en) * | 2006-05-16 | 2007-12-06 | The Regents Of The University Of California | Technique to characterize proximal and peripheral nitric oxide exchange using constant flow exhalations and an axial diffusion model |
| EP2062046A4 (en) * | 2006-09-14 | 2010-10-06 | Res Foundation Of The State Un | PROOF OF STICK OXIDE |
| GB0717433D0 (en) * | 2007-09-07 | 2007-10-17 | Bedfont Scient Ltd | Apparatus and method |
| US8425428B2 (en) * | 2008-03-31 | 2013-04-23 | Covidien Lp | Nitric oxide measurements in patients using flowfeedback |
| US20120123288A1 (en) * | 2009-07-30 | 2012-05-17 | Koninklijke Philips Electronics N.V. | Method and apparatus of determining exhaled nitric oxide |
| US11534081B2 (en) | 2009-08-06 | 2022-12-27 | Peter Theophilos Banos | Methods of and devices for monitoring the effects of cellular stress and damage resulting from radiation exposure |
| US20110301483A1 (en) * | 2009-12-23 | 2011-12-08 | Pulmonx Corporation | Local lung measurement and treatment |
| JP5931748B2 (ja) * | 2010-02-17 | 2016-06-08 | コーニンクレッカ フィリップス エヌ ヴェＫｏｎｉｎｋｌｉｊｋｅ Ｐｈｉｌｉｐｓ Ｎ．Ｖ． | 一酸化窒素測定方法及び装置 |
| US8621911B2 (en) | 2010-05-14 | 2014-01-07 | William J. McFaul | Method and system for determining levels of gases |
| WO2012032183A1 (en) * | 2010-09-10 | 2012-03-15 | Umc Utrecht Holding B.V. | Measurement device for lung function measurement |
| WO2013026902A1 (en) | 2011-08-23 | 2013-02-28 | Aerocrine Ab | Devices and methods for generating an artificial exhalation profile |
| WO2013070545A1 (en) | 2011-11-07 | 2013-05-16 | Landy Toth | Metabolic and cardiopulmonary monitor |
| CN107874761A (zh) | 2011-12-21 | 2018-04-06 | 卡普尼亚公司 | 在补偿呼吸参数频率的情况下收集并分析一定体积的呼出的气体 |
| CA2857251C (en) | 2011-12-22 | 2020-06-16 | Aerocrine Ab | Method and device for measuring a component in exhaled breath |
| US9164080B2 (en) | 2012-06-11 | 2015-10-20 | Ohio State Innovation Foundation | System and method for sensing NO |
| CN104883971B (zh) * | 2012-09-28 | 2018-10-16 | 代表亚利桑那州大学行事的亚利桑那州大学董事会 | 用于精确检测呼出的一氧化氮的吹嘴 |
| MX2015008838A (es) | 2013-01-08 | 2015-12-15 | Capnia Inc | Seleccion de respiracion para analisis. |
| CN105101873A (zh) | 2013-02-12 | 2015-11-25 | 卡普尼亚公司 | 用于呼吸气体分析的采样和存储注册装置 |
| EP3038530B1 (en) | 2013-08-30 | 2020-03-25 | Capnia, Inc. | Neonatal carbon dioxide measurement system and method |
| US10307080B2 (en) | 2014-03-07 | 2019-06-04 | Spirosure, Inc. | Respiratory monitor |
| US10568568B2 (en) | 2014-08-27 | 2020-02-25 | Capnia, Inc. | Methods for immune globulin administration |
| ES2579911B2 (es) * | 2016-05-27 | 2016-12-29 | Eversens, S.L. | Dispositivo de medida de la concentración de gases en aire exhalado y procedimiento de medida empleado |
| US11300552B2 (en) | 2017-03-01 | 2022-04-12 | Caire Diagnostics Inc. | Nitric oxide detection device with reducing gas |
| CN110833415A (zh) * | 2018-08-15 | 2020-02-25 | 深圳市美好创亿医疗科技有限公司 | 呼气no检测系统 |
| KR20220123086A (ko) * | 2019-12-31 | 2022-09-05 | 맥닐 에이비 | 호흡 센서 측정 방법 및 장치 |
| CN114814103A (zh) * | 2022-04-28 | 2022-07-29 | 青岛华仁医疗用品有限公司 | 一种离线呼出气一氧化氮检测装置 |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS62188969A (ja) * | 1986-02-14 | 1987-08-18 | Toray Ind Inc | 呼気分析方法 |
| DK0724723T3 (da) * | 1993-07-06 | 2000-10-23 | Kjell Alving | System til bestemmelse af NO-Nivveauer i udåndet luft og diagnostiske metoder til forstyrrelser relateret tilunormale NO-ni |
| DE19545794C2 (de) * | 1995-12-08 | 1998-03-19 | Draegerwerk Ag | Gasprobenahmesystem mit einem Mundstück |
| DE892926T1 (de) * | 1996-04-09 | 1999-12-09 | Sievers Instruments, Inc. | Verfahren und vorrichtung zur messung von bestandteilen in von menschen ausgeatmeter luft |
| SE9701150D0 (sv) | 1997-03-27 | 1997-03-27 | Nitrograf Ab | Anordning för att utvärdera NO-halten i en utandad luftström |
| SE9902377D0 (sv) * | 1999-06-22 | 1999-06-22 | Aerocrine Ab | Gasflödesregulator |
| AU2001261085A1 (en) * | 2000-04-29 | 2001-11-12 | The Regents Of The University Of California | An apparatus and method for the estimation of flow-independent parameters which characterize the relevant features of nitric oxide production and exchange in the human lungs |
| FI110839B (fi) * | 2001-05-11 | 2003-04-15 | Lauri Lehtimaeki | Menetelmä ja mittauslaitteisto uloshengitysilman typpioksidipitoisuuden mittaamiseksi |
-
2001
- 2001-05-11 FI FI20011000A patent/FI110839B/fi not_active IP Right Cessation
-
2002
- 2002-05-07 WO PCT/FI2002/000389 patent/WO2002091921A1/en active IP Right Grant
- 2002-05-07 EP EP02722316A patent/EP1389950B1/en not_active Expired - Lifetime
- 2002-05-07 DE DE60223527T patent/DE60223527T2/de not_active Expired - Lifetime
- 2002-05-07 AU AU2002253206A patent/AU2002253206B2/en not_active Ceased
- 2002-05-07 ES ES02722316T patent/ES2296917T3/es not_active Expired - Lifetime
- 2002-05-07 JP JP2002588843A patent/JP4235455B2/ja not_active Expired - Lifetime
- 2002-05-07 CA CA2445739A patent/CA2445739C/en not_active Expired - Lifetime
- 2002-05-07 AT AT02722316T patent/ATE378005T1/de not_active IP Right Cessation
- 2002-05-15 US US10/145,036 patent/US6733463B2/en not_active Expired - Lifetime
-
2008
- 2008-08-27 JP JP2008218395A patent/JP4778544B2/ja not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| CA2445739C (en) | 2011-07-12 |
| AU2002253206B2 (en) | 2006-04-27 |
| US6733463B2 (en) | 2004-05-11 |
| DE60223527D1 (de) | 2007-12-27 |
| WO2002091921A1 (en) | 2002-11-21 |
| JP2004529712A (ja) | 2004-09-30 |
| CA2445739A1 (en) | 2002-11-21 |
| ES2296917T3 (es) | 2008-05-01 |
| ATE378005T1 (de) | 2007-11-15 |
| EP1389950B1 (en) | 2007-11-14 |
| US20020193698A1 (en) | 2002-12-19 |
| JP4235455B2 (ja) | 2009-03-11 |
| EP1389950A1 (en) | 2004-02-25 |
| JP2009000548A (ja) | 2009-01-08 |
| JP4778544B2 (ja) | 2011-09-21 |
| DE60223527T2 (de) | 2008-12-04 |
| FI20011000A0 (fi) | 2001-05-11 |
| FI20011000A (fi) | 2002-11-12 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PC | Transfer of assignment of patent |
Owner name: AEROCRINE AB Free format text: AEROCRINE AB |
|
| MA | Patent expired |