FI102684B - Menetelmä luontaisen HIV-gp160:n tuottamiseksi - Google Patents
Menetelmä luontaisen HIV-gp160:n tuottamiseksi Download PDFInfo
- Publication number
- FI102684B FI102684B FI901879A FI901879A FI102684B FI 102684 B FI102684 B FI 102684B FI 901879 A FI901879 A FI 901879A FI 901879 A FI901879 A FI 901879A FI 102684 B FI102684 B FI 102684B
- Authority
- FI
- Finland
- Prior art keywords
- cells
- hiv
- serum
- medium
- htlv
- Prior art date
Links
- 238000000034 method Methods 0.000 title description 11
- 230000008569 process Effects 0.000 title description 2
- 241000725303 Human immunodeficiency virus Species 0.000 claims abstract description 24
- 239000012679 serum free medium Substances 0.000 claims abstract description 11
- 210000004027 cell Anatomy 0.000 claims description 61
- 239000002609 medium Substances 0.000 claims description 21
- 238000004519 manufacturing process Methods 0.000 claims description 4
- 210000001744 T-lymphocyte Anatomy 0.000 claims description 3
- 230000010261 cell growth Effects 0.000 claims description 2
- 230000001737 promoting effect Effects 0.000 claims description 2
- 108010038826 HIV Envelope Protein gp160 Proteins 0.000 claims 1
- 108090000288 Glycoproteins Proteins 0.000 abstract description 26
- 102000003886 Glycoproteins Human genes 0.000 abstract description 26
- 108090000623 proteins and genes Proteins 0.000 description 27
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- 208000031886 HIV Infections Diseases 0.000 description 8
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- OUSKVHOYPHDTIA-DBRKOABJSA-N (3s,4s,5r,6r)-3,4,5,6,7-pentahydroxyheptan-2-one Chemical compound CC(=O)[C@@H](O)[C@@H](O)[C@H](O)[C@H](O)CO OUSKVHOYPHDTIA-DBRKOABJSA-N 0.000 description 1
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- 108091003079 Bovine Serum Albumin Proteins 0.000 description 1
- 210000004366 CD4-positive T-lymphocyte Anatomy 0.000 description 1
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- 108010062580 Concanavalin A Proteins 0.000 description 1
- 238000012286 ELISA Assay Methods 0.000 description 1
- 101710121417 Envelope glycoprotein Proteins 0.000 description 1
- 108010089171 HIV Envelope Protein gp41 Proteins 0.000 description 1
- 229940033330 HIV vaccine Drugs 0.000 description 1
- 241000238631 Hexapoda Species 0.000 description 1
- 108060003951 Immunoglobulin Proteins 0.000 description 1
- 108090001061 Insulin Proteins 0.000 description 1
- 102000004877 Insulin Human genes 0.000 description 1
- 101710155913 Major envelope protein Proteins 0.000 description 1
- 241001465754 Metazoa Species 0.000 description 1
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- 230000002285 radioactive effect Effects 0.000 description 1
- 238000010188 recombinant method Methods 0.000 description 1
- 235000017557 sodium bicarbonate Nutrition 0.000 description 1
- 229910000030 sodium bicarbonate Inorganic materials 0.000 description 1
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- 239000012581 transferrin Substances 0.000 description 1
- RYFMWSXOAZQYPI-UHFFFAOYSA-K trisodium phosphate Chemical compound [Na+].[Na+].[Na+].[O-]P([O-])([O-])=O RYFMWSXOAZQYPI-UHFFFAOYSA-K 0.000 description 1
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- DGVVWUTYPXICAM-UHFFFAOYSA-N β‐Mercaptoethanol Chemical compound OCCS DGVVWUTYPXICAM-UHFFFAOYSA-N 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
- C07K14/08—RNA viruses
- C07K14/15—Retroviridae, e.g. bovine leukaemia virus, feline leukaemia virus human T-cell leukaemia-lymphoma virus
- C07K14/155—Lentiviridae, e.g. human immunodeficiency virus [HIV], visna-maedi virus or equine infectious anaemia virus
- C07K14/16—HIV-1 ; HIV-2
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
- G01N33/56983—Viruses
- G01N33/56988—HIV or HTLV
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2740/00—Reverse transcribing RNA viruses
- C12N2740/00011—Details
- C12N2740/10011—Retroviridae
- C12N2740/16011—Human Immunodeficiency Virus, HIV
- C12N2740/16111—Human Immunodeficiency Virus, HIV concerning HIV env
- C12N2740/16122—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/974—Aids related test
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Virology (AREA)
- Immunology (AREA)
- Molecular Biology (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Hematology (AREA)
- Biochemistry (AREA)
- Medicinal Chemistry (AREA)
- Biomedical Technology (AREA)
- Urology & Nephrology (AREA)
- Genetics & Genomics (AREA)
- AIDS & HIV (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biophysics (AREA)
- Gastroenterology & Hepatology (AREA)
- Tropical Medicine & Parasitology (AREA)
- General Physics & Mathematics (AREA)
- Biotechnology (AREA)
- Cell Biology (AREA)
- Microbiology (AREA)
- Pathology (AREA)
- Food Science & Technology (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicines Containing Plant Substances (AREA)
- Element Separation (AREA)
- Steroid Compounds (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Physical Vapour Deposition (AREA)
Applications Claiming Priority (6)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US23285988A | 1988-08-16 | 1988-08-16 | |
| US23285988 | 1988-08-16 | ||
| US36254889 | 1989-06-07 | ||
| US07/362,548 US5116740A (en) | 1988-08-16 | 1989-06-07 | Method for producing native hiv gp160 |
| PCT/US1989/003428 WO1990002196A1 (en) | 1988-08-16 | 1989-08-10 | Method for producing native hiv gp160 |
| US8903428 | 1989-08-10 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| FI901879A0 FI901879A0 (fi) | 1990-04-12 |
| FI102684B1 FI102684B1 (fi) | 1999-01-29 |
| FI102684B true FI102684B (fi) | 1999-01-29 |
Family
ID=26926401
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FI901879A FI102684B (fi) | 1988-08-16 | 1990-04-12 | Menetelmä luontaisen HIV-gp160:n tuottamiseksi |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US5116740A (de) |
| EP (1) | EP0394386B1 (de) |
| KR (1) | KR900702045A (de) |
| AT (1) | ATE127526T1 (de) |
| AU (1) | AU638214B2 (de) |
| DE (1) | DE68924155T2 (de) |
| DK (1) | DK175733B1 (de) |
| FI (1) | FI102684B (de) |
| HK (1) | HK1000969A1 (de) |
| WO (1) | WO1990002196A1 (de) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5254457A (en) * | 1989-01-11 | 1993-10-19 | The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services | Monoclonal antibodies and method for identifying different aids-related viruses |
| ATE125157T1 (de) * | 1990-04-03 | 1995-08-15 | Genentech Inc | Methoden und zusammensetzungen zur impfung gegen hiv. |
| US7041293B1 (en) | 1990-04-03 | 2006-05-09 | Genentech, Inc. | HIV env antibodies |
| WO1992006220A1 (en) * | 1990-10-05 | 1992-04-16 | President And Fellows Of Harvard College | Detection and isolation of ligands |
| WO1994028929A1 (en) | 1993-06-07 | 1994-12-22 | Genentech, Inc. | Hiv envelope polypeptides |
| US5736317A (en) * | 1995-03-07 | 1998-04-07 | Akzo Nobel N.V. | Human T-cell line infected with HIV-2 which secretes a protein corresponding to native HIV-2 gp160 in an extracellular medium |
| US6585979B1 (en) | 1996-07-08 | 2003-07-01 | Genentech, Inc. | HIV envelope polypeptides and immunogenic composition |
| ZA975889B (en) * | 1996-07-08 | 1998-02-23 | Genentech Inc | HIV envelope polypeptides and vaccine. |
| US20020155120A1 (en) * | 1996-07-10 | 2002-10-24 | Lowell George H. | Protein and peptide vaccines for inducing mucosal immunity |
| CN1500806B (zh) * | 2002-11-14 | 2010-05-05 | 上海科华生物工程股份有限公司 | 一种HIV－1ɡp160膜蛋白及其制备方法和应用 |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4699785A (en) * | 1984-09-18 | 1987-10-13 | The Regents Of The University Of California | Cell line producing feline leukemia virus |
| WO1990002567A1 (en) * | 1988-09-02 | 1990-03-22 | The Ohio State University Research Foundation | Virus-derived antigenic composition and its preparation and use |
-
1989
- 1989-06-07 US US07/362,548 patent/US5116740A/en not_active Expired - Lifetime
- 1989-08-10 DE DE68924155T patent/DE68924155T2/de not_active Expired - Lifetime
- 1989-08-10 AT AT89909487T patent/ATE127526T1/de not_active IP Right Cessation
- 1989-08-10 KR KR1019900700768A patent/KR900702045A/ko not_active Application Discontinuation
- 1989-08-10 WO PCT/US1989/003428 patent/WO1990002196A1/en active IP Right Grant
- 1989-08-10 AU AU40687/89A patent/AU638214B2/en not_active Expired
- 1989-08-10 EP EP89909487A patent/EP0394386B1/de not_active Expired - Lifetime
-
1990
- 1990-04-10 DK DK199000900A patent/DK175733B1/da not_active IP Right Cessation
- 1990-04-12 FI FI901879A patent/FI102684B/fi active IP Right Grant
-
1997
- 1997-12-29 HK HK97102646A patent/HK1000969A1/xx not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| AU638214B2 (en) | 1993-06-24 |
| DK175733B1 (da) | 2005-02-07 |
| HK1000969A1 (en) | 1998-05-15 |
| FI901879A0 (fi) | 1990-04-12 |
| EP0394386A4 (en) | 1991-03-13 |
| DE68924155T2 (de) | 1996-04-18 |
| US5116740A (en) | 1992-05-26 |
| KR900702045A (ko) | 1990-12-05 |
| EP0394386A1 (de) | 1990-10-31 |
| EP0394386B1 (de) | 1995-09-06 |
| WO1990002196A1 (en) | 1990-03-08 |
| ATE127526T1 (de) | 1995-09-15 |
| DE68924155D1 (de) | 1995-10-12 |
| FI102684B1 (fi) | 1999-01-29 |
| AU4068789A (en) | 1990-03-23 |
| DK90090A (da) | 1990-04-10 |
| DK90090D0 (da) | 1990-04-10 |
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Owner name: AKZO N.V. |