ES8801383A1 - Un procedimiento para purificar uromodulina a partir de orina cruda - Google Patents

Un procedimiento para purificar uromodulina a partir de orina cruda

Info

Publication number
ES8801383A1
ES8801383A1 ES556683A ES556683A ES8801383A1 ES 8801383 A1 ES8801383 A1 ES 8801383A1 ES 556683 A ES556683 A ES 556683A ES 556683 A ES556683 A ES 556683A ES 8801383 A1 ES8801383 A1 ES 8801383A1
Authority
ES
Spain
Prior art keywords
uromodulin
processes
producing
glycoprotein
isolated
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES556683A
Other languages
English (en)
Other versions
ES556683A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Biogen NV
Original Assignee
Biogen NV
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Biogen NV filed Critical Biogen NV
Publication of ES556683A0 publication Critical patent/ES556683A0/es
Publication of ES8801383A1 publication Critical patent/ES8801383A1/es
Expired legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/22—Urine; Urinary tract, e.g. kidney or bladder; Intraglomerular mesangial cells; Renal mesenchymal cells; Adrenal gland
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Abstract

PROCEDIMIENTO PARA PURIFICAR UROMODULINA A PARTIR DE ORINA CRUDA. COMPRENDE LAS OPERACIONES DE PONER EN COBTACTO LA ORINA CON UNA COLUMNA DE AFINIDAD QUE CONTIENE UNA LECTINA QUE RECONOCE MANOSA; DE LAVAR LA COLUMNA PARA SEPARAR LOS COMPONENTES DE LA ORINA NO FIJADOS A LA COLUMNA; DE ELUDIR LA UROMODULINA DE LA COLUMNA; DE DIALIZAR DE LA UROMODULINA CONTAMINANTES DE BAJO PESO MOLECULAR; DE CONCENTRAR LA UROMODULINA; Y DE ELUIR LA UROMODULINA POR CLASIFICACION POR TAMAÑOS MOLECULARES. DE APLICACION COMO AGENTE INMUNOSUPRESOR Y COMO AGENTE ANTIINFLAMATORIO.
ES556683A 1985-06-27 1986-06-25 Un procedimiento para purificar uromodulina a partir de orina cruda Expired ES8801383A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US74944285A 1985-06-27 1985-06-27

Publications (2)

Publication Number Publication Date
ES556683A0 ES556683A0 (es) 1988-01-01
ES8801383A1 true ES8801383A1 (es) 1988-01-01

Family

ID=25013780

Family Applications (1)

Application Number Title Priority Date Filing Date
ES556683A Expired ES8801383A1 (es) 1985-06-27 1986-06-25 Un procedimiento para purificar uromodulina a partir de orina cruda

Country Status (6)

Country Link
EP (1) EP0227810A4 (es)
JP (1) JPS63500592A (es)
AU (1) AU6132486A (es)
DK (1) DK105687A (es)
ES (1) ES8801383A1 (es)
WO (1) WO1987000183A1 (es)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5109116A (en) * 1989-07-24 1992-04-28 Monsanto Company Immunosuppressive glycoprotein
CA2163450A1 (en) * 1993-05-21 1994-12-08 Joseph A. Hill Embryotoxic factors
JP3839509B2 (ja) * 1995-12-14 2006-11-01 日本ケミカルリサーチ株式会社 タム−ホースフォール・グリコプロテインもしくはウロモジュリンの精製法、精製物および両者の識別法

Also Published As

Publication number Publication date
DK105687D0 (da) 1987-02-27
JPS63500592A (ja) 1988-03-03
ES556683A0 (es) 1988-01-01
EP0227810A1 (en) 1987-07-08
EP0227810A4 (en) 1987-12-01
AU6132486A (en) 1987-01-30
DK105687A (da) 1987-02-27
WO1987000183A1 (en) 1987-01-15

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