ES8801382A1 - Procedimiento para la separacion y el aislamiento del nosiheptido - Google Patents

Procedimiento para la separacion y el aislamiento del nosiheptido

Info

Publication number
ES8801382A1
ES8801382A1 ES556273A ES556273A ES8801382A1 ES 8801382 A1 ES8801382 A1 ES 8801382A1 ES 556273 A ES556273 A ES 556273A ES 556273 A ES556273 A ES 556273A ES 8801382 A1 ES8801382 A1 ES 8801382A1
Authority
ES
Spain
Prior art keywords
nosiheptide
separation
isolation
water
solvent
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES556273A
Other languages
English (en)
Other versions
ES556273A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Rhone Poulenc Sante SA
Original Assignee
Rhone Poulenc Sante SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Rhone Poulenc Sante SA filed Critical Rhone Poulenc Sante SA
Publication of ES556273A0 publication Critical patent/ES556273A0/es
Publication of ES8801382A1 publication Critical patent/ES8801382A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06139—Dipeptides with the first amino acid being heterocyclic

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Fodder In General (AREA)
  • Insulating Bodies (AREA)
  • Organic Insulating Materials (AREA)
  • Coupling Device And Connection With Printed Circuit (AREA)
  • Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
  • Flanged Joints, Insulating Joints, And Other Joints (AREA)
  • Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)
  • Formation Of Insulating Films (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Control Of Motors That Do Not Use Commutators (AREA)
  • Polymers With Sulfur, Phosphorus Or Metals In The Main Chain (AREA)

Abstract

METODO DE SEPARAR Y AISLAR NOSIHEPTIDO. CONSISTE EN MEZCLAR UN MEDIO DE CULTIVO, OBTENIDO POR CULTIVO DE UNA CEPA PRODUCTORA DE NOSIHEPTIDO PROCEDENTE DEL GENERO STREPTOMYCES, CON UN DISOLVENTE SOLUBLE EN AGUA; Y SEPARAR EL NOSIHEPTIDO A PARTIR DE LA SOLUCION OBTENIDA TRAS SEPARACION DE UNA FRACCION INSOLUBLE EN EL DISOLVENTE QUE TIENE EL MICELIO COMO CONSTITUYENTE ESENCIAL, PRECIPITANDOSE EL NOSIHEPTIDO POR ADICION PROGRESIVA DE AGUA O DE AGUA QUE CONTIENE UN ACIDO MINERAL U ORGANICO EN CANTIDAD DE 0,3 A 2 VECES EL VOLUMEN DE LA SOLUCION DE NOSIHEPTIDO, Y SIENDO LA CANTIDAD DE ACIDO TAL QUE EL PH DE LA SOLUCION ESTA COMPRENDIDO ENTRE 3 Y 7. TIENEN UTILIDAD COMO ADYUVANTES DE ALIMENTACION ANIMAL.
ES556273A 1985-06-19 1986-06-19 Procedimiento para la separacion y el aislamiento del nosiheptido Expired ES8801382A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP60133552A JPH0659226B2 (ja) 1985-06-19 1985-06-19 ノシヘプタイドの分離回収方法

Publications (2)

Publication Number Publication Date
ES556273A0 ES556273A0 (es) 1987-12-16
ES8801382A1 true ES8801382A1 (es) 1987-12-16

Family

ID=15107480

Family Applications (1)

Application Number Title Priority Date Filing Date
ES556273A Expired ES8801382A1 (es) 1985-06-19 1986-06-19 Procedimiento para la separacion y el aislamiento del nosiheptido

Country Status (8)

Country Link
US (1) US5093243A (es)
EP (1) EP0207846B1 (es)
JP (1) JPH0659226B2 (es)
AT (1) ATE66931T1 (es)
CA (1) CA1248092A (es)
DE (1) DE3681212D1 (es)
DK (1) DK164072C (es)
ES (1) ES8801382A1 (es)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106319004A (zh) * 2015-07-09 2017-01-11 牡丹江佰佳信生物科技有限公司 一种可提高那西肽产量的发酵培养基及培养方法

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6837395B2 (en) * 2002-11-22 2005-01-04 3M Innovative Properties Company Sheet dispensers and methods of making and using the same
CN103898181B (zh) * 2014-04-17 2016-05-25 河北圣雪大成制药有限责任公司 一种发酵生产那西肽的方法
CN105198958A (zh) * 2015-09-29 2015-12-30 浙江汇能动物药品有限公司 一种那西肽精粉的提取方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3155581A (en) * 1961-02-24 1964-11-03 Rhone Poulenc Sa Antibiotic and production thereof
US4384043A (en) * 1981-09-02 1983-05-17 American Cyanamid Company Process for producing the antibiotic nosiheptide
JPS6012990A (ja) * 1983-07-04 1985-01-23 Mitsubishi Chem Ind Ltd ノシヘプタイドの分離回収方法

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106319004A (zh) * 2015-07-09 2017-01-11 牡丹江佰佳信生物科技有限公司 一种可提高那西肽产量的发酵培养基及培养方法
CN106319004B (zh) * 2015-07-09 2020-10-27 牡丹江佰佳信生物科技有限公司 一种可提高那西肽产量的发酵培养基及培养方法

Also Published As

Publication number Publication date
ES556273A0 (es) 1987-12-16
DE3681212D1 (de) 1991-10-10
ATE66931T1 (de) 1991-09-15
EP0207846A3 (en) 1988-05-25
US5093243A (en) 1992-03-03
EP0207846A2 (fr) 1987-01-07
EP0207846B1 (fr) 1991-09-04
DK286586A (da) 1986-12-20
CA1248092A (fr) 1989-01-03
DK286586D0 (da) 1986-06-18
DK164072B (da) 1992-05-04
JPH0659226B2 (ja) 1994-08-10
JPS61293383A (ja) 1986-12-24
DK164072C (da) 1992-09-28

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