ES8707555A1 - Procedimiento para la determinacion inmunologica del proteoglicano sulfato de heparano - Google Patents

Procedimiento para la determinacion inmunologica del proteoglicano sulfato de heparano

Info

Publication number
ES8707555A1
ES8707555A1 ES557216A ES557216A ES8707555A1 ES 8707555 A1 ES8707555 A1 ES 8707555A1 ES 557216 A ES557216 A ES 557216A ES 557216 A ES557216 A ES 557216A ES 8707555 A1 ES8707555 A1 ES 8707555A1
Authority
ES
Spain
Prior art keywords
heparan sulphate
sulphate proteoglycan
purification
extraction
immunological determination
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES557216A
Other languages
English (en)
Other versions
ES557216A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Hoechst AG
Max Planck Gesellschaft zur Foerderung der Wissenschaften eV
Original Assignee
Hoechst AG
Max Planck Gesellschaft zur Foerderung der Wissenschaften eV
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst AG, Max Planck Gesellschaft zur Foerderung der Wissenschaften eV filed Critical Hoechst AG
Publication of ES557216A0 publication Critical patent/ES557216A0/es
Publication of ES8707555A1 publication Critical patent/ES8707555A1/es
Expired legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6887—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids from muscle, cartilage or connective tissue
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4725—Proteoglycans, e.g. aggreccan

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Immunology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Hematology (AREA)
  • Medicinal Chemistry (AREA)
  • Urology & Nephrology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Organic Chemistry (AREA)
  • Biotechnology (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Cell Biology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Microbiology (AREA)
  • Toxicology (AREA)
  • Food Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Analytical Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Peptides Or Proteins (AREA)
  • Cleaning Implements For Floors, Carpets, Furniture, Walls, And The Like (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Separation Using Semi-Permeable Membranes (AREA)

Abstract

METODO DE DETERMINACION INMUNOLOGICA DEL PROTEOGLICANO SULFATO DE HEPARANO. COMPRENDE: A) HACER REACCIONAR LOS ANTICUERPOS CON UN EXCESO DE ANTIGENOS MARCADOS, PARA FORMAR UN COMPLEJO DE ANTIGENO-ANTICUERPO Y UN MATERIAL SOBRENADANTE; B) SEPARAR EL COMPLEJO ANTIGENO ANTICUERPO; Y C) DETERMINAR LA CANTIDAD DE ANTIGENO MARCADO EN EL COMPLEJO ANTIGENO-ANTICUERPO, PARA FORMAR EL ANTIGENO PROTEOGLICANO SULFATO DE HEPARANO. SE UTILIZA PARA TRATAR LA DIABETES MELLITUS Y LAS DIABETES TARDIAS COMO NEFROPATIA.
ES557216A 1985-03-28 1986-11-21 Procedimiento para la determinacion inmunologica del proteoglicano sulfato de heparano Expired ES8707555A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19853511199 DE3511199A1 (de) 1985-03-28 1985-03-28 Verfahren zur immunologischen bestimmung von heparansulfat-proteoglykan, verfahren zur herstellung bzw. reinigung von dafuer geeignetem heparansulfat-proteoglykan aus basalmembran-haltigen geweben

Publications (2)

Publication Number Publication Date
ES557216A0 ES557216A0 (es) 1987-08-01
ES8707555A1 true ES8707555A1 (es) 1987-08-01

Family

ID=6266532

Family Applications (3)

Application Number Title Priority Date Filing Date
ES553462A Expired ES8705898A1 (es) 1985-03-28 1986-03-26 Procedimiento para preparar proteglicano sulfato de heparano de baja densidad.
ES557217A Expired ES8802165A1 (es) 1985-03-28 1986-11-21 Procedimiento para producir sueros muy especificos con anticuerpos frente a proteoglicano sulfato de heparano
ES557216A Expired ES8707555A1 (es) 1985-03-28 1986-11-21 Procedimiento para la determinacion inmunologica del proteoglicano sulfato de heparano

Family Applications Before (2)

Application Number Title Priority Date Filing Date
ES553462A Expired ES8705898A1 (es) 1985-03-28 1986-03-26 Procedimiento para preparar proteglicano sulfato de heparano de baja densidad.
ES557217A Expired ES8802165A1 (es) 1985-03-28 1986-11-21 Procedimiento para producir sueros muy especificos con anticuerpos frente a proteoglicano sulfato de heparano

Country Status (8)

Country Link
EP (1) EP0198259B1 (es)
JP (1) JPS61229900A (es)
AT (1) ATE77054T1 (es)
DE (2) DE3511199A1 (es)
DK (1) DK142986A (es)
ES (3) ES8705898A1 (es)
GR (1) GR860808B (es)
PT (1) PT82300B (es)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3639561A1 (de) * 1986-11-20 1988-06-01 Baumann Hanno Verfahren zur herstellung von nicht-thrombogenen substraten
DE3708198A1 (de) * 1987-03-13 1988-09-22 Hoechst Ag Verfahren zur isolierung von basalmembranproteinen aus menschlichen und tierischen geweben
ES2085346T3 (es) * 1988-12-12 1996-06-01 Bard Diagnostic Sciences Inc Deteccion de componentes de la membrana basal como diagnostico del cancer y de otras enfermedades.
KR0162670B1 (ko) * 1991-01-15 1999-05-01 마르쿠 잘카넨 세포의 악성 전형을 나타내기 위한 조직 및 체액과 같은 생물학적 물질에서의 신데칸 내용물의 검출

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2923583A1 (de) * 1979-06-11 1980-12-18 Max Planck Gesellschaft Verfahren zur immunologischen bestimmung von basalmembranmaterial und hierfuer geeignete neue basalmembranfragmente

Also Published As

Publication number Publication date
DE3511199A1 (de) 1986-10-02
EP0198259B1 (de) 1992-06-10
ES8802165A1 (es) 1988-04-01
ES557216A0 (es) 1987-08-01
ES8705898A1 (es) 1987-05-16
DK142986A (da) 1986-09-29
JPS61229900A (ja) 1986-10-14
ATE77054T1 (de) 1992-06-15
GR860808B (en) 1986-07-25
PT82300A (de) 1986-04-01
ES553462A0 (es) 1987-05-16
DE3685603D1 (de) 1992-07-16
DK142986D0 (da) 1986-03-26
ES557217A0 (es) 1988-04-01
EP0198259A1 (de) 1986-10-22
PT82300B (pt) 1988-07-29

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Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 19970505