ES8706719A1 - Procedimiento para preparar un derivado de trilostano - Google Patents
Procedimiento para preparar un derivado de trilostanoInfo
- Publication number
- ES8706719A1 ES8706719A1 ES540686A ES540686A ES8706719A1 ES 8706719 A1 ES8706719 A1 ES 8706719A1 ES 540686 A ES540686 A ES 540686A ES 540686 A ES540686 A ES 540686A ES 8706719 A1 ES8706719 A1 ES 8706719A1
- Authority
- ES
- Spain
- Prior art keywords
- compound
- chem
- therapy
- formula
- treatment
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J71/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
- C07J71/0036—Nitrogen-containing hetero ring
- C07J71/0057—Nitrogen and oxygen
- C07J71/0063—Nitrogen and oxygen at position 2(3)
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J71/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
- C07J71/0005—Oxygen-containing hetero ring
- C07J71/001—Oxiranes
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Steroid Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Saccharide Compounds (AREA)
- Cephalosporin Compounds (AREA)
Abstract
PROCEDIMIENTO PARA PREPARAR UN DERIVADO DE TRILOSTANO. COMPRENDE: A) TRATAR UNA SUSPENSION DE COMPUESTO DE FORMULA (II) CON UN ALCOXIDO DE METAL ALCALINO, ENTRE 5 Y 50GC, PARA ABRIR EL ANILLO ISOXAZOL DE (II) Y OBTENER UN COMPUESTO DE FORMULA (I); Y B) SECAR EL COMPUESTO DE FORMULA (I) POR SUCCION. SE UTILIZA COMO INHIBIDOR ESTEROIDOGENESICO ADRENAL EN LA TERAPIA HUMANA Y ANIMAL. *FORMULA*
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB848404980A GB8404980D0 (en) | 1984-02-25 | 1984-02-25 | Steroid compound |
Publications (2)
Publication Number | Publication Date |
---|---|
ES540686A0 ES540686A0 (es) | 1987-06-16 |
ES8706719A1 true ES8706719A1 (es) | 1987-06-16 |
Family
ID=10557191
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES540686A Expired ES8706719A1 (es) | 1984-02-25 | 1985-02-25 | Procedimiento para preparar un derivado de trilostano |
Country Status (13)
Country | Link |
---|---|
EP (1) | EP0154476B1 (es) |
AT (1) | ATE52788T1 (es) |
BE (1) | BE901813A (es) |
DE (1) | DE3577710D1 (es) |
DK (1) | DK80485A (es) |
ES (1) | ES8706719A1 (es) |
FI (1) | FI850759L (es) |
GB (1) | GB8404980D0 (es) |
GR (1) | GR850486B (es) |
IT (1) | IT1184890B (es) |
LU (1) | LU85786A1 (es) |
NO (1) | NO160851C (es) |
PT (1) | PT80008B (es) |
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB2345851B (en) * | 2000-01-18 | 2004-05-26 | Gavin Paul Vinson | A combination of trilostane or keto-trilostane and an anti-oestrogen for the treatment of an oestrogen-dependent cancer or tumour |
GB2375958B (en) * | 2001-04-09 | 2005-03-02 | George Margetts | The use of steroids to lower the levels of cortisol |
GB2416138A (en) * | 2004-07-15 | 2006-01-18 | Stegram Pharmaceuticals Ltd | Chromatographic separation of trilostane mixture |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB1123770A (en) * | 1966-11-15 | 1968-08-14 | Sterling Drug Inc | 2-cyano-3-oxo-steroids |
US4160027A (en) * | 1977-12-20 | 1979-07-03 | Sterling Drug Inc. | Steroid cyanoketones and intermediates |
-
1984
- 1984-02-25 GB GB848404980A patent/GB8404980D0/en active Pending
-
1985
- 1985-02-22 DK DK80485A patent/DK80485A/da not_active Application Discontinuation
- 1985-02-25 PT PT80008A patent/PT80008B/pt not_active IP Right Cessation
- 1985-02-25 AT AT85301239T patent/ATE52788T1/de active
- 1985-02-25 IT IT67191/85A patent/IT1184890B/it active
- 1985-02-25 EP EP85301239A patent/EP0154476B1/en not_active Expired - Lifetime
- 1985-02-25 ES ES540686A patent/ES8706719A1/es not_active Expired
- 1985-02-25 FI FI850759A patent/FI850759L/fi not_active Application Discontinuation
- 1985-02-25 LU LU85786A patent/LU85786A1/fr unknown
- 1985-02-25 NO NO850753A patent/NO160851C/no unknown
- 1985-02-25 BE BE0/214563A patent/BE901813A/fr unknown
- 1985-02-25 DE DE8585301239T patent/DE3577710D1/de not_active Expired - Fee Related
- 1985-02-26 GR GR850486A patent/GR850486B/el unknown
Also Published As
Publication number | Publication date |
---|---|
IT8567191A0 (it) | 1985-02-25 |
GB8404980D0 (en) | 1984-03-28 |
IT1184890B (it) | 1987-10-28 |
EP0154476A2 (en) | 1985-09-11 |
FI850759A0 (fi) | 1985-02-25 |
LU85786A1 (fr) | 1985-12-11 |
IT8567191A1 (it) | 1986-08-25 |
DE3577710D1 (de) | 1990-06-21 |
ATE52788T1 (de) | 1990-06-15 |
NO850753L (no) | 1985-08-26 |
FI850759L (fi) | 1985-08-26 |
ES540686A0 (es) | 1987-06-16 |
BE901813A (fr) | 1985-08-26 |
GR850486B (es) | 1985-06-26 |
EP0154476A3 (en) | 1986-05-14 |
PT80008A (en) | 1985-03-01 |
NO160851B (no) | 1989-02-27 |
NO160851C (no) | 1989-06-07 |
PT80008B (en) | 1987-01-13 |
DK80485D0 (da) | 1985-02-22 |
EP0154476B1 (en) | 1990-05-16 |
DK80485A (da) | 1985-08-26 |
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