ES8706209A1 - Un procedimiento para la preparacion de un proteina envolvente de un virus de sindrome de inmunodeficiencia adquirida - Google Patents

Un procedimiento para la preparacion de un proteina envolvente de un virus de sindrome de inmunodeficiencia adquirida

Info

Publication number
ES8706209A1
ES8706209A1 ES554155A ES554155A ES8706209A1 ES 8706209 A1 ES8706209 A1 ES 8706209A1 ES 554155 A ES554155 A ES 554155A ES 554155 A ES554155 A ES 554155A ES 8706209 A1 ES8706209 A1 ES 8706209A1
Authority
ES
Spain
Prior art keywords
aids
envelope protein
recombinant
immune deficiency
deficiency syndrome
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES554155A
Other languages
English (en)
Other versions
ES554155A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
F Hoffmann La Roche AG
US Department of Health and Human Services
US Government
Original Assignee
F Hoffmann La Roche AG
US Department of Health and Human Services
US Government
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=24912812&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ES8706209(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by F Hoffmann La Roche AG, US Department of Health and Human Services, US Government filed Critical F Hoffmann La Roche AG
Publication of ES8706209A1 publication Critical patent/ES8706209A1/es
Publication of ES554155A0 publication Critical patent/ES554155A0/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/70—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving virus or bacteriophage
    • C12Q1/701—Specific hybridization probes
    • C12Q1/702—Specific hybridization probes for retroviruses
    • C12Q1/703—Viruses associated with AIDS
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2740/00—Reverse transcribing RNA viruses
    • C12N2740/00011—Details
    • C12N2740/10011—Retroviridae
    • C12N2740/16011—Human Immunodeficiency Virus, HIV
    • C12N2740/16111—Human Immunodeficiency Virus, HIV concerning HIV env
    • C12N2740/16122—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Virology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Analytical Chemistry (AREA)
  • Biotechnology (AREA)
  • Physics & Mathematics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Medicinal Chemistry (AREA)
  • AIDS & HIV (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

PROCEDIMIENTO PARA PREPARAR UNA PROTEINA ENVOLVENTE DE UNOS VIRUS DE SINDROME DE INMUNODEFICIENCIA ADQUIRIDA (SIDA). COMPRENDE: TRANSFORMAR UNA CELULA HUESPED CON UN VECTOR DE EXPRESION; B) CULTIVAR LA CELULA HUESPED TRANSFORMADA PARA EXPRESAR LA PROTEINA ENVOLVENTE DE UN VIRUS DE SIDA; C) EXTRAER Y AISLAR A LA PROTEINA ENVOLVENTE EN LA CELULA HUESPED. LA CELULA HUESPED ES UNA BACTERIA E. COLI Y EL VECTOR DE EXPRESION TIENE UN GEN QUE CODIFICA UNA PROTEINA ENVOLVENTE DE UN VIRUS DE SIDA DE CORRIENTE ABAJO DE UNA SECUENCIA PROMOTORA QUE FACULTA LA TRANSCRIPCION, REDUCCION Y EXPRESION DE LA PROTEINA ENVOLVENTE EN LA CELULA HUESPED. SE UTILIZA PARA COMBATIR EL SIDA.
ES554155A 1985-04-19 1986-04-18 Un procedimiento para la preparacion de un proteina envolvente de un virus de sindrome de inmunodeficiencia adquirida Expired ES8706209A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US72502185A 1985-04-19 1985-04-19

Publications (2)

Publication Number Publication Date
ES8706209A1 true ES8706209A1 (es) 1987-06-01
ES554155A0 ES554155A0 (es) 1987-06-01

Family

ID=24912812

Family Applications (1)

Application Number Title Priority Date Filing Date
ES554155A Expired ES8706209A1 (es) 1985-04-19 1986-04-18 Un procedimiento para la preparacion de un proteina envolvente de un virus de sindrome de inmunodeficiencia adquirida

Country Status (12)

Country Link
US (1) US6077935A (es)
EP (1) EP0199301B2 (es)
JP (1) JPS6212799A (es)
AT (1) ATE99330T1 (es)
AU (1) AU595511B2 (es)
CA (1) CA1341410C (es)
DE (1) DE3689447T2 (es)
DK (1) DK171119B1 (es)
ES (1) ES8706209A1 (es)
FI (1) FI861626A (es)
NO (1) NO861546L (es)
NZ (1) NZ215867A (es)

Families Citing this family (48)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7232654B1 (en) 1983-09-15 2007-06-19 Institut Pasteur DNA sequence of the LTR region of human immunodeficiency virus type 1 (HIV-1)
GB8429099D0 (en) 1984-11-16 1984-12-27 Pasteur Institut Closed dna sequences
GB8423659D0 (en) 1984-09-19 1984-10-24 Pasteur Institut Cloned dna sequences
US7205102B1 (en) 1983-09-15 2007-04-17 Institut Pasteur Cloned DNA sequences related to the genomic RNA of lymphadenopathy-associated virus (LAV) and proteins encoded by said LAV genomic RNA
US7351412B1 (en) 1983-12-05 2008-04-01 Institut Pasteur Cloned DNA sequences related to the genomic RNA of lymphadenopathy-associated-virus (LAV) and proteins encoded by said LAV genomic RNA
US5980900A (en) * 1984-10-18 1999-11-09 Institut Pasteur And Centre National De La Recherche Scientifique Amino acid DNA sequences related to genomic RNA of human immunodeficiency virus (HIV-1)
US7045130B1 (en) 1984-10-18 2006-05-16 Institut Pasteur Antibodies against antigens of human immunodeficiency virus (HIV-1)
US5705612A (en) * 1984-10-18 1998-01-06 Institut Pasteur And Centre National De La Recherche Scientifique NEF peptide encoded by human immunodefiency virus type 1 (HIV-1)
US6894152B1 (en) 1984-11-16 2005-05-17 Institut Pasteur Cloned DNA sequences related to the genomic RNA of lymphadenopathy-associated-virus (LAV) and proteins encoded by said LAV genomic RNA
WO1986003224A1 (en) * 1984-11-29 1986-06-05 Scripps Clinic And Research Foundation Polypeptides and antibodies related to deglycosylated viral glycoproteins
IE64785B1 (en) * 1985-04-08 1995-09-06 Genetic Systems Corp Expression of immunologically reactive viral proteins
NZ217645A (en) * 1985-09-25 1991-11-26 Oncogen Recombinant viruses expressing lav/htlv-iii related epitopes and vaccine formulations
FR2593519B1 (fr) * 1985-09-25 1994-01-07 Oncogen Vaccin contre le syndrome immunodeficitaire acquis et intermediaires pour la preparation de ce vaccin
US4734362A (en) * 1986-02-03 1988-03-29 Cambridge Bioscience Corporation Process for purifying recombinant proteins, and products thereof
US4925784A (en) * 1986-04-04 1990-05-15 Hoffmann-La Roche Inc. Expression and purification of an HTLV-III gag/env gene protein
US5017688A (en) * 1986-06-12 1991-05-21 Biogen, Inc. Peptides involved in the pathogenesis of HIV infection
US4943627A (en) * 1986-06-12 1990-07-24 Biogen, Inc. Peptides involved in the pathogenesis of HIV infection
US5087557A (en) * 1986-06-23 1992-02-11 Genetic Systems Corporation Human monoclonal antibody to lymphadenopathy-associated virus
EP0525828A3 (en) * 1986-08-01 1993-02-24 Repligen Corporation Recombinant polypeptides and their uses, including assay for aids virus
US5166050A (en) * 1986-08-20 1992-11-24 Bristol-Myers Squibb Company Monoclonal antibodies and peptides useful in treating and diagnosing HIV infections
NZ221440A (en) * 1986-08-20 1991-11-26 Genetic Systems Corp Composition containing monoclonal antibodies/peptides useful in treating and diagnosing hiv infections
FR2610632B1 (fr) * 1987-02-11 1990-12-21 Pasteur Institut Peptides caracteristiques des retrovirus d'immunodeficience humaine (virus hiv) leurs applications au diagnostic des infections dues a certains de ces virus et, le cas echeant, a la vaccination contre le sida
WO1988005440A1 (fr) * 1987-01-16 1988-07-28 Institut Pasteur Peptides ayant des proprietes immunologiques 2-hiv-2
US4861707A (en) * 1987-02-02 1989-08-29 E. I. Du Pont De Nemours And Company Human immunodeficiency virus antigen
CA1341277C (en) * 1987-03-16 2001-07-31 Roland Keith Mcgready Anti-paratopic antibody and a method of its manufacture
US4921787A (en) * 1987-05-01 1990-05-01 Cambridge Bioscience Corporation Detection of antibodies to human immunodeficiency virus by agglutination of antigen coated latex
FR2615623B1 (fr) * 1987-05-22 1992-06-19 Transgene Sa Test de diagnostic du sida base sur la mise en evidence d'une diversite de la reponse isotypique, vaccins et serotherapies
US6657050B1 (en) 1987-05-29 2003-12-02 Tanox, Inc. Chimeric viral-neutralizing immunoglobulins
US5834599A (en) * 1987-05-29 1998-11-10 Tanox Biosystems, Inc. Immunoconjugates which neutralize HIV-1 infection
US5981278A (en) * 1987-05-29 1999-11-09 Tanox, Inc. Chimeric monoclonal antibodies which neutralize HIV-1 infection and their applications in therapy and prevention for AIDS
IL86675A (en) * 1987-06-10 1993-04-04 Immune Response Corp Inc Immunogen containing non- infectious hiv particles and pharmaceutical compositions containing the same
US5256767A (en) * 1987-06-10 1993-10-26 The Immune Response Corporation Retroviral antigens
EP0311228A3 (en) * 1987-10-09 1990-05-02 Repligen Corporation Recombinant polypeptides and their uses, including assay for aids virus
NO881501L (no) * 1987-10-09 1989-04-10 Repligen Corp Rekombinante htlv-111-proteiner og anvendelser av disse.
US5254458A (en) * 1987-10-30 1993-10-19 Abbott Laboratories Immunoassays using antigens produced in heterologous organisms
US5763160A (en) * 1988-02-12 1998-06-09 United Biomedical, Inc. Synthetic peptides and process of using same for the detection of antibodies to human immunodeficiency virus (HIV) gp120 envelope protein, diagnosis of AIDS and pre-AIDS conditions and as vaccines
EP0330359A3 (en) * 1988-02-25 1991-06-05 Bio-Rad Laboratories, Inc. Composition useful in the diagnosis and treating of hiv-1 infection
FR2635532B1 (fr) * 1988-07-29 1992-05-22 Pasteur Institut Particules hbsag recombinantes hybrides : caracteristiques morphologiques de l'antigene hbsag contenant 1 sequence immunogene induisant des anticorps neutralisants diriges contre hiv ou susceptible d'etre reconnue par de tels anticorps; sequences nucleotidiques codant pour de telles particules; vaccins les contenant
CA2003383A1 (en) * 1988-11-23 1990-05-23 Sushil G. Devare Synthetic dna derived recombinant hiv antigens
FR2640877A1 (es) * 1988-12-06 1990-06-29 Centre Nat Rech Scient
DE4405810A1 (de) 1994-02-23 1995-08-24 Behringwerke Ag Von einem Retrovirus aus der HIV-Gruppe abgeleitete Peptide und deren Verwendung
EP1141313A2 (en) 1998-12-31 2001-10-10 Chiron Corporation Improved expression of hiv polypeptides and production of virus-like particles
EP1141314A2 (en) 1998-12-31 2001-10-10 Chiron Corporation Polynucleotides encoding antigenic hiv type c polypeptides, polypeptides and uses thereof
ES2299276T3 (es) 1998-12-31 2008-05-16 Novartis Vaccines And Diagnostics, Inc. Polipeptidos env del vih modificados.
US7935805B1 (en) 1998-12-31 2011-05-03 Novartis Vaccines & Diagnostics, Inc Polynucleotides encoding antigenic HIV Type C polypeptides, polypeptides and uses thereof
CA2452015C (en) 2001-07-05 2012-07-03 Chiron Corporation Polynucleotides encoding antigenic hiv type c polypeptides, polypeptides and uses thereof
AU2002316578A1 (en) 2001-08-31 2003-03-18 Chiron Corporation Polynucleotides encoding antigenic hiv type b polypeptides, polypeptides and uses thereof
US20030170614A1 (en) 2001-08-31 2003-09-11 Megede Jan Zur Polynucleotides encoding antigenic HIV type B polypeptides, polypeptides and uses thereof

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4237224A (en) * 1974-11-04 1980-12-02 Board Of Trustees Of The Leland Stanford Jr. University Process for producing biologically functional molecular chimeras
DE2814039C3 (de) * 1978-03-31 1981-02-19 Gesellschaft Fuer Biotechnologische Forschung Mbh (Gbf), 3300 Braunschweig Verfahren zur Herstellung von Hybrid-Bakterien
US4743678A (en) * 1983-04-27 1988-05-10 President And Fellows Of Harvard College Method and products for detection of human T cell leukemia virus
WO1984004327A1 (en) * 1983-04-27 1984-11-08 Harvard College Method and products for detection of human t cell leukemia virus
EP0152030A3 (en) * 1984-02-03 1986-08-13 Juridical Foundation Japanese Foundation for Cancer Research Adult t cell leukemia virus antigen polypeptide
US4520113A (en) * 1984-04-23 1985-05-28 The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services Serological detection of antibodies to HTLV-III in sera of patients with AIDS and pre-AIDS conditions
IL76082A (en) * 1984-08-22 1991-07-18 Us Health Molecular clones of the genome of htlv-iii and a process for the preparation thereof
DE3588248T2 (de) * 1984-10-18 2004-07-01 Institut Pasteur LAV-Antigene und -Peptide
CA1341482C (en) * 1984-10-31 2005-05-10 Paul A. Luciw Process for preparing fragments of aids-associated retroviruses
US4725669A (en) * 1984-11-09 1988-02-16 President And Fellows Of Harvard College Assay for detecting infection by human T-cell lymphotropic virus-III
AU600658B2 (en) * 1984-12-24 1990-08-23 Genentech Inc. Molecularly cloned acquired immunodeficiency syndrome polypeptides and their methods of use
IE64785B1 (en) * 1985-04-08 1995-09-06 Genetic Systems Corp Expression of immunologically reactive viral proteins
US4629783A (en) * 1985-04-29 1986-12-16 Genetic Systems Corporation Synthetic antigen for the detection of AIDS-related disease

Also Published As

Publication number Publication date
DK177286A (da) 1986-10-20
EP0199301A1 (en) 1986-10-29
DE3689447D1 (de) 1994-02-10
NZ215867A (en) 1989-10-27
ES554155A0 (es) 1987-06-01
EP0199301B1 (en) 1993-12-29
DK177286D0 (da) 1986-04-17
FI861626A (fi) 1986-10-20
ATE99330T1 (de) 1994-01-15
AU5636386A (en) 1986-10-23
NO861546L (no) 1986-10-20
JPS6212799A (ja) 1987-01-21
EP0199301B2 (en) 1997-07-09
US6077935A (en) 2000-06-20
DE3689447T2 (de) 1994-04-28
FI861626A0 (fi) 1986-04-17
DK171119B1 (da) 1996-06-17
CA1341410C (en) 2002-12-17
AU595511B2 (en) 1990-04-05

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Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 20100623