ES8705758A1 - Metodo de preparacion de tabletas por compresion directa. - Google Patents

Metodo de preparacion de tabletas por compresion directa.

Info

Publication number
ES8705758A1
ES8705758A1 ES551081A ES551081A ES8705758A1 ES 8705758 A1 ES8705758 A1 ES 8705758A1 ES 551081 A ES551081 A ES 551081A ES 551081 A ES551081 A ES 551081A ES 8705758 A1 ES8705758 A1 ES 8705758A1
Authority
ES
Spain
Prior art keywords
carboxylic acid
formulation
quinoline carboxylic
acid tablet
tablet
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES551081A
Other languages
English (en)
Other versions
ES551081A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck and Co Inc
Original Assignee
Merck and Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck and Co Inc filed Critical Merck and Co Inc
Publication of ES551081A0 publication Critical patent/ES551081A0/es
Publication of ES8705758A1 publication Critical patent/ES8705758A1/es
Expired legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

METODO PARA PREPARAR TABLETAS POR COMPRESION DIRECTA. COMPRENDE: A) MEZCLAR EN SECO UN AGENTE ANTIBACTERIANO CON DILUYENTES INERTES; B) COMPRIMIR LA MEZCLA PARA FORMAR UNA TABLETA; Y C) RECUBRIR LA TABLETA CON UN FORMADOR DE PELICULA. EL AGENTE ANTIBACTERIANO ES ACIDO QUINOLINCARBOXILICO (NORFLOXACIN); LOS DILUYENTES ESTAN FORMADOS POR UNA MEZCLA DEL DISGREGANTE COMO CROSCARMELOSA SODICA, CARGA/AGLOMERANTE COMO CELULOSA MICROCRISTALINA Y LUBRICANTE COMO ESTEREATO MAGNESICO Y EL FORMADOR DE PELICULA ES CELULOSA MODIFICADA. SE UTILIZAN COMO ANTIBACTERIANOS.
ES551081A 1985-01-22 1986-01-21 Metodo de preparacion de tabletas por compresion directa. Expired ES8705758A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/693,071 US4639458A (en) 1985-01-22 1985-01-22 Tablet and formulation

Publications (2)

Publication Number Publication Date
ES551081A0 ES551081A0 (es) 1987-05-16
ES8705758A1 true ES8705758A1 (es) 1987-05-16

Family

ID=24783194

Family Applications (1)

Application Number Title Priority Date Filing Date
ES551081A Expired ES8705758A1 (es) 1985-01-22 1986-01-21 Metodo de preparacion de tabletas por compresion directa.

Country Status (9)

Country Link
US (1) US4639458A (es)
EP (1) EP0189114B1 (es)
JP (1) JPH0784386B2 (es)
CA (1) CA1273877A (es)
DE (1) DE3680796D1 (es)
DK (1) DK28786A (es)
ES (1) ES8705758A1 (es)
LV (1) LV5722B4 (es)
PT (1) PT81836B (es)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4850993A (en) * 1986-12-22 1989-07-25 Miles Laboratories, Inc. Blood bag system incorporating quinolone carboxylic, acid derivatives
GB2209669B (en) * 1987-09-11 1992-02-12 Squibb & Sons Inc Pharmaceutical composition containing high drug load and method for preparing same
NZ226696A (en) * 1987-11-02 1991-10-25 Merck & Co Inc Tablet composition comprising a phthalazine acetic acid derivative as the active ingredient present in from 83-88 wt%
FR2638971B1 (fr) * 1988-11-15 1993-01-08 Vacher Dominique Comprime a delitement et/ou dissolution instantane
ATE108649T1 (de) * 1990-02-14 1994-08-15 Takeda Chemical Industries Ltd Brausemischung, deren herstellung sowie verwendung.
US5225201A (en) * 1991-08-23 1993-07-06 Minnesota Mining And Manufacturing Company Salsalate tablet
DE4200821A1 (de) * 1992-01-15 1993-07-22 Bayer Ag Geschmacksmaskierte pharmazeutische mittel
FR2711524B1 (fr) * 1993-10-21 1995-11-24 Rhone Dpc Europ Procédé de préparation de compositions orales contenant des quinolones.
US20010007863A1 (en) 1998-06-18 2001-07-12 Merck & Co., Inc. Wet granulation formulation for bisphosphonic acids
AU4353996A (en) * 1994-12-14 1996-07-03 Bioglan Ireland (R & D) Limited Pharmaceutical tablet formulations for direct compression
CN1090935C (zh) * 1995-02-28 2002-09-18 阿温蒂斯药物公司 哌啶子基烷醇化合物的药物组合物
US6488961B1 (en) 1996-09-20 2002-12-03 Ethypharm, Inc. Effervescent granules and methods for their preparation
US6649186B1 (en) 1996-09-20 2003-11-18 Ethypharm Effervescent granules and methods for their preparation
NZ501248A (en) * 1997-08-26 2001-06-29 Aventis Pharma Inc Pharmaceutical composition for combination of piperidinoalkanol-decongestant
IN186245B (es) 1997-09-19 2001-07-14 Ranbaxy Lab Ltd
DE10031043A1 (de) 2000-06-26 2002-02-14 Bayer Ag Retardzubereitungen von Chinolonantibiotika und Verfahren zu ihrer Herstellung
CA2479350A1 (en) * 2002-03-15 2003-09-25 Cypress Bioscience, Inc. Ne and 5-ht reuptake inhibitors for treating visceral pain syndromes
GB0209265D0 (en) 2002-04-23 2002-06-05 Novartis Ag Organic compounds
ES2297067T3 (es) * 2003-03-19 2008-05-01 The Jordanian Pharmaceutical Manufacturing Co. Ltd. Composiciones farmaceuticas no higroscopicas que contienen acidos quinolinacarboxilicos de hidratados.
BR112014012994A2 (pt) * 2011-11-30 2017-06-13 Toyama Chemical Co Ltd tablete contendo hidrato de metanossulfonato do ácido 1-ciclopropil-8-(difluorometóxi)-7-[(1r)-1-metil-2,3-diidro-1h-isoindol-5-il]-4-oxo-1, 4-diidroquinolina-3-carboxílico
CN107115312A (zh) * 2017-05-17 2017-09-01 湖南新汇制药股份有限公司 一种诺氟沙星片及其制备方法
CN107669645A (zh) * 2017-10-31 2018-02-09 瑞阳制药有限公司 盐酸环丙沙星片的制备方法

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US29077A (en) * 1860-07-10 Cabpet-sweepee
US4072535A (en) * 1970-12-28 1978-02-07 A. E. Staley Manufacturing Company Precompacted-starch binder-disintegrant-filler material for direct compression tablets and dry dosage capsules
USRE29077E (en) 1972-12-06 1976-12-14 Ives Laboratories Inc. Tablet formulation
US3873694A (en) * 1973-09-27 1975-03-25 Cpc International Inc Direct compression tabletting composition and pharmaceutical tablets produced therefrom
US4097606A (en) * 1975-10-08 1978-06-27 Bristol-Myers Company APAP Tablet containing an alkali metal carboxymethylated starch and processes for manufacturing same
DE3013839A1 (de) * 1979-04-13 1980-10-30 Freunt Ind Co Ltd Verfahren zur herstellung einer aktivierten pharmazeutischen zusammensetzung
US4293539A (en) * 1979-09-12 1981-10-06 Eli Lilly And Company Controlled release formulations and method of treatment
JPS57134482A (en) * 1981-02-13 1982-08-19 Dainippon Pharmaceut Co Ltd 1-ethyl-6-fluoro-1,4-dihydro-4-oxo-7-(1-piperazinyl)-1,8- naphthyridine-3-carboxylic acid-3/2 hydrate and its preparation
US4370313A (en) * 1981-10-26 1983-01-25 Eaton Laboratories, Inc. Nitrofurantoin dosage form
US4369172A (en) * 1981-12-18 1983-01-18 Forest Laboratories Inc. Prolonged release therapeutic compositions based on hydroxypropylmethylcellulose
US4530928A (en) * 1982-01-13 1985-07-23 Merck & Co., Inc. Quinoline carboxylic acid complexes with guanidinium carbonate
US4440740A (en) * 1982-04-26 1984-04-03 Merck & Co., Inc. α-Keto aldehydes as enhancing agents of gastro-intestinal drug absorption
US4522818A (en) * 1982-10-14 1985-06-11 Pennwalt Corporation Diuretic/antihypertensive compositions
US4517179A (en) * 1983-04-29 1985-05-14 Pennwalt Corporation Rapid dissolving, uniform drug compositions and their preparation
US4478822A (en) * 1983-05-16 1984-10-23 Merck & Co., Inc. Drug delivery system utilizing thermosetting gels

Also Published As

Publication number Publication date
LV5722A4 (lv) 1996-02-20
US4639458A (en) 1987-01-27
ES551081A0 (es) 1987-05-16
EP0189114A2 (en) 1986-07-30
EP0189114A3 (en) 1987-08-26
JPH0784386B2 (ja) 1995-09-13
DE3680796D1 (de) 1991-09-19
PT81836A (en) 1986-02-01
PT81836B (pt) 1987-11-30
DK28786A (da) 1986-07-23
DK28786D0 (da) 1986-01-21
CA1273877A (en) 1990-09-11
LV5722B4 (lv) 1996-06-20
JPS61167618A (ja) 1986-07-29
EP0189114B1 (en) 1991-08-14

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Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 20070313