ES8701724A1 - New tetra:hydro-3,5-pyridine-di:carboxylic acid derivs. - Google Patents

New tetra:hydro-3,5-pyridine-di:carboxylic acid derivs.

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Publication number
ES8701724A1
ES8701724A1 ES531940A ES531940A ES8701724A1 ES 8701724 A1 ES8701724 A1 ES 8701724A1 ES 531940 A ES531940 A ES 531940A ES 531940 A ES531940 A ES 531940A ES 8701724 A1 ES8701724 A1 ES 8701724A1
Authority
ES
Spain
Prior art keywords
alkyl
substd
opt
halogen
pyridine
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES531940A
Other languages
Spanish (es)
Other versions
ES531940A0 (en
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Fisons Ltd
Original Assignee
Fisons Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB838311520A external-priority patent/GB8311520D0/en
Priority claimed from GB838311521A external-priority patent/GB8311521D0/en
Priority claimed from GB838311519A external-priority patent/GB8311519D0/en
Priority claimed from GB838326362A external-priority patent/GB8326362D0/en
Application filed by Fisons Ltd filed Critical Fisons Ltd
Publication of ES8701724A1 publication Critical patent/ES8701724A1/en
Publication of ES531940A0 publication Critical patent/ES531940A0/en
Expired legal-status Critical Current

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  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

Pyridine derivs. of formula (I) and their acid-addn. salts when a basic N atom is present are new. R1 = benzofurazanyl or pyridyl or Ph (the last 2 gps. being opt. substd. by halogen, NO2, CN, OR9, S(O)pR9, 1-6C alkyl or 1-6C haloalkyl); p = 0,1 or 2; R9 = 1-6C alkyl; R2, R3 = H, 1-6C alkyl, (opt. substd. by halogen, CN, XR4, NR5R6 or Ph), 3-8C cycloalkyl (opt. substd. by 1-6C alkyl), or a 4-, 5- or 6-membered O- or N-contg. hetero-cyclic ring (opt. substd. by 1-6C alkyl, itself opt. substd. by Ph gp(s)); R5, R6 = 1-6C alkyl (opt. substd. by Ph); Y+Z = bond; or Y = H; and Z = OH when R8 = electron-withdrawing gp.; one of R7, R8 = 1-6C alkyl; and the other = CONR10R11, CSNH2, C(=NH)SR9, S(O)mR9, Ph (opt. substd. by 1-6C alkyl, 1-6C alkoxy, halogen or NO2), 1-6C haloalkyl or furanyl; or R7,R8= Ph (opt. substd. by 1-6C alkyl, halogen, 1-6C alkoxy, or NO2), NH2, 1-6C haloalkyl, CN, CH2OH, CHO or CH(OR9)2; X = O or S; R4 = 1-6C alkyl or Ph; R10,R11 = H or 1-6C alkyl; or NR10R11 = 5- or 6-membered heterocyclic ring.
ES531940A 1983-04-27 1984-04-26 New tetra:hydro-3,5-pyridine-di:carboxylic acid derivs. Expired ES8701724A1 (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
GB838311520A GB8311520D0 (en) 1983-04-27 1983-04-27 Nitrogen heterocycles
GB838311521A GB8311521D0 (en) 1983-04-27 1983-04-27 Nitrogen heterocycles
GB838311519A GB8311519D0 (en) 1983-04-27 1983-04-27 Nitrogen heterocycles
GB838326362A GB8326362D0 (en) 1983-10-01 1983-10-01 Nitrogen heterocyclic compounds

Publications (2)

Publication Number Publication Date
ES8701724A1 true ES8701724A1 (en) 1986-12-01
ES531940A0 ES531940A0 (en) 1986-12-01

Family

ID=27449467

Family Applications (1)

Application Number Title Priority Date Filing Date
ES531940A Expired ES8701724A1 (en) 1983-04-27 1984-04-26 New tetra:hydro-3,5-pyridine-di:carboxylic acid derivs.

Country Status (1)

Country Link
ES (1) ES8701724A1 (en)

Also Published As

Publication number Publication date
ES531940A0 (en) 1986-12-01

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