ES8607929A1 - Un procedimiento para preparar un 10-ftalil-1, 5-diprotegido-1, 5, 10-triazadecano - Google Patents

Un procedimiento para preparar un 10-ftalil-1, 5-diprotegido-1, 5, 10-triazadecano

Info

Publication number
ES8607929A1
ES8607929A1 ES535991A ES535991A ES8607929A1 ES 8607929 A1 ES8607929 A1 ES 8607929A1 ES 535991 A ES535991 A ES 535991A ES 535991 A ES535991 A ES 535991A ES 8607929 A1 ES8607929 A1 ES 8607929A1
Authority
ES
Spain
Prior art keywords
preparation
diprotected
intermediates
triazadecane
triazadecanes
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES535991A
Other languages
English (en)
Other versions
ES535991A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Microbial Chemistry Research Foundation
Original Assignee
Microbial Chemistry Research Foundation
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Microbial Chemistry Research Foundation filed Critical Microbial Chemistry Research Foundation
Publication of ES535991A0 publication Critical patent/ES535991A0/es
Publication of ES8607929A1 publication Critical patent/ES8607929A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/44—Iso-indoles; Hydrogenated iso-indoles
    • C07D209/48—Iso-indoles; Hydrogenated iso-indoles with oxygen atoms in positions 1 and 3, e.g. phthalimide
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Indole Compounds (AREA)
  • Steroid Compounds (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Lubricants (AREA)
  • Cosmetics (AREA)
  • Blow-Moulding Or Thermoforming Of Plastics Or The Like (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)

Abstract

PROCEDIMIENTO DE SINTESIS DE 10-FTALIL-1,5-DIPROTEGIDO-1,5,10-TRIAZADECANO. COMPRENDE: A) HACER REACCIONAR UN C.D.F. (II) CON UN HALURO DE BENCILOXICARBONILO, EN PRESENCIA DE UN ETER CORONA Y TRIETILAMINA, A TEMPERATURA AMBIENTE, PARA OBTENER UN C.D.F. (III); B) SEPARAR AL ETER CORONA; Y C) HACER REACCIONAR EL C.D.F. (III) CON UN DERIVADO DE TERC-ALCOXICARBONILO EN UN DISOLVENTE COMO TRIETILAMINA, A TEMPERATURA AMBIENTE, PARA OBTENER UN COMPUESTO DE FORMULA (I). SIENDO: R1 Y R2 IGUALES, Y REPRESENTANDO CADA UNO UN GRUPO FALLIDO PROTECTOR DE AMINO DISTINTO DEL GRUPO FALLIDO; C.D.F., COMPUESTO DE FORMULA. SE UTILIZAN COMO MATERIAL DE PARTIDA PARA FABRICAR AGENTES ANTITUMORA
ES535991A 1983-02-24 1984-09-17 Un procedimiento para preparar un 10-ftalil-1, 5-diprotegido-1, 5, 10-triazadecano Expired ES8607929A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP58028499A JPS59155351A (ja) 1983-02-24 1983-02-24 １，５−ジ保護−１，５，１０−トリアザデカンおよびその製造法

Publications (2)

Publication Number Publication Date
ES535991A0 ES535991A0 (es) 1986-06-01
ES8607929A1 true ES8607929A1 (es) 1986-06-01

Family

ID=12250359

Family Applications (3)

Application Number Title Priority Date Filing Date
ES529945A Granted ES529945A0 (es) 1983-02-24 1984-02-22 Un procedimiento para preparar un 1, 5-triazadecano diprotegido en 1, 5
ES535991A Expired ES8607929A1 (es) 1983-02-24 1984-09-17 Un procedimiento para preparar un 10-ftalil-1, 5-diprotegido-1, 5, 10-triazadecano
ES545797A Expired ES8609203A1 (es) 1983-02-24 1985-08-01 Un procedimiento para preparar 1,5,10-triazadecanos susti- tuidos en posicion 5

Family Applications Before (1)

Application Number Title Priority Date Filing Date
ES529945A Granted ES529945A0 (es) 1983-02-24 1984-02-22 Un procedimiento para preparar un 1, 5-triazadecano diprotegido en 1, 5

Family Applications After (1)

Application Number Title Priority Date Filing Date
ES545797A Expired ES8609203A1 (es) 1983-02-24 1985-08-01 Un procedimiento para preparar 1,5,10-triazadecanos susti- tuidos en posicion 5

Country Status (9)

Country Link
EP (1) EP0117501B1 (es)
JP (1) JPS59155351A (es)
AT (1) ATE33384T1 (es)
DE (1) DE3470304D1 (es)
DK (1) DK93884A (es)
ES (3) ES529945A0 (es)
HU (1) HU193554B (es)
IE (1) IE56923B1 (es)
ZA (1) ZA841326B (es)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2724379B1 (fr) * 1994-09-13 1996-11-29 Fournier Sca Lab Procede de fabrication de polyamines qui sont des homologues structuraux de la spermidine.

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB744587A (en) * 1953-03-20 1956-02-08 Parke Davis & Co O-(n-carbobenzoxyglycyl)-n-carbobenzoxyserines
US3341568A (en) * 1963-09-05 1967-09-12 Dow Chemical Co Dicarbamates
FR2076639A5 (es) * 1970-01-21 1971-10-15 Inst Francais Du Petrole

Also Published As

Publication number Publication date
IE56923B1 (en) 1992-01-29
JPS59155351A (ja) 1984-09-04
EP0117501B1 (en) 1988-04-06
ES8506583A1 (es) 1985-07-16
ES535991A0 (es) 1986-06-01
DK93884D0 (da) 1984-02-23
ES529945A0 (es) 1985-07-16
ES8609203A1 (es) 1986-07-16
ATE33384T1 (de) 1988-04-15
HU193554B (en) 1987-10-28
DK93884A (da) 1984-08-25
EP0117501A1 (en) 1984-09-05
IE840429L (en) 1984-08-24
ZA841326B (en) 1984-10-31
DE3470304D1 (en) 1988-05-11
JPH0337546B2 (es) 1991-06-05
ES545797A0 (es) 1986-07-16

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Legal Events

Date Code Title Description
MM4A Patent lapsed

Effective date: 19960401