ES8607025A1 - Procedimiento de obtencion de un anticuerpo monoclonal reactivo con antigenos de esporozoitos de eimeria tenella - Google Patents

Procedimiento de obtencion de un anticuerpo monoclonal reactivo con antigenos de esporozoitos de eimeria tenella

Info

Publication number
ES8607025A1
ES8607025A1 ES535203A ES535203A ES8607025A1 ES 8607025 A1 ES8607025 A1 ES 8607025A1 ES 535203 A ES535203 A ES 535203A ES 535203 A ES535203 A ES 535203A ES 8607025 A1 ES8607025 A1 ES 8607025A1
Authority
ES
Spain
Prior art keywords
monoclonal antibodies
antigens
eimeria spp
antibodies reactive
reactive against
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES535203A
Other languages
English (en)
Other versions
ES535203A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Wyeth Holdings LLC
Original Assignee
American Cyanamid Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by American Cyanamid Co filed Critical American Cyanamid Co
Publication of ES535203A0 publication Critical patent/ES535203A0/es
Publication of ES8607025A1 publication Critical patent/ES8607025A1/es
Expired legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/20—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans from protozoa
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/44—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from protozoa
    • C07K14/455—Eimeria
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Zoology (AREA)
  • Virology (AREA)
  • Microbiology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Toxicology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)

Abstract

PROCEDIMIENTO PARA LA OBTENCION DE ANTICUERPOS MONOCLONALES REACTIVOS CON ANTIGENOS DE ESPOROZOITOS DE EIMERIA TENELLA. CONSISTE EN INMUNIZAR RATONES CON ESPOROZOITOS DE E. TENELLA; SEPARAR LOS BAZOS DE ESTOS RATONES Y PREPARAR UNA SUSPENSION DE LAS CELULAS DE LOS BAZOS; FUSIONAR ESTAS CELULAS CON CELULAS DE MIELOMA DE RATON EN PRESENCIA DE UN PROMOTOR DE FUSION; DILUIR Y CULTIVAR LAS CELULAS FUSIONADAS EN POZOS SEPARADOS, EN UN MEDIO QUE NO SOPORTA EL CRECIMIENTO DE CELULAS SIN FUSIONAR; VALORAR LA PARTE SOBRENADANTE DE CADA POZO QUE CONTIENE UN HIBRIDOMA RESPECTO A LA PRESENCIA DE ANTICUERPO REACTIVO CON ESPOROZOITOS DE E. TENELLA; SELECCIONAR Y CLONAR UN HIBRIDOMA PRODUCTOR DE ANTICUERPO CON ESPOROZOITOS DE E. TENELLA; Y RECUPERAR EL ANTICUERPO A PARTIR DE LA PARTE SOBRENADANTE. ESTOS ANTIGENOS TIENEN APLICACIONES FARMACOLOGICAS PARA LA PREVENCION Y EL TRATAMIENTO DE LA COCCIDIOSIS.
ES535203A 1983-08-19 1984-08-16 Procedimiento de obtencion de un anticuerpo monoclonal reactivo con antigenos de esporozoitos de eimeria tenella Expired ES8607025A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US52481983A 1983-08-19 1983-08-19

Publications (2)

Publication Number Publication Date
ES535203A0 ES535203A0 (es) 1986-06-01
ES8607025A1 true ES8607025A1 (es) 1986-06-01

Family

ID=24090798

Family Applications (4)

Application Number Title Priority Date Filing Date
ES535203A Expired ES8607025A1 (es) 1983-08-19 1984-08-16 Procedimiento de obtencion de un anticuerpo monoclonal reactivo con antigenos de esporozoitos de eimeria tenella
ES545607A Expired ES8606901A1 (es) 1983-08-19 1985-07-26 Procedimiento para preparar una vacuna contra la coccidiosis
ES551496A Expired ES8900008A1 (es) 1983-08-19 1986-01-31 Procedimiento de obtencion de un anticuerpo monoclonal reactivo con antigenos de esporozoitos de eimeria spp.
ES551497A Expired ES8802164A1 (es) 1983-08-19 1986-01-31 Procedimiento de obtencion de un anticuerpo monoclonal reactivo con antigenos de esporozoitos de eimeria spp.

Family Applications After (3)

Application Number Title Priority Date Filing Date
ES545607A Expired ES8606901A1 (es) 1983-08-19 1985-07-26 Procedimiento para preparar una vacuna contra la coccidiosis
ES551496A Expired ES8900008A1 (es) 1983-08-19 1986-01-31 Procedimiento de obtencion de un anticuerpo monoclonal reactivo con antigenos de esporozoitos de eimeria spp.
ES551497A Expired ES8802164A1 (es) 1983-08-19 1986-01-31 Procedimiento de obtencion de un anticuerpo monoclonal reactivo con antigenos de esporozoitos de eimeria spp.

Country Status (13)

Country Link
EP (1) EP0135712A3 (es)
JP (2) JPS6067499A (es)
KR (1) KR850001697A (es)
AU (1) AU585484B2 (es)
CA (1) CA1241923A (es)
DK (2) DK397184A (es)
ES (4) ES8607025A1 (es)
FI (1) FI83667C (es)
IL (1) IL72656A (es)
NO (1) NO162179C (es)
NZ (1) NZ209077A (es)
PT (1) PT79075B (es)
ZA (1) ZA846433B (es)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0135073A3 (en) * 1983-08-19 1987-05-27 American Cyanamid Company Antigens and monoclonal antibodies reactive against merozites of eimeria spp.
CA1340520C (en) * 1984-06-05 1999-05-04 Karel Z. Newman Jr. Antigenic proteins and vaccines containing them and protective antibodies directed to them for prevention of coccidiosis caused by eimeria tenella and eimeria necatrix
US4639372A (en) * 1984-06-29 1987-01-27 Merck & Co., Inc. Coccidiosis vaccine
US5273901A (en) * 1984-07-05 1993-12-28 Enzon Corp. Genetically engineered coccidiosis sporozoite 21.5 Kb antigen, ac-6b
EP0190254A4 (en) * 1984-07-05 1987-03-09 Genex Corp GENE CLONE AND PROCESS FOR THE PREPARATION AND USE THEREOF.
US5279960A (en) * 1984-07-05 1994-01-18 Enzon Corp. 25 KD coccidial antigen of eimeria tenella
US4724145A (en) * 1985-11-18 1988-02-09 Merck & Co., Inc. Eimeria acervulina immunogens
EP0231537B1 (en) 1985-12-03 1992-03-11 Solvay Antigenic proteins and vaccines containing them for prevention of coccidiosis
EP0241139A3 (en) * 1986-03-13 1989-04-19 Merck & Co. Inc. Anti-idiotypic vaccine for coccidiosis
CA1340838C (en) 1986-08-14 1999-12-07 Michael Wallach Coccidiosis vacine
US5496550A (en) * 1986-08-14 1996-03-05 Chilwalner Method of reducing the output of Eimeria oocysts from a newborn chick
EP0614973A1 (en) * 1987-03-06 1994-09-14 Amgen Boulder Inc. Polypeptide useful in diagnosis of coccidia infection and recombinant-DNA methods for manufacturing same
ZA893740B (en) * 1988-06-03 1990-02-28 Hoffmann La Roche Recombinant coccidiosis vaccines
ZA902147B (en) * 1989-03-28 1990-12-28 Akzo Nv Coccidiosis vaccine
JPH06504187A (ja) * 1990-09-12 1994-05-19 ジェネックス・コーポレーション 遺伝子操作されたコクシジウム症ワクチン
US5403581A (en) * 1991-07-12 1995-04-04 Hoffmann-La Roche Inc. Coccidiosis vaccines
US6008342A (en) * 1991-07-12 1999-12-28 Roche Vitamins Inc. DNA encoding eimeria antigen
EP0872486A1 (en) * 1997-04-09 1998-10-21 Akzo Nobel N.V. Eimeria proteins as vaccines
US6680061B1 (en) 1998-10-07 2004-01-20 Theodorus Cornelis Schaap Coccidiosis vaccines
EP1478654B1 (en) 2001-07-06 2010-01-06 ABIC Biological Laboratories Ltd. NUCLEIC ACIDS ENCODING A RECOMBINANT 250 kDa ANTIGEN FROM SPOROZOITES/MEROZOITES OF EIMERIA MAXIMA AND THEIR USES
ZA200400479B (en) 2001-07-06 2006-05-31 Abic Biolog Lab Teva Nucleic acids encoding recombinant 56 a 82 KDA antigens from gametocytes of Eimeria maxima and their use
JP2003088370A (ja) * 2001-09-03 2003-03-25 Avicore Biotechnology Institute Inc 鳥類コクシジウム症を誘発するアイメリア種のスポロゾイトの表面抗原に対するｓｃＦｖ組換え抗体
JP6155758B2 (ja) * 2013-03-29 2017-07-05 株式会社Ihi 低温液体タンク
CN106046136B (zh) * 2016-06-03 2019-02-22 山东农业大学 一种鸡柔嫩艾美尔球虫微线蛋-2突变体EtMIC2-2119

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5649323A (en) * 1979-09-29 1981-05-02 Nisshin Flour Milling Co Ltd Coccidiostat
EP0135073A3 (en) * 1983-08-19 1987-05-27 American Cyanamid Company Antigens and monoclonal antibodies reactive against merozites of eimeria spp.
US4639372A (en) * 1984-06-29 1987-01-27 Merck & Co., Inc. Coccidiosis vaccine

Also Published As

Publication number Publication date
IL72656A (en) 1989-06-30
FI843142A0 (fi) 1984-08-09
NO162179C (no) 1989-11-22
JPS6067499A (ja) 1985-04-17
AU585484B2 (en) 1989-06-22
ES535203A0 (es) 1986-06-01
ES8900008A1 (es) 1988-11-16
DK304590D0 (da) 1990-12-21
FI83667C (fi) 1991-08-12
NO162179B (no) 1989-08-14
ES8606901A1 (es) 1986-05-16
DK162171C (da) 1992-03-16
NO843293L (no) 1985-02-20
EP0135712A2 (en) 1985-04-03
PT79075B (en) 1986-07-22
CA1241923A (en) 1988-09-13
NZ209077A (en) 1988-08-30
ES8802164A1 (es) 1988-04-01
PT79075A (en) 1984-09-01
ZA846433B (en) 1985-03-27
EP0135712A3 (en) 1987-05-27
KR850001697A (ko) 1985-04-01
FI843142A (fi) 1985-02-20
DK397184D0 (da) 1984-08-17
AU3133284A (en) 1985-02-21
DK304590A (da) 1990-12-21
CA1261285C (es) 1989-09-26
DK162171B (da) 1991-09-23
IL72656A0 (en) 1984-11-30
DK397184A (da) 1985-02-20
JPH05317080A (ja) 1993-12-03
ES551496A0 (es) 1988-11-16
ES545607A0 (es) 1986-05-16
ES551497A0 (es) 1988-04-01
FI83667B (fi) 1991-04-30

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Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 19970519