ES8606659A1 - Un metodo para detectar anticuerpos en suero o fluido - Google Patents
Un metodo para detectar anticuerpos en suero o fluidoInfo
- Publication number
- ES8606659A1 ES8606659A1 ES536211A ES536211A ES8606659A1 ES 8606659 A1 ES8606659 A1 ES 8606659A1 ES 536211 A ES536211 A ES 536211A ES 536211 A ES536211 A ES 536211A ES 8606659 A1 ES8606659 A1 ES 8606659A1
- Authority
- ES
- Spain
- Prior art keywords
- detected
- stabilization
- destabilization
- response
- compositions
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
- G01N33/554—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being a biological cell or cell fragment, e.g. bacteria, yeast cells
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/564—Immunoassay; Biospecific binding assay; Materials therefor for pre-existing immune complex or autoimmune disease, i.e. systemic lupus erythematosus, rheumatoid arthritis, multiple sclerosis, rheumatoid factors or complement components C1-C9
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/10—Musculoskeletal or connective tissue disorders
- G01N2800/101—Diffuse connective tissue disease, e.g. Sjögren, Wegener's granulomatosis
- G01N2800/104—Lupus erythematosus [SLE]
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S436/00—Chemistry: analytical and immunological testing
- Y10S436/829—Liposomes, e.g. encapsulation
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T428/00—Stock material or miscellaneous articles
- Y10T428/29—Coated or structually defined flake, particle, cell, strand, strand portion, rod, filament, macroscopic fiber or mass thereof
- Y10T428/2982—Particulate matter [e.g., sphere, flake, etc.]
- Y10T428/2984—Microcapsule with fluid core [includes liposome]
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Immunology (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Hematology (AREA)
- Molecular Biology (AREA)
- Chemical & Material Sciences (AREA)
- Urology & Nephrology (AREA)
- Cell Biology (AREA)
- Microbiology (AREA)
- Analytical Chemistry (AREA)
- Biotechnology (AREA)
- Food Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- Physics & Mathematics (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Mycology (AREA)
- Rehabilitation Therapy (AREA)
- Rheumatology (AREA)
- Medicinal Preparation (AREA)
Abstract
UN METODO PARA DETECTAR ANTICUERPOS EN SUERO O FLUIDO. LA PRESENCIA DE ANTICUERPOS AFINES EN MUESTRA DE ENSAYO SE DETECTA POR ALTERACION DE LA ESTRUCTURA SUPRAMOLECULAR DE LOS LIPOSOMAS, QUE TIENE COMO RESULTADO UNOS CAMBIOS DE ESTABILIZACION. LA DESESTABILIZACION SE PUEDE DETECTAR, Y EN CIERTOS CASOS PUEDE SER CAUSADA, POR ADICION DE IONES MAGNESIO O CALCIO. LA ESTABILIZACION AUMENTADA SE PUEDE DETECTAR POR LA POLIMERIZACION DE LOS COMPONENTES DE LA BICAPA COMO RESPUESTA A LUZ ULTRAVIOLETA. LAS INTERACCIONES ANTICUERPO-ANTIGENO EN LA SUPERFICIE DEL LIPOSOMA MEDIATIZAN LA RESPUESTA DE ESTABILIZACION/DESESTABILIZACION.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US06/535,884 US4668638A (en) | 1983-03-24 | 1983-09-26 | Liposome composition for lupus assay |
Publications (2)
Publication Number | Publication Date |
---|---|
ES536211A0 ES536211A0 (es) | 1986-04-01 |
ES8606659A1 true ES8606659A1 (es) | 1986-04-01 |
Family
ID=24136197
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES536211A Expired ES8606659A1 (es) | 1983-09-26 | 1984-09-25 | Un metodo para detectar anticuerpos en suero o fluido |
Country Status (9)
Country | Link |
---|---|
US (1) | US4668638A (es) |
EP (1) | EP0138685A3 (es) |
JP (1) | JPS61500182A (es) |
AU (1) | AU3436684A (es) |
DK (1) | DK234785D0 (es) |
ES (1) | ES8606659A1 (es) |
GR (1) | GR80483B (es) |
WO (1) | WO1985001580A1 (es) |
ZA (1) | ZA847573B (es) |
Families Citing this family (20)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5622871A (en) | 1987-04-27 | 1997-04-22 | Unilever Patent Holdings B.V. | Capillary immunoassay and device therefor comprising mobilizable particulate labelled reagents |
US4957735A (en) * | 1984-06-12 | 1990-09-18 | The University Of Tennessee Research Corporation | Target-sensitive immunoliposomes- preparation and characterization |
US4801459A (en) * | 1986-08-05 | 1989-01-31 | Liburdy Robert P | Technique for drug and chemical delivery |
US5190761A (en) * | 1986-08-05 | 1993-03-02 | Liburdy Robert P | Electromagnetic field triggered drug and chemical delivery via liposomes |
US4962022A (en) * | 1986-09-22 | 1990-10-09 | Becton Dickinson And Company | Storage and use of liposomes |
EP1248112A3 (en) | 1987-04-27 | 2004-08-25 | Inverness Medical Switzerland GmbH | Immunochromatographic specific binding assay device |
JPH0194261A (ja) * | 1987-07-13 | 1989-04-12 | Univ Tennessee Res Corp | 酵素関与するアッセイのために、均一系でリポソームを利用してシグナルを増幅する方法 |
US5258503A (en) * | 1987-09-08 | 1993-11-02 | Kanegafuchi Kagaku Kogyo Kabushiki Kaisha | Autoantibody adsorbent and apparatus for removing autoantibodies using the same |
US4913902A (en) * | 1987-11-10 | 1990-04-03 | North Carolina State University | Purification by affinity binding to liposomes |
US5167925A (en) * | 1988-06-08 | 1992-12-01 | North Carolina State University | Precipitation of multivalent antiligands with affinity surfactants |
US5112770A (en) * | 1988-06-08 | 1992-05-12 | North Carolina State University | Precipitation of multivalent antiligands with affinity surfactants |
US6352862B1 (en) * | 1989-02-17 | 2002-03-05 | Unilever Patent Holdings B.V. | Analytical test device for imuno assays and methods of using same |
WO1990015594A1 (en) * | 1989-06-16 | 1990-12-27 | Liburdy, Robert, P. | Electromagnetic field triggered drug and chemical delivery via liposomes |
ATE142789T1 (de) * | 1989-10-19 | 1996-09-15 | Yamasa Shoyu Kk | Träger zur bindung von antiphospholipid- antikörpern, diese antikörper verwendender immunotest und kit dafür |
FR2657885A1 (fr) * | 1990-02-08 | 1991-08-09 | Cird | Anticorps capables de reconnaitre specifiquement un antigene du stratum corneum de l'epiderme humain, leur preparation et leur application, notamme comme vecteurs de drogues. |
US5556637A (en) * | 1990-08-06 | 1996-09-17 | A. Nattermann & Cie. Gmbh | Water containing liposome system |
EP0772778B1 (en) | 1994-07-23 | 1999-10-27 | Roche Diagnostics GmbH | Method for the determination of the prethrombotic state |
US5776487A (en) * | 1996-04-19 | 1998-07-07 | Pasteur Sanofi Diagnostics | Liposome reagents for immunoassays |
US5780319A (en) * | 1996-04-19 | 1998-07-14 | Pasteur Sanofi Diagnostics | Immunoassays to detect antiphospholipid antibodies |
WO1998004743A1 (en) * | 1996-07-29 | 1998-02-05 | The Regents Of The University Of California | Polymeric assemblies for sensitive colorimetric assays |
Family Cites Families (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4235792A (en) * | 1977-04-14 | 1980-11-25 | The Governing Council Of The University Of Toronto | Immunological materials |
US4193983A (en) * | 1978-05-16 | 1980-03-18 | Syva Company | Labeled liposome particle compositions and immunoassays therewith |
US4234563A (en) * | 1978-06-02 | 1980-11-18 | American Hospital Supply Corporation | Insolubilized deoxyribonucleic acid (DNA) |
US4255411A (en) * | 1978-11-27 | 1981-03-10 | Damon Corporation | Process of determining an immunogenic substance by competition with an antibody in a microcapsule |
GB2026340B (en) * | 1978-07-03 | 1982-12-22 | Ash P | Stabilising microvesicles |
DE3000483A1 (de) * | 1979-01-09 | 1980-07-17 | Fuji Photo Film Co Ltd | Mikrokapseln fuer immunologische bestimmungen |
US4372745A (en) * | 1979-12-19 | 1983-02-08 | Electro-Nucleonics, Inc. | Chemical luminescence amplification substrate system for immunochemistry involving microencapsulated fluorescer |
US4342826A (en) * | 1980-02-04 | 1982-08-03 | Collaborative Research, Inc. | Immunoassay products and methods |
US4329331A (en) * | 1980-03-13 | 1982-05-11 | Kallick Charles A | Diagnostic method for detection of systemic lupus erythematosus |
US4483921A (en) * | 1981-01-12 | 1984-11-20 | Collaborative Research, Inc. | Immunoassay with antigen or antibody labeled liposomes sequestering enzyme |
JPS5842971A (ja) * | 1981-09-07 | 1983-03-12 | Fuji Photo Film Co Ltd | 抗体を感作させたマイクロカプセルを用いる細胞性免疫測定法 |
US4483929A (en) * | 1982-05-03 | 1984-11-20 | Liposome Technology Incorporated | Liposomes with glycolipid-linked antibodies |
-
1983
- 1983-09-26 US US06/535,884 patent/US4668638A/en not_active Expired - Lifetime
-
1984
- 1984-09-25 ES ES536211A patent/ES8606659A1/es not_active Expired
- 1984-09-26 EP EP84401925A patent/EP0138685A3/en not_active Withdrawn
- 1984-09-26 GR GR80483A patent/GR80483B/el unknown
- 1984-09-26 ZA ZA847573A patent/ZA847573B/xx unknown
- 1984-09-26 JP JP59503689A patent/JPS61500182A/ja active Pending
- 1984-09-26 WO PCT/US1984/001541 patent/WO1985001580A1/en unknown
- 1984-09-26 AU AU34366/84A patent/AU3436684A/en not_active Abandoned
-
1985
- 1985-05-24 DK DK234785A patent/DK234785D0/da not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
US4668638A (en) | 1987-05-26 |
DK234785A (da) | 1985-05-24 |
ZA847573B (en) | 1985-05-29 |
JPS61500182A (ja) | 1986-01-30 |
WO1985001580A1 (en) | 1985-04-11 |
GR80483B (en) | 1985-01-28 |
AU3436684A (en) | 1985-04-23 |
ES536211A0 (es) | 1986-04-01 |
EP0138685A2 (en) | 1985-04-24 |
DK234785D0 (da) | 1985-05-24 |
EP0138685A3 (en) | 1988-04-27 |
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