ES8605804A1 - Procedimiento de obtencion de carboxamidas de 1,2 benzotia- zina - Google Patents
Procedimiento de obtencion de carboxamidas de 1,2 benzotia- zinaInfo
- Publication number
- ES8605804A1 ES8605804A1 ES549754A ES549754A ES8605804A1 ES 8605804 A1 ES8605804 A1 ES 8605804A1 ES 549754 A ES549754 A ES 549754A ES 549754 A ES549754 A ES 549754A ES 8605804 A1 ES8605804 A1 ES 8605804A1
- Authority
- ES
- Spain
- Prior art keywords
- methyl
- deriv
- prodn
- saccharin
- give
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Landscapes
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Abstract
PROCEDIMIENTO DE OBTENCION DE CARBOXIAMIDAS DE 1,2-BENZOTIAZINA. COMPRENDE: A) METILAR A LA SACARINA CON IODURO DE METILO EN DIMETILFORMAMIDA; B) DILUIR A LA MEZCLA DE REACCION DE A) CON AGUA, PARA DAR LA N-METILSACARINA D.F. (II); C) HACER REACCIONAR A (II) CON CLOROACETONITRILO, EN DIMETILFORMAMIDA SECA, PARA CONSEGUIR A (A) D.F. (III); D) TRATAR A (III) A REFLUJO CON UNA SOLUCION DE H2O2 Y NAOH, PARA PRODUCIR (B) D.F. (IV); E) TRANSAMIDAR A (IV) CON 2-AMINOPIRIDINA O CON 3-AMINO-5-METILIXAZOL, EN XILENO; Y F) PRECIPITAR A LA MEZCLA DE E) EN UNA SOLUCION DILUIDA DE MINERAL, PARA OBTENER A (C) D.F. (I). SIENDO: D.F., DE FORMUA; (A), 3-CIANO-A-B-C; (B), 3-CARBAMOIL-A-B-C; (C), A-N-(2-PIRIDIL)-B-3-CARBOXAMIDA-C; A, 4-HIDROXI-2-; (B), 2H-1,2-BENZOTIAZINA; (C), 1,1-DIOXIDO; Y R, 2-PIRIDIL O 5-METILISOXAZOLIL. SE UTILIZAN COMO ANTIINFLAMATORIOS Y ANTIRREUMATICOS.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ES549754A ES8605804A1 (es) | 1985-12-10 | 1985-12-10 | Procedimiento de obtencion de carboxamidas de 1,2 benzotia- zina |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ES549754A ES8605804A1 (es) | 1985-12-10 | 1985-12-10 | Procedimiento de obtencion de carboxamidas de 1,2 benzotia- zina |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| ES8605804A1 true ES8605804A1 (es) | 1986-04-01 |
| ES549754A0 ES549754A0 (es) | 1986-04-01 |
Family
ID=8490397
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES549754A Expired ES8605804A1 (es) | 1985-12-10 | 1985-12-10 | Procedimiento de obtencion de carboxamidas de 1,2 benzotia- zina |
Country Status (1)
| Country | Link |
|---|---|
| ES (1) | ES8605804A1 (es) |
-
1985
- 1985-12-10 ES ES549754A patent/ES8605804A1/es not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| ES549754A0 (es) | 1986-04-01 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FD1A | Patent lapsed |
Effective date: 19970401 |