ES8604608A1 - Un procedimiento para preparar una sustancia antibiotica seleccionada del antibiotico l 17054 y sus sales por adicion de acidos farmaceuticamente acepatables - Google Patents

Un procedimiento para preparar una sustancia antibiotica seleccionada del antibiotico l 17054 y sus sales por adicion de acidos farmaceuticamente acepatables

Info

Publication number
ES8604608A1
ES8604608A1 ES538606A ES538606A ES8604608A1 ES 8604608 A1 ES8604608 A1 ES 8604608A1 ES 538606 A ES538606 A ES 538606A ES 538606 A ES538606 A ES 538606A ES 8604608 A1 ES8604608 A1 ES 8604608A1
Authority
ES
Spain
Prior art keywords
teicoplanin
chemical process
cpd
preparing antibiotic
residue
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES538606A
Other languages
English (en)
Other versions
ES538606A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Gruppo Lepetit SpA
Original Assignee
Gruppo Lepetit SpA
Lepetit SpA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Gruppo Lepetit SpA, Lepetit SpA filed Critical Gruppo Lepetit SpA
Publication of ES8604608A1 publication Critical patent/ES8604608A1/es
Publication of ES538606A0 publication Critical patent/ES538606A0/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K9/00—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof
    • C07K9/006—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof the peptide sequence being part of a ring structure
    • C07K9/008—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof the peptide sequence being part of a ring structure directly attached to a hetero atom of the saccharide radical, e.g. actaplanin, avoparcin, ristomycin, vancomycin
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S930/00—Peptide or protein sequence
    • Y10S930/01—Peptide or protein sequence
    • Y10S930/19—Antibiotic
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S930/00—Peptide or protein sequence
    • Y10S930/01—Peptide or protein sequence
    • Y10S930/27—Cyclic peptide or cyclic protein

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Compounds Of Unknown Constitution (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)

Abstract

UN PROCEDIMIENTO PARA PREPARAR UNA SUSTANCIA ANTIBIOTICA SELECCIONADA DEL ANTIBIOTICO L 17054 Y SUS SALES DE ADICION FARMACEUTICAMENTE ACEPTABLES. CONSISTENTE EN SOMETER UNA PREPARACION EN BRUTO O PURA DEL ANTIBIOTICO TEICOPLANINA, UNO DE SUS FACTORES O DE SUS COMPONENTES O UNA MEZCLA DE LOS FACTORES O COMPONENTES EN CUALQUIER PROPORCION A UNA REACCION DE HIDROLISIS ACIDA EN UN ACIDO ACUOSO CONCENTRADO Y FUERTE COMO EL ACIDO TRIFLUOROACETICO ACUOSO A UNA CONCENTRACION ENTRE 75% Y 95% Y A UNA TEMPERATURA ENTRE 10 Y 50JC, SEGUIDO SI ES NECESARIO DE PURIFICACION, PARA OBTENER COMPUESTOS DE FORMULA (I). SIENDO: A, H; B ES N-ACETIL-B-D-GLUCOSAMINILO Y Z ES A-D-MANOSILO. SE UTILIZA POR SU ACTIVIDAD ANTIMICROBIANA PRINCIPALMENTE FRENTE A LAS BACTERIAS GRAM-POSITIVAS.
ES538606A 1983-12-16 1984-12-14 Un procedimiento para preparar una sustancia antibiotica seleccionada del antibiotico l 17054 y sus sales por adicion de acidos farmaceuticamente acepatables Expired ES8604608A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB838333624A GB8333624D0 (en) 1983-12-16 1983-12-16 Antibiotics l 17054 and l 17392

Publications (2)

Publication Number Publication Date
ES8604608A1 true ES8604608A1 (es) 1986-02-01
ES538606A0 ES538606A0 (es) 1986-02-01

Family

ID=10553427

Family Applications (1)

Application Number Title Priority Date Filing Date
ES538606A Expired ES8604608A1 (es) 1983-12-16 1984-12-14 Un procedimiento para preparar una sustancia antibiotica seleccionada del antibiotico l 17054 y sus sales por adicion de acidos farmaceuticamente acepatables

Country Status (22)

Country Link
US (1) US4594187A (es)
EP (1) EP0146822B1 (es)
JP (1) JPS60146895A (es)
KR (1) KR850004497A (es)
AR (1) AR241597A1 (es)
AT (1) ATE51875T1 (es)
AU (1) AU574408B2 (es)
CA (1) CA1250094A (es)
DE (1) DE3481914D1 (es)
DK (1) DK584484A (es)
ES (1) ES8604608A1 (es)
FI (1) FI86433C (es)
GB (1) GB8333624D0 (es)
GR (1) GR81132B (es)
HU (1) HU194283B (es)
IE (1) IE58043B1 (es)
IL (1) IL73806A (es)
NO (1) NO159094C (es)
NZ (1) NZ210545A (es)
PH (1) PH21126A (es)
PT (1) PT79682B (es)
ZA (2) ZA849392B (es)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8307847D0 (en) * 1983-03-22 1983-04-27 Lepetit Spa Antibiotics l 17054 and l 17046
IT1173329B (it) * 1984-02-21 1987-06-24 Lepetit Spa Procedimento per la trasformazione quantitativa di teicoplanina a2 fattore 1 in teicoplanina a2 fattore 3
GB8420405D0 (en) * 1984-08-10 1984-09-12 Lepetit Spa Preparing antibiotic l 17046
US5185320A (en) * 1989-04-03 1993-02-09 Gruppo Lepetit S.P.A. O56 -alkyl derivatives of aglycone and pseudo aglycones of teicoplanin
ATE117724T1 (de) * 1989-07-04 1995-02-15 Lepetit Spa Antibiotikum ge 22270, faktoren a1,a2,a3 und h.
HUT63860A (en) * 1990-12-05 1993-10-28 Lepetit Spa Process for producing 39-decarboxy-38-(hydroxymethyl) derivatives of teikoplanin antibiotics
CA2250578C (en) 1996-04-23 2003-06-24 Versicor Inc. Improved chemical process for preparing amide derivatives of antibiotic a 40926
KR100476818B1 (ko) * 2002-07-19 2005-03-17 종근당바이오 주식회사 테이코플라닌 에이 투 정제 방법

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1587685A (en) * 1977-03-09 1981-04-08 Microbial Chem Res Found Macrolactone derivatives and their production
US4486584A (en) * 1980-07-15 1984-12-04 Eli Lilly And Company Demethylmacrocin compounds and derivatives thereof
CH658250A5 (it) * 1981-01-09 1986-10-31 Pierrel Spa Nuovi antibiotici macrolidici semisintetici, procedimenti microbiologici per la loro preparazione nuovi intermedi per la loro preparazione e composizioni farmaceutiche che li contengono.
US4401660A (en) * 1981-12-14 1983-08-30 Eli Lilly And Company Ester derivatives of 5-O-mycaminosyl tylonolide and method of using same
FI75190C (fi) * 1982-03-24 1988-05-09 Lilly Co Eli Foerfarande foer framstaellning av ett antibiotikum a41030-komplex eller dess faktorer a, b, c, d, e, f och g.
FI73697C (fi) * 1982-06-08 1987-11-09 Lepetit Spa Foerfarande foer framstaellning av individuella faktorer 1, 2, 3, 4 och 5 av teikomysin a2.
GB8307847D0 (en) * 1983-03-22 1983-04-27 Lepetit Spa Antibiotics l 17054 and l 17046
US4521335A (en) * 1983-07-13 1985-06-04 Smithkline Beckman Corporation Aglycone and pseudo-aglycones of the AAD 216 antibiotics
IT1173329B (it) * 1984-02-21 1987-06-24 Lepetit Spa Procedimento per la trasformazione quantitativa di teicoplanina a2 fattore 1 in teicoplanina a2 fattore 3

Also Published As

Publication number Publication date
IL73806A0 (en) 1985-03-31
ZA849580B (en) 1985-09-25
AU574408B2 (en) 1988-07-07
IL73806A (en) 1988-05-31
PT79682A (en) 1985-01-01
GB8333624D0 (en) 1984-01-25
HU194283B (en) 1988-01-28
FI844962A0 (fi) 1984-12-14
FI844962L (fi) 1985-06-17
DE3481914D1 (de) 1990-05-17
FI86433C (fi) 1992-08-25
PH21126A (en) 1987-07-27
AR241597A1 (es) 1992-09-30
JPS60146895A (ja) 1985-08-02
GR81132B (en) 1985-03-12
NZ210545A (en) 1988-05-30
IE58043B1 (en) 1993-06-16
NO159094C (no) 1988-11-30
ATE51875T1 (de) 1990-04-15
NO159094B (no) 1988-08-22
FI86433B (fi) 1992-05-15
ZA849392B (en) 1985-09-25
ES538606A0 (es) 1986-02-01
DK584484A (da) 1985-06-17
IE843217L (en) 1985-06-16
AU3601584A (en) 1985-06-20
CA1250094A (en) 1989-02-14
US4594187A (en) 1986-06-10
HUT36839A (en) 1985-10-28
KR850004497A (ko) 1985-07-15
NO845006L (no) 1985-06-17
EP0146822A2 (en) 1985-07-03
EP0146822B1 (en) 1990-04-11
PT79682B (en) 1986-12-10
EP0146822A3 (en) 1985-08-07
DK584484D0 (da) 1984-12-07

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Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 19970401