ES8604262A1 - Procedimiento de preparacion de aspartil-fenilalanina-metil-ester - Google Patents
Procedimiento de preparacion de aspartil-fenilalanina-metil-esterInfo
- Publication number
- ES8604262A1 ES8604262A1 ES529469A ES529469A ES8604262A1 ES 8604262 A1 ES8604262 A1 ES 8604262A1 ES 529469 A ES529469 A ES 529469A ES 529469 A ES529469 A ES 529469A ES 8604262 A1 ES8604262 A1 ES 8604262A1
- Authority
- ES
- Spain
- Prior art keywords
- alkyl ester
- prepn
- aspartyl
- phenylalanine
- alpha
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Landscapes
- Peptides Or Proteins (AREA)
Abstract
PROCEDIMIENTO DE PREPARACION DE ASPARTIL-FENILALANINA-METIL-ESTER. COMPRENDE: A) TRATAR A UN COMPUESTO DE FORMULA (I) CON HIDROCLORURO DE N,N-DIMETILFORMAMIDA O DE N,N-DIMETILACETAMIDA, ENTRE C40J Y B20JC, PARA OBTENER UN COMPUESTO DE FORMULA (II); B) TRATAR A (II) CON UN CLORURO DE ACIDO DE FORMULA (R-CO-CL), ENTRE C60J Y B5JC, PARA CONSEGUIR UN COMPUESTO DE FORMULA (III); C) HACER REACCIONAR A (III) CON FENIL-ALANINA-METIL-ESTER, ENTRE C60JC Y B5JC, PARA DAR UN COMPUESTO DE FORMULA (IV); D) HIDROLIZAR A (IV) CON CLORHIDRICO, HASTA UN PH ENTRE 0 Y 1, PARA REALIZAR A (A); Y E) TRATAR A (A) CON HIDROXIDO SODICO O HIDROXIDO POTASICO HASTA UN PH ENTRE 4,5 Y 5, PARA OBTENER EL ASPARTIL-FENILALAMINA-METIL-ESTER. SIENDO: X E Y, LI, NA O K; Z, O O S; R, ALQUILICO DE C 8 A 30; Y R PIVALOIL ACETIL Y OTROS. SE UTILIZAN COMO EDULCORANTES ACALORICOS.
Priority Applications (12)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
ES529469A ES8604262A1 (es) | 1984-02-06 | 1984-02-06 | Procedimiento de preparacion de aspartil-fenilalanina-metil-ester |
EP84107902A EP0143881A3 (de) | 1983-09-07 | 1984-07-06 | Verfahren zur Herstellung eines alpha-L-Aspartyl-L-Phenylalanin-alkylesters |
FI842743A FI842743A (fi) | 1983-09-07 | 1984-07-09 | Foerfarande foer framstaellning av -l-aspartyl-l-fenylalaninalkylester. |
DK338584A DK338584A (da) | 1983-09-07 | 1984-07-10 | Fremgangsmaade til fremstilling af alfa-l-aspartyl-l-phenylalaninalkylestere |
NO842802A NO842802L (no) | 1983-09-07 | 1984-07-10 | Fremgangsmaate for fremstilling av alfa-l-aspartyl-l-fenyl-alanin-alkylestere |
DD84265160A DD219025A7 (de) | 1983-09-07 | 1984-07-11 | Verfahren zur herstellung von alpha-l-aspartyl-l-phenylalanin-alkylester |
HU842725A HUT34999A (en) | 1983-09-07 | 1984-07-12 | Process for preparing alkyl esters of alpha-l-aspartyl l-phenyl-alanina |
CS845460A CZ546084A3 (en) | 1983-09-07 | 1984-07-13 | Process for preparing l-aspartyl-l-phenylalanine-c(1-4)-alkyl esters |
RO84115323A RO90400A (ro) | 1983-09-07 | 1984-07-23 | Procedeu pentru prepararea esterilor alchilici inferiori ai & aspartil-l-fenilalaninei |
PT79022A PT79022B (pt) | 1983-09-07 | 1984-08-02 | Verfahren zur herstellung von alpha-l-aspartyl-l-phenylalaninalkylester |
BR8404378A BR8404378A (pt) | 1983-09-07 | 1984-08-31 | Processo de preparacao de ester alquilico de a-l-aspartil-l-fenila lanina e processo de preparacao de compostos |
IL72841A IL72841A0 (en) | 1983-09-07 | 1984-09-02 | Process for the preparation of a dipeptide alkyl ester and a novel intermediate used in said process |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
ES529469A ES8604262A1 (es) | 1984-02-06 | 1984-02-06 | Procedimiento de preparacion de aspartil-fenilalanina-metil-ester |
Publications (2)
Publication Number | Publication Date |
---|---|
ES529469A0 ES529469A0 (es) | 1986-02-01 |
ES8604262A1 true ES8604262A1 (es) | 1986-02-01 |
Family
ID=8486827
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES529469A Expired ES8604262A1 (es) | 1983-09-07 | 1984-02-06 | Procedimiento de preparacion de aspartil-fenilalanina-metil-ester |
Country Status (1)
Country | Link |
---|---|
ES (1) | ES8604262A1 (es) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ES2042417A1 (es) * | 1992-05-18 | 1993-12-01 | Genesis Para La Investigacion | Procedimiento de obtencion de alfa-aspartame. |
-
1984
- 1984-02-06 ES ES529469A patent/ES8604262A1/es not_active Expired
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ES2042417A1 (es) * | 1992-05-18 | 1993-12-01 | Genesis Para La Investigacion | Procedimiento de obtencion de alfa-aspartame. |
Also Published As
Publication number | Publication date |
---|---|
ES529469A0 (es) | 1986-02-01 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FD1A | Patent lapsed |
Effective date: 19960603 |