ES8603426A1 - Pyrazolopyridine derivatives - Google Patents
Pyrazolopyridine derivativesInfo
- Publication number
- ES8603426A1 ES8603426A1 ES542457A ES542457A ES8603426A1 ES 8603426 A1 ES8603426 A1 ES 8603426A1 ES 542457 A ES542457 A ES 542457A ES 542457 A ES542457 A ES 542457A ES 8603426 A1 ES8603426 A1 ES 8603426A1
- Authority
- ES
- Spain
- Prior art keywords
- group
- alkylcarbamoyl
- carboxy
- dialkylcarbamoyl
- methyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pain & Pain Management (AREA)
- Pharmacology & Pharmacy (AREA)
- Rheumatology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Pyrazolopyridine derivatives of the formula: < IMAGE > wherein R<1> represents a carboxy, alkoxycarbonyl, carbamoyl, alkylcarbamoyl or dialkylcarbamoyl group, R<2> represents a halogen atom or an alkyl, cyano, alkoxycarbonyl, carboxy, carbamoyl, alkylcarbamoyl, dialkylcarbamoyl, nitro, hydroxy, alkoxy, aryloxy, aralkyl, trifluoromethyl, alkylthio, alkylsulphinyl, alkylsulphonyl, arylthio, arylsulphinyl, arylsulphonyl, alkanoyl, aroyl or aryl group, or an amino group which may be substituted by one or two groups selected from alkyl and aryl groups, and n represents 0, 1, 2, 3 or 4, and salts thereof, with the provisos that:- (i) R<1> is alkylcarbamoyl when n is 0, (ii) R<1> is other than a dialkylcarbamoyl group when n is 1 and R<2> is a methyl group, (iii) R<1> is other than a carboxy or ethoxycarbonyl group when n is 1 and R<2> represents a methyl group in the 7-position, and (iv) R<1> is other than dimethylcarbamoyl when (R<1>)n represents a methoxy or tert-butyl group in the 5-position or two methyl groups in the 6-and 7-positions, are new compounds which possess properties indicative of utility in the treatment of arthritic and related autoimmune disorders.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB838334001A GB8334001D0 (en) | 1983-12-21 | 1983-12-21 | Compositions of matter |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| ES542457A0 ES542457A0 (en) | 1985-12-16 |
| ES8603426A1 true ES8603426A1 (en) | 1985-12-16 |
Family
ID=10553616
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES538957A Expired ES8605516A1 (en) | 1983-12-21 | 1984-12-21 | Pyrazolopyridine derivatives |
| ES542457A Expired ES8603426A1 (en) | 1983-12-21 | 1985-04-22 | Pyrazolopyridine derivatives |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES538957A Expired ES8605516A1 (en) | 1983-12-21 | 1984-12-21 | Pyrazolopyridine derivatives |
Country Status (18)
| Country | Link |
|---|---|
| JP (1) | JPS60172979A (en) |
| KR (1) | KR850004758A (en) |
| AT (1) | ATA404684A (en) |
| AU (1) | AU3690684A (en) |
| BE (1) | BE901336A (en) |
| DE (1) | DE3447730A1 (en) |
| DK (1) | DK616784A (en) |
| ES (2) | ES8605516A1 (en) |
| FI (1) | FI845022L (en) |
| FR (1) | FR2556723A1 (en) |
| GB (2) | GB8334001D0 (en) |
| GR (1) | GR82507B (en) |
| IL (1) | IL73860A0 (en) |
| IT (1) | IT1178768B (en) |
| LU (1) | LU85690A1 (en) |
| NL (1) | NL8403874A (en) |
| SE (1) | SE8406478L (en) |
| ZA (1) | ZA849903B (en) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20070155738A1 (en) | 2005-05-20 | 2007-07-05 | Alantos Pharmaceuticals, Inc. | Heterobicyclic metalloprotease inhibitors |
| JP2010533173A (en) * | 2007-07-11 | 2010-10-21 | オークランド・ユニサーヴィシズ・リミテッド | Pyrazolo [1,5-a] pyridine and its use in cancer treatment |
| JP6816287B2 (en) * | 2016-09-07 | 2021-01-20 | シャンハイ ハイヘ ファーマシューティカル カンパニー リミテッドＳｈａｎｇｈａｉ Ｈａｉｈｅ Ｐｈａｒｍａｃｅｕｔｉｃａｌ Ｃｏ．， Ｌｔｄ | Pyridine and 5-membered aromatic ring compounds, their production methods and uses |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5154583A (en) * | 1974-11-01 | 1976-05-13 | Kyorin Seiyaku Kk | Shinkipirazoro * 1 55a * pirijinjudotaino seizoho |
| JPS5610114A (en) * | 1979-07-05 | 1981-02-02 | Grelan Pharmaceut Co Ltd | Novel analgesic and anti-inflammatory agent |
| GB2121799B (en) * | 1982-06-16 | 1985-07-10 | May & Baker Ltd | New pyrazolopyridine derivative |
-
1983
- 1983-12-21 GB GB838334001A patent/GB8334001D0/en active Pending
-
1984
- 1984-12-18 LU LU85690A patent/LU85690A1/en unknown
- 1984-12-19 SE SE8406478A patent/SE8406478L/en not_active Application Discontinuation
- 1984-12-19 JP JP59268203A patent/JPS60172979A/en active Pending
- 1984-12-19 GR GR82507A patent/GR82507B/en unknown
- 1984-12-19 ZA ZA849903A patent/ZA849903B/en unknown
- 1984-12-19 KR KR1019840008098A patent/KR850004758A/en not_active Application Discontinuation
- 1984-12-19 FI FI845022A patent/FI845022L/en not_active Application Discontinuation
- 1984-12-19 GB GB08431986A patent/GB2153818B/en not_active Expired
- 1984-12-19 AU AU36906/84A patent/AU3690684A/en not_active Abandoned
- 1984-12-19 IL IL73860A patent/IL73860A0/en unknown
- 1984-12-20 DK DK616784A patent/DK616784A/en not_active Application Discontinuation
- 1984-12-20 BE BE0/214208A patent/BE901336A/en not_active IP Right Cessation
- 1984-12-20 AT AT0404684A patent/ATA404684A/en not_active IP Right Cessation
- 1984-12-20 FR FR8419522A patent/FR2556723A1/en not_active Withdrawn
- 1984-12-20 NL NL8403874A patent/NL8403874A/en not_active Application Discontinuation
- 1984-12-21 IT IT24176/84A patent/IT1178768B/en active
- 1984-12-21 ES ES538957A patent/ES8605516A1/en not_active Expired
- 1984-12-21 DE DE19843447730 patent/DE3447730A1/en not_active Withdrawn
-
1985
- 1985-04-22 ES ES542457A patent/ES8603426A1/en not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| SE8406478L (en) | 1985-06-22 |
| ES8605516A1 (en) | 1986-03-16 |
| IT8424176A0 (en) | 1984-12-21 |
| BE901336A (en) | 1985-06-20 |
| IL73860A0 (en) | 1985-03-31 |
| FI845022A0 (en) | 1984-12-19 |
| NL8403874A (en) | 1985-07-16 |
| ZA849903B (en) | 1985-08-28 |
| FR2556723A1 (en) | 1985-06-21 |
| LU85690A1 (en) | 1986-07-17 |
| AU3690684A (en) | 1985-07-04 |
| GB8334001D0 (en) | 1984-02-01 |
| DE3447730A1 (en) | 1985-07-04 |
| ES542457A0 (en) | 1985-12-16 |
| GB2153818A (en) | 1985-08-29 |
| DK616784A (en) | 1985-06-22 |
| GB8431986D0 (en) | 1985-01-30 |
| KR850004758A (en) | 1985-07-27 |
| GR82507B (en) | 1985-04-22 |
| GB2153818B (en) | 1987-07-29 |
| FI845022L (en) | 1985-06-22 |
| JPS60172979A (en) | 1985-09-06 |
| SE8406478D0 (en) | 1984-12-19 |
| ATA404684A (en) | 1987-08-15 |
| DK616784D0 (en) | 1984-12-20 |
| IT1178768B (en) | 1987-09-16 |
| ES538957A0 (en) | 1986-03-16 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| AU577079B2 (en) | Benzo/thieno-imidazodiazepine derivatives | |
| IE820421L (en) | Imidazodiazepines | |
| GEP19970661B (en) | Process for preparing arylcyclobutyl alkylamine derivatives | |
| ES8802518A1 (en) | Heterocyclic substituted-phenoxyalkyl-isoxazoles and-furans, their preparation and use as antiviral agents. | |
| ATE217615T1 (en) | SUBSTITUTED 5-RING HETEROCYCLES, THEIR PRODUCTION AND THEIR USE | |
| ATE25682T1 (en) | INDOL-3-CARBOXAMIDE DERIVATIVES. | |
| ES8504130A1 (en) | 2-Quinolone derivatives. | |
| EP0259835A3 (en) | Pyridazinone derivatives | |
| TW324009B (en) | Pyrazole condensation ring derivative, its production process and its use as androgen inhibitor | |
| ES8605516A1 (en) | Pyrazolopyridine derivatives | |
| IE780512L (en) | Thieno-pyridines | |
| ATE102626T1 (en) | HETEROCYCLIC COMPOUNDS, THEIR REPRESENTATION AND USE. | |
| AU599227B2 (en) | Bicyclic sulfonamide derivatives and process therefor | |
| ATE49212T1 (en) | TRICYCLIC DERIVATIVES OF THIDIAZOLOXIDES. | |
| MX9709465A (en) | 2-substituted benzimidazole derivatives as inhibitors of smooth muscle cell proliferation. | |
| MY103572A (en) | 3,4-dihydro-2-alkyl-3-oxo-n-aryl-2h-[1] benzothieno [3,2-e]-1,2-thiazine-4-carboxamide-1, 1-dioxides. | |
| GR79443B (en) | ||
| ES2010089A6 (en) | Antipsychotic gamma-carboline n-oxides. | |
| ES8800255A1 (en) | N6-benzopyrano- and benzothiopyrano-adenosines. | |
| KR840008025A (en) | 5-imino-1,2-dithiol-one compound and its preparation | |
| ES8304956A1 (en) | New benzothiazine derivatives, processes for preparation thereof and use thereof. | |
| KR950700225A (en) | Benzodiazepine derivatives useful as CCK-receptor antagonists (BENZODIAZEPIN DERIVATIVES USEFUL AS CCK-RECEPTOR ANTAGONISTS) | |
| ES8402824A1 (en) | Imidazolecarboxylic acid derivatives. | |
| ATE28192T1 (en) | 4-ALKYLIMIDAZOLE DERIVATIVES, THEIR PREPARATION AND USE. | |
| ES8505654A1 (en) | Antiarthritic pyridylaminoethene disulfonyl compounds and use |