ES8602004A1 - Procedimiento para la obtencion de la s(+)-6-fluorospiro(cro-man-4,4'-imidazolidina)-2',5'-diona - Google Patents

Procedimiento para la obtencion de la s(+)-6-fluorospiro(cro-man-4,4'-imidazolidina)-2',5'-diona

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Publication number
ES8602004A1
ES8602004A1 ES539131A ES539131A ES8602004A1 ES 8602004 A1 ES8602004 A1 ES 8602004A1 ES 539131 A ES539131 A ES 539131A ES 539131 A ES539131 A ES 539131A ES 8602004 A1 ES8602004 A1 ES 8602004A1
Authority
ES
Spain
Prior art keywords
prepn
diabetes mellitus
treating agent
organic solvent
dione
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES539131A
Other languages
English (en)
Other versions
ES539131A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Inke SA
Original Assignee
Inke SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Inke SA filed Critical Inke SA
Priority to ES539131A priority Critical patent/ES539131A0/es
Publication of ES8602004A1 publication Critical patent/ES8602004A1/es
Publication of ES539131A0 publication Critical patent/ES539131A0/es
Granted legal-status Critical Current

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  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

PROCEDIMIENTO PARA LA OBTENCION DE LA S( )-6-FLUOROSPIRO (CROMAN-4,4-IMIDAZOLIDINA)-2-5-DIONA. CONSISTE EN HACER REACCIONAR LA MEZCLA RACEMICA DE 6-FLUOROSPIRO (CROMAN-4,4-IMIDAZOLINA)-2,5-DIONA CON UNA (-) AMINA SINTETICA OPTICAMENTE ACTIVA EN UN DISOLVENTE ORGANICO ADECUADO Y SEPARAR POR CRISTALIZACION FRACCIONADA LAS SALES DIASTEREOISOMERICAS, AISLANDO EL PRODUCTO DESEADO POR HIDROLISIS ACIDA DE LA SAL MENOS SOLUBLE FINALMENTE. LOS REACTIVOS SE UTILIZAN SEGUN LA RELACION MOLAR 1:1 DE LA REACCION ESTEQUIOMETRICA, UTILIZANDO UN DISOLVENTE ORGANICO. APLICADO EN EL TRATAMIENTO DE LA DIABETES MELLITUS Y ESTADOS ASOCIADOS.
ES539131A 1984-12-28 1984-12-28 Procedimiento para la obtencion de la s(+)-6-fluorospiro(cro-man-4,4'-imidazolidina)-2',5'-diona Granted ES539131A0 (es)

Priority Applications (1)

Application Number Priority Date Filing Date Title
ES539131A ES539131A0 (es) 1984-12-28 1984-12-28 Procedimiento para la obtencion de la s(+)-6-fluorospiro(cro-man-4,4'-imidazolidina)-2',5'-diona

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ES539131A ES539131A0 (es) 1984-12-28 1984-12-28 Procedimiento para la obtencion de la s(+)-6-fluorospiro(cro-man-4,4'-imidazolidina)-2',5'-diona

Publications (2)

Publication Number Publication Date
ES8602004A1 true ES8602004A1 (es) 1985-11-16
ES539131A0 ES539131A0 (es) 1985-11-16

Family

ID=8488427

Family Applications (1)

Application Number Title Priority Date Filing Date
ES539131A Granted ES539131A0 (es) 1984-12-28 1984-12-28 Procedimiento para la obtencion de la s(+)-6-fluorospiro(cro-man-4,4'-imidazolidina)-2',5'-diona

Country Status (1)

Country Link
ES (1) ES539131A0 (es)

Also Published As

Publication number Publication date
ES539131A0 (es) 1985-11-16

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Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 19970612