ES8601307A1 - Procedimiento de obtencion de polipeptidos - Google Patents
Procedimiento de obtencion de polipeptidosInfo
- Publication number
- ES8601307A1 ES8601307A1 ES540009A ES540009A ES8601307A1 ES 8601307 A1 ES8601307 A1 ES 8601307A1 ES 540009 A ES540009 A ES 540009A ES 540009 A ES540009 A ES 540009A ES 8601307 A1 ES8601307 A1 ES 8601307A1
- Authority
- ES
- Spain
- Prior art keywords
- human cytomegalovirus
- antigenic determinant
- antibodies
- hybridomas secreting
- monoclonal antibodies
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 241000701024 Human betaherpesvirus 5 Species 0.000 title abstract 4
- 229920001184 polypeptide Polymers 0.000 title abstract 4
- 102000004196 processed proteins & peptides Human genes 0.000 title abstract 4
- 108090000765 processed proteins & peptides Proteins 0.000 title abstract 4
- 230000000890 antigenic effect Effects 0.000 title 1
- 210000004408 hybridoma Anatomy 0.000 title 1
- 230000003248 secreting effect Effects 0.000 title 1
- CSCPPACGZOOCGX-UHFFFAOYSA-N Acetone Chemical compound CC(C)=O CSCPPACGZOOCGX-UHFFFAOYSA-N 0.000 abstract 2
- 210000005260 human cell Anatomy 0.000 abstract 2
- 238000006243 chemical reaction Methods 0.000 abstract 1
- 210000000805 cytoplasm Anatomy 0.000 abstract 1
- 229940042399 direct acting antivirals protease inhibitors Drugs 0.000 abstract 1
- 238000010166 immunofluorescence Methods 0.000 abstract 1
- 239000000137 peptide hydrolase inhibitor Substances 0.000 abstract 1
- 102000004169 proteins and genes Human genes 0.000 abstract 1
- 108090000623 proteins and genes Proteins 0.000 abstract 1
- 230000003612 virological effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/08—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses
- C07K16/081—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses from DNA viruses
- C07K16/085—Herpetoviridae, e.g. pseudorabies virus, Epstein-Barr virus
- C07K16/089—Cytomegalovirus
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Virology (AREA)
- Genetics & Genomics (AREA)
- Medicinal Chemistry (AREA)
- Immunology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Tropical Medicine & Parasitology (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Abstract
PROCEDIMIENTO DE OBTENCION DE POLIPEPTIDOS. CONSISTE EN HACER REACCIONAR PARA FORMAR UN COMPLEJO ANTIGENO-ANTICUERPO LOS POLIPEPTIDOS CITOPLASMICOS OBTENIDOS PREVIAMENTE A PARTIR DE UN EXTRACTO CITOPLASMICO DE CELULAS INFECTADAS CON UNOS ANTICUERPOS MONOCLONALES ANTICITOMEGALOVIRUS HUMANOS QUE SE FIJAN SOBRE UN SOPORTE LIQUIDO. LOS ANTICUERPOS MONOCLONALES UTILIZADOS POSEEN LA CAPACIDAD DE NEUTRALIZAR INDIFERENTEMENTE UNAS CEPAS DE HCMV AD-169 UNAS CEPAS HCMB TOWNE Y UNAS CEPAS HCMV DAVIS.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR8305384A FR2543570B1 (fr) | 1983-03-31 | 1983-03-31 | Anticorps monoclonaux anticytomegalovirus humains, hybridomes secreteurs de ces anticorps et polypeptides porteurs d'un determinant antigenique sequentiel de cytomegalovirus humains |
Publications (2)
Publication Number | Publication Date |
---|---|
ES540009A0 ES540009A0 (es) | 1985-11-16 |
ES8601307A1 true ES8601307A1 (es) | 1985-11-16 |
Family
ID=9287460
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES531436A Expired ES8505406A1 (es) | 1983-03-31 | 1984-03-30 | Procedimiento de obtener y aislar hibridomas secretores de anticuerpos, procedimiento de obtener anticuerpos y metodo de obtener polipeptidos |
ES540009A Expired ES8601307A1 (es) | 1983-03-31 | 1985-01-31 | Procedimiento de obtencion de polipeptidos |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES531436A Expired ES8505406A1 (es) | 1983-03-31 | 1984-03-30 | Procedimiento de obtener y aislar hibridomas secretores de anticuerpos, procedimiento de obtener anticuerpos y metodo de obtener polipeptidos |
Country Status (4)
Country | Link |
---|---|
EP (1) | EP0122841A1 (es) |
JP (1) | JPS59231026A (es) |
ES (2) | ES8505406A1 (es) |
FR (1) | FR2543570B1 (es) |
Families Citing this family (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB8404368D0 (en) * | 1984-02-20 | 1984-03-28 | Cogent Ltd | Monoclonal antibodies to human cytomegalovirus |
US4783399A (en) * | 1984-05-04 | 1988-11-08 | Scripps Clinic And Research Foundation | Diagnostic system for the detection of cytomegalovirus |
FR2590674B1 (fr) * | 1985-11-25 | 1989-03-03 | Inst Nat Sante Rech Med | Nouveaux reactifs de diagnostic |
AU592142B2 (en) * | 1985-11-25 | 1990-01-04 | Cytogen Corporation | Modified viral glycoproteins, diagnostic and therapeutic uses therefore |
WO1987003602A1 (en) * | 1985-12-06 | 1987-06-18 | Teijin Limited | Anticytomegaloviral human monoclonal antibody and process for its preparation |
DE3619902A1 (de) * | 1986-06-13 | 1988-03-03 | Biotechnolog Forschung Gmbh | Cmv-dna-strukturen, expressionsvektor dafuer, cmv-proteinstrukturen und deren verwendung |
US5124440A (en) * | 1986-11-24 | 1992-06-23 | The Childrens Hospital, Inc. | Antibody and T cell recognition sites on glycoproteins comprising the GCI complex of human cytomegalovirus |
US5153311A (en) * | 1986-11-24 | 1992-10-06 | The Children's Hospital, Incorporated | Immunogenic glycoproteins of human cytomegalovirus gCII |
US5248768A (en) * | 1986-11-24 | 1993-09-28 | The Children's Hospital, Incorporated | Immunogenic glycoproteins of human cytomegalovirus |
JPH02504551A (ja) * | 1987-08-07 | 1990-12-20 | ザ・チルドレンズ・ホスピタル,インコーポレイテッド | サイトメガロウイルスの糖タンパク質aと反応性のモノクローナル抗体 |
US7947274B2 (en) | 2007-01-04 | 2011-05-24 | Humabs, LLC. | Human cytomegalovirus neutralising antibodies and use thereof |
GB0700133D0 (en) | 2007-01-04 | 2007-02-14 | Humabs Llc | Human cytomegalovirus neutralising antibodies and use thereof |
SG10201706350PA (en) | 2008-07-16 | 2017-09-28 | Inst For Res In Biomedicine | Human cytomegalovirus neutralizing antibodies and use thereof |
JP5833565B2 (ja) | 2009-12-23 | 2015-12-16 | 4−アンティボディ・アクチェンゲゼルシャフト4−Antibody Ag | ヒトサイトメガロウイルスに対する結合メンバー |
-
1983
- 1983-03-31 FR FR8305384A patent/FR2543570B1/fr not_active Expired
-
1984
- 1984-03-30 JP JP59063091A patent/JPS59231026A/ja active Pending
- 1984-03-30 EP EP84400648A patent/EP0122841A1/fr not_active Withdrawn
- 1984-03-30 ES ES531436A patent/ES8505406A1/es not_active Expired
-
1985
- 1985-01-31 ES ES540009A patent/ES8601307A1/es not_active Expired
Also Published As
Publication number | Publication date |
---|---|
FR2543570A1 (fr) | 1984-10-05 |
EP0122841A1 (fr) | 1984-10-24 |
ES540009A0 (es) | 1985-11-16 |
FR2543570B1 (fr) | 1985-08-09 |
ES531436A0 (es) | 1985-06-01 |
JPS59231026A (ja) | 1984-12-25 |
ES8505406A1 (es) | 1985-06-01 |
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