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SERRANO PUNYED M ANTONIA
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SERRANO PUNYED M ANTONIA
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Priority to ES538704ApriorityCriticalpatent/ES8601227A1/en
Publication of ES538704A0publicationCriticalpatent/ES538704A0/en
Publication of ES8601227A1publicationCriticalpatent/ES8601227A1/en
Pharmaceuticals Containing Other Organic And Inorganic Compounds
(AREA)
Abstract
The process comprises reaction of O-phenylene diamine of formula (II) with chloroacetic acid to give 2-oxo-1234-tetrahydroquinoxaline of formula (III). This latter is reacted with an oxidising agent to give 2-hydroxyquinolaxine of formula (IV) which is then reacted with OO-diethylchlorothiophosphate 1-P(S)(OCH2CH3)2 in the presence of a base such as sodium hydroxide under solid liq. phase transfer conditions yielding acid of formula (I).
ES538704A1984-12-181984-12-18Preparation of a derivative of thiophosphoric acid
ExpiredES8601227A1
(en)