ES8507455A1 - Un procedimiento para la preparacion de s-3-(4-(2-ciclohexenon)) propionato de alquilo c1-3 - Google Patents

Un procedimiento para la preparacion de s-3-(4-(2-ciclohexenon)) propionato de alquilo c1-3

Info

Publication number
ES8507455A1
ES8507455A1 ES529927A ES529927A ES8507455A1 ES 8507455 A1 ES8507455 A1 ES 8507455A1 ES 529927 A ES529927 A ES 529927A ES 529927 A ES529927 A ES 529927A ES 8507455 A1 ES8507455 A1 ES 8507455A1
Authority
ES
Spain
Prior art keywords
chiral
hydroxypropyl
phenyl
cyclohexanol
substituted
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES529927A
Other languages
English (en)
Other versions
ES529927A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pfizer Inc
Original Assignee
Pfizer Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Inc filed Critical Pfizer Inc
Publication of ES8507455A1 publication Critical patent/ES8507455A1/es
Publication of ES529927A0 publication Critical patent/ES529927A0/es
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C62/00—Compounds having carboxyl groups bound to carbon atoms of rings other than six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C62/30—Unsaturated compounds
    • C07C62/34—Unsaturated compounds containing ether groups, groups, groups, or groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C41/00—Preparation of ethers; Preparation of compounds having groups, groups or groups
    • C07C41/01—Preparation of ethers
    • C07C41/18—Preparation of ethers by reactions not forming ether-oxygen bonds
    • C07C41/26—Preparation of ethers by reactions not forming ether-oxygen bonds by introduction of hydroxy or O-metal groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C43/00—Ethers; Compounds having groups, groups or groups
    • C07C43/02—Ethers
    • C07C43/20—Ethers having an ether-oxygen atom bound to a carbon atom of a six-membered aromatic ring
    • C07C43/23—Ethers having an ether-oxygen atom bound to a carbon atom of a six-membered aromatic ring containing hydroxy or O-metal groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
    • C07C51/42—Separation; Purification; Stabilisation; Use of additives
    • C07C51/487—Separation; Purification; Stabilisation; Use of additives by treatment giving rise to chemical modification

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

PROCEDIMIENTO PARA LA PREPARACION DE S-3-4-(CICLOHEXENON)PROPIONATO DE ALQUILO C1-3.COMPRENDE LAS SIGUIENTES ETAPAS: PRIMERA, RESOLUCION DEL ACIDO (G)-ENDO- O (G)-EXO-1-METOXIBICICLO 2.2.2OCT-5-EN-2-CARBOXILICO POR CRISTALIZACION DE LA SAL DE(B) EFEDRINA DEL ACIDO (-)-ENDO- O DE LA SAL DE (-)-EFEDRINA DEL ACIDO (-)-EXO-1-METOXIBICICLO 2.2.2-OCT-5-EN-2-CARBOXILICO EN UN DISOLVENTE; SEGUNDA, TRATAMIENTO CON UNA SOLUCION ACUOSA ACIDA DE DICHA SAL DE (B) O (-)-EFEDRINA, PARA PRODUCIR ACIDO (-)-ENDO O (-)-EXO-1-METOXIBICICLO 2.2.2 OCT-5-EN-2-CARBOXILICO; TERCERA, ESTERIFICACION DE DICHO ACIDO; CUARTA, DESMETILACION DE DICHO (-)-ENDO- O (-)-EXO-METOXICARBOXILATO, MEDIANTE LA ACCION DEL TRIBOMURO DE BROMO; Y POR ULTIMO, TRANSPOSICION CATALIZADA POR BASES DE DICHO (B)-ENDO-.
ES529927A 1983-02-22 1984-02-21 Un procedimiento para la preparacion de s-3-(4-(2-ciclohexenon)) propionato de alquilo c1-3 Granted ES529927A0 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/468,616 US4585888A (en) 1983-02-22 1983-02-22 Synthetic method for a chiral 3-(substituted-phenyl)-4-(3-hydroxypropyl)cyclohexanol

Publications (2)

Publication Number Publication Date
ES8507455A1 true ES8507455A1 (es) 1985-09-01
ES529927A0 ES529927A0 (es) 1985-09-01

Family

ID=23860532

Family Applications (1)

Application Number Title Priority Date Filing Date
ES529927A Granted ES529927A0 (es) 1983-02-22 1984-02-21 Un procedimiento para la preparacion de s-3-(4-(2-ciclohexenon)) propionato de alquilo c1-3

Country Status (15)

Country Link
US (1) US4585888A (es)
EP (1) EP0118244B1 (es)
JP (1) JPS59157042A (es)
KR (1) KR860001545B1 (es)
AU (1) AU548190B2 (es)
DE (1) DE3461784D1 (es)
DK (1) DK82384A (es)
ES (1) ES529927A0 (es)
FI (1) FI840704A (es)
GR (1) GR79998B (es)
HU (1) HUT35624A (es)
IL (1) IL71016A0 (es)
PL (1) PL246292A1 (es)
PT (1) PT78125B (es)
YU (1) YU30684A (es)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4719310A (en) * 1985-12-23 1988-01-12 Merck & Co., Inc. Ester and amide substituted (2,3-dihydro-4-(3-oxo-1-cyclohexen-1-yl)phenoxy)alkanoic acids and their salts
US4625047A (en) * 1985-12-23 1986-11-25 Merck & Co., Inc. Substituted (2,3-dihydro-4-(3-oxo-1-cyclohexen-1-yl)phenoxy) alkanoic acids, their derivatives and their salts
AUPR701101A0 (en) * 2001-08-14 2001-09-06 Commonwealth Scientific And Industrial Research Organisation Agonists and antagonists of 5ht3-like receptors of invertebrates as pesticides

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4189431A (en) * 1975-08-04 1980-02-19 The Board of Trustees of Leland Stanford Junior University Alkinyl terminating groups in biogenetic-like cyclizations to steroids
US4371720A (en) * 1980-09-19 1983-02-01 Pfizer Inc. 2-Hydroxy-4-(substituted) phenyl cycloalkanes and derivatives

Also Published As

Publication number Publication date
EP0118244A2 (en) 1984-09-12
KR840007552A (ko) 1984-12-08
DK82384D0 (da) 1984-02-21
EP0118244B1 (en) 1986-12-30
EP0118244A3 (en) 1984-10-17
US4585888A (en) 1986-04-29
KR860001545B1 (ko) 1986-10-04
JPS59157042A (ja) 1984-09-06
HUT35624A (en) 1985-07-29
AU548190B2 (en) 1985-11-28
FI840704A0 (fi) 1984-02-21
PT78125B (en) 1986-07-17
PL246292A1 (en) 1985-07-30
PT78125A (en) 1984-03-01
DE3461784D1 (en) 1987-02-05
GR79998B (es) 1984-10-31
FI840704A (fi) 1984-08-23
IL71016A0 (en) 1984-05-31
ES529927A0 (es) 1985-09-01
DK82384A (da) 1984-08-23
YU30684A (en) 1986-08-31
AU2474884A (en) 1984-08-30

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